Immunogenicity 1492

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
ADAM23
Transcript ID
ENST00000264377
HLA INFO
B*27:03
TCR INFO

No TCR info found!

T cell Tumor cell B*27:03
sequence
Full length protein sequence (832 aa)
MKPPG
1
SSSRQ
6
PPLAG
11
CSLAG
16
ASCGP
21
QRGPA
26
GSVPA
31
SAPAR
36
TPPCR
41
LLLVL
46
LLLPP
51
LAASS
56
RPRAW
61
GAAAP
66
SAPHW
71
NETAE
76
KNLGV
81
LADED
86
NTLQQ
91
NSSSN
96
ISYSN
101
AMQKE
106
ITLPS
111
RLIYY
116
INQDS
121
ESPYH
126
VLDTK
131
ARHQQ
136
KHNKA
141
VHLAQ
146
ASFQI
151
EAFGS
156
KFILD
161
LILNN
166
GLLSS
171
DYVEI
176
HYENG
181
KPQYS
186
KGGEH
191
CYYHG
196
SIRGV
201
KDSKV
206
ALSTC
211
NGLHG
216
MFEDD
221
TFVYM
226
IEPLE
231
LVHDE
236
KSTGR
241
PHIIQ
246
KTLAG
251
QYSKQ
256
MKNLT
261
MERGD
266
QWPFL
271
SELQW
276
LKRRK
281
RAVNP
286
SRGIF
291
EEMKY
296
LELMI
301
VNDHK
306
TYKKH
311
RSSHA
316
HTNNF
321
AKSVV
326
NLVDS
331
IYKEQ
336
LNTRV
341
VLVAV
346
ETWTE
351
KDQID
356
ITTNP
361
VQMLH
366
EFSKY
371
RQRIK
376
QHADA
381
VHLIS
386
RVTFH
391
YKRSS
396
LSYFG
401
GVCSR
406
TRGVG
411
VNEYG
416
LPMAV
421
AQVLS
426
QSLAQ
431
NLGIQ
436
WEPSS
441
RKPKC
446
DCTES
451
WGGCI
456
MEETG
461
VSHSR
466
KFSKC
471
SILEY
476
RDFLQ
481
RGGGA
486
CLFNR
491
PTKLF
496
EPTEC
501
GNGYV
506
EAGEE
511
CDCGF
516
HVECY
521
GLCCK
526
KCSLS
531
NGAHC
536
SDGPC
541
CNNTS
546
CLFQP
551
RGYEC
556
RDAVN
561
ECDIT
566
EYCTG
571
DSGQC
576
PPNLH
581
KQDGY
586
ACNQN
591
QGRCY
596
NGECK
601
TRDNQ
606
CQYIW
611
GTKAA
616
GSDKF
621
CYEKL
626
NTEGT
631
EKGNC
636
GKDGD
641
RWIQC
646
SKHDV
651
FCGFL
656
LCTNL
661
TRAPR
666
IGQLQ
671
GEIIP
676
TSFYH
681
QGRVI
686
DCSGA
691
HVVLD
696
DDTDV
701
GYVED
706
GTPCG
711
PSMMC
716
LDRKC
721
LQIQA
726
LNMSS
731
CPLDS
736
KGKVC
741
SGHGV
746
CSNEA
751
TCICD
756
FTWAG
761
TDCSI
766
RDPVR
771
NLHPP
776
KDEGP
781
KGPSA
786
TNLII
791
GSIAG
796
AILVA
801
AIVLG
806
GTGWG
811
FKNVK
816
KRRFD
821
PTQQG
826
PI
831
Mutation Information
DNA mutation:
None
Peptide Range:
366 ~ 390
Mut AA position:
378 (13 in Wild Type peptide)
Alignment
Wild Type:
"VQMLHEFSKYRQRIKQHADAVHLIS
||||||||||||.||||||||||||
Mutant:
VQMLHEFSKYRQCIKQHADAVHLIS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ADAM23

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay