Immunogenicity 14804
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
EXOC6
Transcript ID
uc010qnr.2
HLA INFO
B*27:02
TCR INFO
No TCR info found!
Full length protein sequence (820 aa)
MCCVG
1
GAGSC
6
SDTGK
11
LGACR
16
AMLEE
21
ETDQT
26
YENVL
31
AEIQS
36
FELPV
41
EATLR
46
SVYDD
51
QPNAH
56
KKFME
61
KLDAC
66
IRNHD
71
KEIEK
76
MCNFH
81
HQGFV
86
DAITE
91
LLKVR
96
TDAEK
101
LKVQV
106
TDTNR
111
RFQDA
116
GKEVI
121
VHTED
126
IIRCR
131
IQQRN
136
ITTVV
141
EKLQL
146
CLPVL
151
EMYSK
156
LKEQM
161
SAKRY
166
YSALK
171
TMEQL
176
ENVYF
181
PWVSQ
186
YRFCQ
191
LMIEN
196
LPKLR
201
EDIKE
206
ISMSD
211
LKDFL
216
ESIRK
221
HSDKI
226
GETAM
231
KQAQH
236
QKTFS
241
VSLQK
246
QNKMK
251
FGKNM
256
YINRD
261
RIPEE
266
RNETV
271
LKHSL
276
EEEDE
281
NEEEI
286
LTVQD
291
LVDFS
296
PVYRC
301
LHIYS
306
VLGDE
311
ETFEN
316
YYRKQ
321
RKKQA
326
RLVLQ
331
PQSNM
336
HETVD
341
GYRRY
346
FTQIV
351
GFFVV
356
EDHIL
361
HVTQG
366
LVTRA
371
YTDEL
376
WNMAL
381
SKIIA
386
VLRAH
391
SSYCT
396
DPDLV
401
LELKN
406
LTVIF
411
ADTLQ
416
GYGFP
421
VNRLF
426
DLLFE
431
IRDQY
436
NETLL
441
KKWAG
446
VFRDI
451
FEEDN
456
YSPIP
461
VVNEE
466
EYKIV
471
ISKFP
476
FQDPD
481
LEKQS
486
FPKKF
491
PMSQS
496
VPHIY
501
IQVKE
506
FIYAS
511
LKFSE
516
SLHRS
521
STEID
526
DMLRK
531
STNLL
536
LTRTL
541
SSCLL
546
NLIRK
551
PHIGL
556
TELVQ
561
IIINT
566
THLEQ
571
ACKYL
576
EDFIT
581
NITNI
586
SQETV
591
HTTRL
596
YGLST
601
FKDAR
606
HAAEG
611
EIYTK
616
LNQKI
621
DEFVQ
626
LADYD
631
WTMSE
636
PDGRA
641
SGYLM
646
DLINF
651
LRSIF
656
QVFTH
661
LPGKV
666
AQTAC
671
MSACQ
676
HLSTS
681
LMQML
686
LDSEL
691
KQISM
696
GAVQQ
701
FNLDV
706
IQCEL
711
FASSE
716
PVPGF
721
QGDTL
726
QLAFI
731
DLRQL
736
LDLFM
741
VWDWS
746
TYLAD
751
YGQPA
756
SKYLR
761
VNPNT
766
ALTLL
771
EKMKD
776
TSKKN
781
NIFAQ
786
FRKND
791
RDKQK
796
LIETV
801
VKQLR
806
SLVNG
811
MSQHM
816
Mutation Information
DNA mutation:
None
Peptide Range:
288 ~ 312
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"EEILTVQDLVDFSPVYRCLHIYSVL
||||||||||||.||||||||||||
Mutant:
EEILTVQDLVDFFPVYRCLHIYSVL"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) EXOC6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay