Immunogenicity 15085
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DLEC1
Transcript ID
uc010hgv.1
HLA INFO
C*02:02
TCR INFO
No TCR info found!
Full length protein sequence (1758 aa)
METRS
1
SKTRR
6
SLASR
11
TNECQ
16
GTMWA
21
PTSPP
26
AGSSS
31
PSQPT
36
WKSSL
41
YSSLA
46
YSEAF
51
HYSFA
56
ARPRR
61
LTQLA
66
LAQRP
71
EPQLL
76
RLRPS
81
SLRTQ
86
DISHL
91
LTGVF
96
RNLYS
101
AEVIG
106
DEVSA
111
SLIKA
116
RGSEN
121
ERHEE
126
FVDQL
131
QQIRE
136
LYKQR
141
LDEFE
146
MLERH
151
ITQAQ
156
ARAIA
161
ENERV
166
MSQAG
171
VQDLE
176
SLVRL
181
PPVKS
186
VSRWC
191
IDSEL
196
LRKHH
201
LISPE
206
DYYTD
211
TVPFH
216
SAPKG
221
ISLPG
226
CSKLT
231
FSCEK
236
RSVQK
241
KELNK
246
KLEDS
251
CRKKL
256
AEFED
261
ELDHT
266
VDSLT
271
WNLTP
276
KAKER
281
TREPL
286
KKASQ
291
PRNKN
296
WMNHL
301
RVPQR
306
ELDRL
311
LLARM
316
ESRNH
321
FLKNP
326
RFFPP
331
NTRYG
336
GKSLV
341
FPPKK
346
PAPIG
351
EFQST
356
EPEQS
361
CADTP
366
VFLAK
371
PPIGF
376
FTDYE
381
IGPVY
386
EMVIA
391
LQNTT
396
TTSRY
401
LRVLP
406
PSTPY
411
FALGL
416
GMFPG
421
KGGMV
426
APGMT
431
CQYIV
436
QFFPD
441
CLGDF
446
DDFIL
451
VETQS
456
AHTLL
461
IPLQA
466
RRPPP
471
VLTLS
476
PVLDC
481
GYCLI
486
GGVKM
491
TRFIC
496
KNVGF
501
SVGRF
506
CIMPK
511
TSWPP
516
LSFKA
521
IATVG
526
FVEQP
531
PFGIL
536
PSVFE
541
LAPGH
546
AILVE
551
VLFSP
556
KSLGK
561
AEQTF
566
IIMCD
571
NCQIK
576
ELVTI
581
GIGQL
586
IALDL
591
IYISG
596
EKSQP
601
DPGEL
606
TDLTA
611
QHFIR
616
FEPEN
621
LRSTA
626
RKQLI
631
IRNAT
636
HVELA
641
FYWQI
646
MKPNL
651
QPLMP
656
GETFS
661
MDSIK
666
CYPDK
671
ETAFS
676
IMPRK
681
GVLSP
686
HTDHE
691
FILSF
696
SPHEL
701
RDFHS
706
VLQMV
711
LEEVP
716
EPVSS
721
EAESL
726
GHSSY
731
SVDDV
736
IVLEI
741
EVKGS
746
VEPFQ
751
VLLEP
756
YALII
761
PGENY
766
IGINV
771
KKAFK
776
MWNNS
781
KSPIR
786
YLWGK
791
ISDCH
796
IIEVE
801
PGTGV
806
IEPSE
811
VGDFE
816
LNFTG
821
GVPGP
826
TSQDL
831
LCEIE
836
DSPSP
841
VVLHI
846
EAVFK
851
GPALI
856
INVSA
861
LQFGL
866
LRLGQ
871
KATNS
876
IQIRN
881
VSQLP
886
ATWRM
891
KESPV
896
SLQER
901
PEDVS
906
PFDIE
911
PSSGQ
916
LHSLG
921
ECRVD
926
ITLEA
931
LHCQH
936
LETVL
941
ELEVE
946
NGAWS
951
YLPVY
956
AEVQK
961
PHVYL
966
QSSQV
971
EVRNL
976
YLGVP
981
TKTTI
986
TLING
991
TLLPT
996
QFHWG
1001
KLLGH
1006
QAEFC
1011
MVTVS
1016
PKHGL
1021
LGPSE
1026
ECQLK
1031
LELTA
1036
HTQEE
1041
LTHLA
1046
LPCHV
1051
SGMKK
1056
PLVLG
1061
ISGKP
1066
QGLQV
1071
AITIS
1076
KESSD
1081
CSVFS
1086
TEQWP
1091
GHPKE
1096
LRLDF
1101
GSAVP
1106
LRTRV
1111
TRQLI
1116
LTNRS
1121
PIRTR
1126
FSLKF
1131
EYFGS
1136
PQNSL
1141
SKKTS
1146
LPNMP
1151
PALLK
1156
TVRMQ
1161
EHLAK
1166
REQLD
1171
FMESM
1176
LSHGK
1181
GAAFF
1186
PHFSQ
1191
GMLGP
1196
YQQLC
1201
IDITG
1206
CANMW
1211
GEYWD
1216
NLICT
1221
VGDLL
1226
PEVIP
1231
VHMAA
1236
VGCPI
1241
SSLRT
1246
TSYTI
1251
DQAQK
1256
EPAMR
1261
FGTQV
1266
SGGDT
1271
VTRTL
1276
RLNNS
1281
SPCDI
1286
RLDWE
1291
TYVPE
1296
DKEDR
1301
LVELL
1306
VFYGP
1311
PFPLR
1316
DQAGN
1321
ELVCP
1326
DTPEG
1331
GCLLW
1336
SPGPS
1341
SSSEF
1346
SHETD
1351
SSVEG
1356
SSSAS
1361
NRVAQ
1366
KLISV
1371
ILQAH
1376
EGVPS
1381
GHLYC
1386
ISPKQ
1391
VVVPA
1396
GGSST
1401
IYISF
1406
TPMVL
1411
SPEIL
1416
HKVEC
1421
TGYAL
1426
GFMSL
1431
DSKVE
1436
REIPG
1441
KRHRL
1446
QDFAV
1451
GPLKL
1456
DLHSY
1461
VRPAQ
1466
LSVEL
1471
DYGGS
1476
MEFQC
1481
QASDL
1486
IPEQP
1491
CSGVL
1496
SELVT
1501
THHLK
1506
LTNTT
1511
EIPHY
1516
FRLMV
1521
SRPFS
1526
VSQDG
1531
ASQDH
1536
RAPGP
1541
GQKQE
1546
CEEET
1551
ASADK
1556
QLVLQ
1561
AQENM
1566
LVNVS
1571
FSLSL
1576
ELLSY
1581
QKLPA
1586
DQTLP
1591
GVDIQ
1596
QSASG
1601
EREMV
1606
FTQNL
1611
LLEYT
1616
NQTTQ
1621
VVPLR
1626
AVVAV
1631
PELQL
1636
STSWV
1641
DFGTC
1646
FVSQQ
1651
RVREV
1656
YLMNL
1661
SGCRS
1666
YWTML
1671
MGQQE
1676
PAKAA
1681
VAFRV
1686
SPNSG
1691
LLEAR
1696
SANAP
1701
PTSIA
1706
LQVFF
1711
TARSS
1716
ELYES
1721
TMVVE
1726
GVLGE
1731
KSCTL
1736
RLRGQ
1741
GSYDE
1746
RYMLP
1751
HQP
1756
Mutation Information
DNA mutation:
None
Peptide Range:
1116 ~ 1140
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"TRQLILTNRSPIRTRFSLKFEYFGS
||||||||||||.||||||||||||
Mutant:
TRQLILTNRSPIQTRFSLKFEYFGS"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) DLEC1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay