Immunogenicity 14886
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
RYR3
Transcript ID
uc010bar.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (4865 aa)
MAEGG
1
EGGED
6
EIQFL
11
RTEDE
16
VVLQC
21
IATIH
26
KEQRK
31
FCLAA
36
EGLGN
41
RLCFL
46
EPTSE
51
AKYIP
56
PDLCV
61
CNFVL
66
EQSLS
71
VRALQ
76
EMLAN
81
TGENG
86
GEGAA
91
QGGGH
96
RTLLY
101
GHAVL
106
LRHSF
111
SGMYL
116
TCLTT
121
SRSQT
126
DKLAF
131
DVGLR
136
EHATG
141
EACWW
146
TIHPA
151
SKQRS
156
EGEKV
161
RIGDD
166
LILVS
171
VSSER
176
YLHLS
181
VSNGN
186
IQVDA
191
SFMQT
196
LWNVH
201
PTCSG
206
SSIEE
211
GYLLG
216
GHVVR
221
LFHGH
226
DECLT
231
IPSTD
236
QNDSQ
241
HRRIF
246
YEAGG
251
AGTRA
256
RSLWR
261
VEPLR
266
ISWSG
271
SNIRW
276
GQAFR
281
LRHLT
286
TGHYL
291
ALTED
296
QGLIL
301
QDRAK
306
SDTKS
311
TAFSF
316
RASKE
321
LKEKL
326
DSSHK
331
RDIEG
336
MGVPE
341
IKYGD
346
SVCFV
351
QHIAS
356
GLWVT
361
YKAQD
366
AKTSR
371
LGPLK
376
RKVIL
381
HQEGH
386
MDDGL
391
TLQRC
396
QREES
401
QAARI
406
IRNTT
411
ALFSQ
416
FVSGN
421
NRTAA
426
PITLP
431
IEEVL
436
QTLQD
441
LIAYF
446
QPPEE
451
EMRHE
456
DKQNK
461
LRSLK
466
NRQNL
471
FKEEG
476
MLALV
481
LNCID
486
RLNVY
491
NSVAH
496
FAGIA
501
REESG
506
MAWKE
511
ILNLL
516
YKLLA
521
ALIRG
526
NRNNC
531
AQFSN
536
NLDWL
541
ISKLD
546
RLESS
551
SGILE
556
VLHCI
561
LTESP
566
EALNL
571
IAEGH
576
IKSII
581
SLLDK
586
HGRNH
591
KVLDI
596
LCSLC
601
LCNGV
606
AVRAN
611
QNLIC
616
DNLLP
621
RRNLL
626
LQTRL
631
INDVT
636
SIRPN
641
IFLGV
646
AEGSA
651
QYKKW
656
YFELI
661
IDQVD
666
PFLTA
671
EPTHL
676
RVGWA
681
SSSGY
686
APYPG
691
GGEGW
696
GGNGV
701
GDDLY
706
SYGFD
711
GLHLW
716
SGRIP
721
RAVAS
726
INQHL
731
LRSDD
736
VVSCC
741
LDLGV
746
PSISF
751
RINGQ
756
PVQGM
761
FENFN
766
TDGLF
771
FPVMS
776
FSAGV
781
KVRFL
786
MGGRH
791
GEFKF
796
LPPSG
801
YAPCY
806
EALLP
811
KEKMR
816
LEPVK
821
EYKRD
826
ADGIR
831
DLLGT
836
TQFLS
841
QASFI
846
PCPVD
851
TSQVI
856
LPPHL
861
EKIRD
866
RLAEN
871
IHELW
876
GMNKI
881
ELGWT
886
FGKIR
891
DDNKR
896
QHPCL
901
VEFSK
906
LPETE
911
KNYNL
916
QMSTE
921
TLKTL
926
LALGC
931
HIAHV
936
NPAAE
941
EDLKK
946
VKLPK
951
NYMMS
956
NGYKP
961
APLDL
966
SDVKL
971
LPPQE
976
ILVDK
981
LAENA
986
HNVWA
991
KDRIK
996
QGWTY
1001
GIQQD
1006
LKNKR
1011
NPRLV
1016
PYALL
1021
DERTK
1026
KSNRD
1031
SLREA
1036
VRTFV
1041
GYGYN
1046
IEPSD
1051
QELAD
1056
SAVEK
1061
VSIDK
1066
IRFFR
1071
VERSY
1076
AVRSG
1081
KWYFE
1086
FEVVT
1091
GGDMR
1096
VGWAR
1101
PGCRP
1106
DVELG
1111
ADDQA
1116
FVFEG
1121
NRGQR
1126
WHQGS
1131
GYFGR
1136
TWQPG
1141
DVVGC
1146
MINLD
1151
DASMI
1156
FTLNG
1161
ELLIT
1166
NKGSE
1171
LAFAD
1176
YEIEN
1181
GFVPI
1186
CCLGL
1191
SQIGR
1196
MNLGT
1201
DASTF
1206
KFYTM
1211
CGLQE
1216
GFEPF
1221
AVNMN
1226
RDVAM
1231
WFSKR
1236
LPTFV
1241
NVPKD
1246
HPHIE
1251
VMRID
1256
GTMDS
1261
PPCLK
1266
VTHKT
1271
FGTQN
1276
SNADM
1281
IYCRL
1286
SMPVE
1291
CHSSF
1296
SHSPC
1301
LDSEA
1306
FQKRK
1311
QMQEI
1316
LSHTT
1321
TQCYY
1326
AIRIF
1331
AGQDP
1336
SCVWV
1341
GWVTP
1346
DYHLY
1351
SEKFD
1356
LNKNC
1361
TVTVT
1366
LGDER
1371
GRVHE
1376
SVKRS
1381
NCYMV
1386
WGGDI
1391
VASSQ
1396
RSNRS
1401
NVDLE
1406
IGCLV
1411
DLAMG
1416
MLSFS
1421
ANGKE
1426
LGTCY
1431
QVEPN
1436
TKVFP
1441
AVFLQ
1446
PTSTS
1451
LFQFE
1456
LGKLK
1461
NAMPL
1466
SAAIF
1471
RSEEK
1476
NPVPQ
1481
CPPRL
1486
DVQTI
1491
QPVLW
1496
SRMPN
1501
SFLKV
1506
ETERV
1511
SERHG
1516
WVVQC
1521
LEPLQ
1526
MMALH
1531
IPEEN
1536
RCVDI
1541
LELCE
1546
QEDLM
1551
RFHYH
1556
TLRLY
1561
SAVCA
1566
LGNSR
1571
VAYAL
1576
CSHVD
1581
LSQLF
1586
YAIDN
1591
KYLPG
1596
LLRSG
1601
FYDLL
1606
ISIHL
1611
ASAKE
1616
RKLMM
1621
KNEYI
1626
IPITS
1631
TTRNI
1636
RLFPD
1641
ESKRH
1646
GLPGV
1651
GLRTC
1656
LKPGF
1661
RFSTP
1666
CFVVT
1671
GEDHQ
1676
KQSPE
1681
IPLES
1686
LRTKA
1691
LSMLT
1696
EAVQC
1701
SGAHI
1706
RDPVG
1711
GSVEF
1716
QFVPV
1721
LKLIG
1726
TLLVM
1731
GVFDD
1736
DDVRQ
1741
ILLLI
1746
DPSVF
1751
GEHSA
1756
GTEEG
1761
AEKEE
1766
VTQVE
1771
EKAVE
1776
AGEKA
1781
GKEAP
1786
VKGLL
1791
QTRLP
1796
ESVKL
1801
QMCEL
1806
LSYLC
1811
DCELQ
1816
HRVEA
1821
IVAFG
1826
DIYVS
1831
KLQAN
1836
QKFRY
1841
NELMQ
1846
ALNMS
1851
AALTA
1856
RKTKE
1861
FRSPP
1866
QEQIN
1871
MLLNF
1876
QLGEN
1881
CPCPE
1886
EIREE
1891
LYDFH
1896
EDLLL
1901
HCGVP
1906
LEEEE
1911
EEEED
1916
TSWTG
1921
KLCAL
1926
VYKIK
1931
GPPKP
1936
EKEQP
1941
TEEEE
1946
RCPTT
1951
LKELI
1956
SQTMI
1961
CWAQE
1966
DQIQD
1971
SELVR
1976
MMFNL
1981
LRRQY
1986
DSIGE
1991
LLQAL
1996
RKTYT
2001
ISHTS
2006
VSDTI
2011
NLLAA
2016
LGQIR
2021
SLLSV
2026
RMGKE
2031
EELLM
2036
INGLG
2041
DIMNN
2046
KVFYQ
2051
HPNLM
2056
RVLGM
2061
HETVM
2066
EVMVN
2071
VLGTE
2076
KSQIA
2081
FPKMV
2086
ASCCR
2091
FLCYF
2096
CRISR
2101
QNQKA
2106
MFEHL
2111
SYLLE
2116
NSSVG
2121
LASPS
2126
MRGST
2131
PLDVA
2136
ASSVM
2141
DNNEL
2146
ALSLE
2151
EPDLE
2156
KVVTY
2161
LAGCG
2166
LQSCP
2171
MLLAK
2176
GYPDV
2181
GWNPI
2186
EGERY
2191
LSFLR
2196
FAVFV
2201
NSESV
2206
EENAS
2211
VVVKL
2216
LIRRP
2221
ECFGP
2226
ALRGE
2231
GGNGL
2236
LAAMQ
2241
GAIKI
2246
SENPA
2251
LDLPS
2256
QGYKR
2261
EVSTG
2266
DDEEE
2271
EEIVH
2276
MGNAI
2281
MSFYS
2286
ALIDL
2291
LGRCA
2296
PEMHL
2301
IQTGK
2306
GEAIR
2311
IRSIL
2316
RSLVP
2321
TEDLV
2326
GIISI
2331
PLKLP
2336
SLNKD
2341
GSVSE
2346
PDMAA
2351
NFCPD
2356
HKAPM
2361
VLFLD
2366
RVYGI
2371
KDQTF
2376
LLHLL
2381
EVGFL
2386
PDLRA
2391
SASLD
2396
TVSLS
2401
TTEAA
2406
LALNR
2411
YICSA
2416
VLPLL
2421
TRCAP
2426
LFAGT
2431
EHCTS
2436
LIDST
2441
LQTIY
2446
RLSKG
2451
RSLTK
2456
AQRDT
2461
IEECL
2466
LAICN
2471
HLRPS
2476
MLQQL
2481
LRRLV
2486
FDVPQ
2491
LNEYC
2496
KMPLK
2501
LLTNH
2506
YEQCW
2511
KYYCL
2516
PSGWG
2521
SYGLA
2526
VEEEL
2531
HLTEK
2536
LFWGI
2541
FDSLS
2546
HKKYD
2551
PDLFR
2556
MALPC
2561
LSAIA
2566
GALPP
2571
DYLDT
2576
RITAT
2581
LEKQI
2586
SVDAD
2591
GNFDP
2596
KPINT
2601
MNFSL
2606
PEKLE
2611
YIVTK
2616
YAEHS
2621
HDKWA
2626
CDKSQ
2631
SGWKY
2636
GISLD
2641
ENVKT
2646
HPLIR
2651
PFKTL
2656
TEKEK
2661
EIYRW
2666
PARES
2671
LKTML
2676
AVGWT
2681
VERTK
2686
EGEAL
2691
VQQRE
2696
NEKLR
2701
SVSQA
2706
NQGNS
2711
YSPAP
2716
LDLSN
2721
VVLSR
2726
ELQGM
2731
VEVVA
2736
ENYHN
2741
IWAKK
2746
KKLEL
2751
ESKGG
2756
GSHPL
2761
LVPYD
2766
TLTAK
2771
EKFKD
2776
REKAQ
2781
DLFKF
2786
LQVNG
2791
IIVSR
2796
GMKDM
2801
ELDAS
2806
SMEKR
2811
FAYKF
2816
LKKIL
2821
KYVDS
2826
AQEFI
2831
AHLEA
2836
IVSSG
2841
KTEKS
2846
PRDQE
2851
IKFFA
2856
KVLLP
2861
LVDQY
2866
FTSHC
2871
LYFLS
2876
SPLKP
2881
LSSSG
2886
YASHK
2891
EKEMV
2896
AGLFC
2901
KLAAL
2906
VRHRI
2911
SLFGS
2916
DSTTM
2921
VSCLH
2926
ILAQT
2931
LDTRT
2936
VMKSG
2941
SELVK
2946
AGLRA
2951
FFENA
2956
AEDLE
2961
KTSEN
2966
LKLGK
2971
FTHSR
2976
TQIKG
2981
VSQNI
2986
NYTTV
2991
ALLPI
2996
LTSIF
3001
EHVTQ
3006
HQFGM
3011
DLLLG
3016
DVQIS
3021
CYHIL
3026
CSLYS
3031
LGTGK
3036
NIYVE
3041
RQRPA
3046
LGECL
3051
ASLAA
3056
AIPVA
3061
FLEPT
3066
LNRYN
3071
PLSVF
3076
NTKTP
3081
RERSI
3086
LGMPD
3091
TVEDM
3096
CPDIP
3101
QLEGL
3106
MKEIN
3111
DLAES
3116
GARYT
3121
EMPHV
3126
IEVIL
3131
PMLCN
3136
YLSYW
3141
WERGP
3146
ENLPP
3151
STGPC
3156
CTKVT
3161
SEHLS
3166
LILGN
3171
ILKII
3176
NNNLG
3181
IDEAS
3186
WMKRI
3191
AVYAQ
3196
PIISK
3201
ARPDL
3206
LRSHF
3211
IPTLE
3216
KLKKK
3221
AVKTV
3226
QEEEQ
3231
LKADG
3236
KGDTQ
3241
EAELL
3246
ILDEF
3251
AVLCR
3256
DLYAF
3261
YPMLI
3266
RYVDN
3271
NRSNW
3276
LKSPD
3281
ADSDQ
3286
LFRMV
3291
AEVFI
3296
LWCKS
3301
HNFKR
3306
EEQNF
3311
VIQNE
3316
INNLA
3321
FLTGD
3326
SKSKM
3331
SKSGG
3336
QDQER
3341
KKTKR
3346
RGDLY
3351
SIQTS
3356
LIVAA
3361
LKKML
3366
PIGLN
3371
MCTPG
3376
DQELI
3381
SLAKS
3386
RYSHR
3391
DTDEE
3396
VREHL
3401
RNNLH
3406
LQEKS
3411
DDPAV
3416
KWQLN
3421
LYKDV
3426
LKSEE
3431
PFNPE
3436
KTVER
3441
VQRIS
3446
AAVFH
3451
LEQVE
3456
QPLRS
3461
KKAVW
3466
HKLLS
3471
KQRKR
3476
AVVAC
3481
FRMAP
3486
LYNLP
3491
RHRSI
3496
NLFLH
3501
GYQRF
3506
WIETE
3511
EYSFE
3516
EKLVQ
3521
DLAKS
3526
PKVEE
3531
EEEEE
3536
TEKQP
3541
DPLHQ
3546
IILYF
3551
SRNAL
3556
TERSK
3561
LEDDP
3566
LYTSY
3571
SSMMA
3576
KSCQS
3581
GEDEE
3586
EDEDK
3591
EKTFE
3596
EKEME
3601
KQKTL
3606
YQQAR
3611
LHERG
3616
AAEMV
3621
LQMIS
3626
ASKGE
3631
MSPMV
3636
VETLK
3641
LGIAI
3646
LNGGN
3651
AGVQQ
3656
KMLDY
3661
LKEKK
3666
DAGFF
3671
QSLSG
3676
LMQSC
3681
SVLDL
3686
NAFER
3691
QNKAE
3696
GLGMV
3701
TEEGT
3706
LIVRE
3711
RGEKV
3716
LQNDE
3721
FTRDL
3726
FRFLQ
3731
LLCEG
3736
HNSDF
3741
QNFLR
3746
TQMGN
3751
TTTVN
3756
VIIST
3761
VDYLL
3766
RLQES
3771
ISDFY
3776
WYYSG
3781
KDIID
3786
ESGQH
3791
NFSKA
3796
LAVTK
3801
QIFNS
3806
LTEYI
3811
QGPCI
3816
GNQQS
3821
LAHSR
3826
LWDAV
3831
VGFLH
3836
VFANM
3841
QMKLS
3846
QDSSQ
3851
IELLK
3856
ELLDL
3861
LQDMV
3866
VMLLS
3871
LLEGN
3876
VVNGT
3881
IGKQM
3886
VDTLV
3891
ESSTN
3896
VEMIL
3901
KFFDM
3906
FLKLK
3911
DLTSS
3916
DTFKE
3921
YDPDG
3926
KGIIS
3931
KKEFQ
3936
KAMEG
3941
QKQYT
3946
QSEID
3951
FLLSC
3956
AEADE
3961
NDMFN
3966
YVDFV
3971
DRFHE
3976
PAKDI
3981
GFNVA
3986
VLLTN
3991
LSEHM
3996
PNDSR
4001
LKCLL
4006
DPAES
4011
VLNYF
4016
EPYLG
4021
RIEIM
4026
GGAKK
4031
IERVY
4036
FEISE
4041
SSRTQ
4046
WEKPQ
4051
VKESK
4056
RQFIF
4061
DVVNE
4066
GGEQE
4071
KMELF
4076
VNFCE
4081
DTIFE
4086
MQLAS
4091
QISES
4096
DSADR
4101
PEEEE
4106
EDEDS
4111
SYVLE
4116
IAGEE
4121
EEDGS
4126
LEPAS
4131
AFAMA
4136
CASVK
4141
RNVTD
4146
FLKRA
4151
TLKNL
4156
RKQYR
4161
NVKKM
4166
TAKEL
4171
VKVLF
4176
SFFWM
4181
LFVGL
4186
FQLLF
4191
TILGG
4196
IFQIL
4201
WSTVF
4206
GGGLV
4211
EGAKN
4216
IRVTK
4221
ILGDM
4226
PDPTQ
4231
FGIHD
4236
DTMEA
4241
ERAEV
4246
MEPGI
4251
TTELV
4256
HFIKG
4261
EKGDT
4266
DIMSD
4271
LFGLH
4276
PKKEG
4281
SLKHG
4286
PEVGL
4291
GDLSE
4296
IIGKD
4301
EPPTL
4306
ESTVQ
4311
KKRKA
4316
QAAEM
4321
KAANE
4326
AEGKV
4331
ESEKA
4336
DMEDG
4341
EKEDK
4346
DKEEE
4351
QAEYL
4356
WTEVT
4361
KKKKR
4366
RCGQK
4371
VEKPE
4376
AFTAN
4381
FFKGL
4386
EIYQT
4391
KLLHY
4396
LARNF
4401
YNLRF
4406
LALFV
4411
AFAIN
4416
FILLF
4421
YKVTE
4426
EPLEE
4431
ETEDV
4436
ANLWN
4441
SFNDE
4446
EEEEA
4451
MVFFV
4456
LQEST
4461
GYMAP
4466
TLRAL
4471
AIIHT
4476
IISLV
4481
CVVGY
4486
YCLKV
4491
PLVVF
4496
KREKE
4501
IARKL
4506
EFDGL
4511
YITEQ
4516
PSEDD
4521
IKGQW
4526
DRLVI
4531
NTPSF
4536
PNNYW
4541
DKFVK
4546
RKVIN
4551
KYGDL
4556
YGAER
4561
IAELL
4566
GLDKN
4571
ALDFS
4576
PVEET
4581
KAEAA
4586
SLVSW
4591
LSSID
4596
MKYHI
4601
WKLGV
4606
VFTDN
4611
SFLYL
4616
AWYTT
4621
MSVLG
4626
HYNNF
4631
FFAAH
4636
LLDIA
4641
MGFKT
4646
LRTIL
4651
SSVTH
4656
NGKQL
4661
VLTVG
4666
LLAVV
4671
VYLYT
4676
VVAFN
4681
FFRKF
4686
YNKSE
4691
DDDEP
4696
DMKCD
4701
DMMTC
4706
YLFHM
4711
YVGVR
4716
AGGGI
4721
GDEIE
4726
DPAGD
4731
PYEMY
4736
RIVFD
4741
ITFFF
4746
FVIVI
4751
LLAII
4756
QGLII
4761
DAFGE
4766
LRDQQ
4771
EQVRE
4776
DMETK
4781
CFICG
4786
IGNDY
4791
FDTTP
4796
HGFET
4801
HTLQE
4806
HNLAN
4811
YLFFL
4816
MYLIN
4821
KDETE
4826
HTGQE
4831
SYVWK
4836
MYQER
4841
CWDFF
4846
PAGDC
4851
FRKQY
4856
EDQLG
4861
Mutation Information
DNA mutation:
None
Peptide Range:
4321 ~ 4345
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"QAAEMKAANEAEGKVESEKADMEDG
||||||||||||.||||||||||||
Mutant:
QAAEMKAANEAERKVESEKADMEDG"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) RYR3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay