Immunogenicity 1513
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
CCAR2
Transcript ID
ENST00000520861
HLA INFO
B*14:02
TCR INFO
No TCR info found!
Full length protein sequence (598 aa)
MLFVD
1
DMAEP
6
RETPE
11
HPLKQ
16
IKFLL
21
GRKEE
26
EAVLV
31
GGEWS
36
PSLDG
41
LDPQA
46
DPQVL
51
VRTAI
56
RCAQA
61
QTGID
66
LSGCT
71
KWWRF
76
AEFQY
81
LQPGP
86
PRRLQ
91
TVVVY
96
LPDVW
101
TIMPT
106
LEEWE
111
ALCQQ
116
KAAEA
121
APPTQ
126
EAQGE
131
TEPTE
136
QAPDA
141
LEQAA
146
DTSRR
151
NAETP
156
EATTQ
161
QETDT
166
DLPEA
171
PPPPL
176
EPAVI
181
ARPGC
186
VNLSL
191
HGIVE
196
DRRPK
201
ERISF
206
EVMVL
211
AELFL
216
EMLQR
221
DFGYR
226
VYKML
231
LSLPE
236
KVVSP
241
PEPEK
246
EEAAK
251
EEATK
256
EEEAI
261
KEEVV
266
KEPKD
271
EAQNE
276
GPATE
281
SEAPL
286
KEDGL
291
LPKPL
296
SSGGE
301
EEEKP
306
RGEAS
311
EDLCE
316
MALDP
321
ELLLL
326
RDDGE
331
EEFAG
336
AKLED
341
SEVRS
346
VASNQ
351
SEMEF
356
SSLQD
361
MPKEL
366
DPSAV
371
LPLDC
376
LLAFV
381
FFDAN
386
WCGYL
391
HRRDL
396
ERILL
401
TLGIR
406
LSAEQ
411
AKQLV
416
SRVVT
421
QNICQ
426
YRSLQ
431
YSRQE
436
GLDGG
441
LPEEV
446
LFGNL
451
DLLPP
456
PGKST
461
KPGAA
466
PTEHK
471
ALVSH
476
NGSLI
481
NVGSL
486
LQRAE
491
QQDSG
496
RLYLE
501
NKIHT
506
LELKL
511
EESHN
516
RFSAT
521
EVTNK
526
TLAAE
531
MQELR
536
VRLAE
541
AEETA
546
RTAER
551
QKSQL
556
QRLLQ
561
ELRRR
566
LTPLQ
571
LEIQR
576
VVEKV
581
RWGWT
586
RRQHS
591
SFP
596
Mutation Information
DNA mutation:
None
Peptide Range:
470 ~ 494
Mut AA position:
482 (13 in Wild Type peptide)
Alignment
Wild Type:
"APTEHKALVSHNGSLINVGSLLQRA
||||||||||||.||||||||||||
Mutant:
APTEHKALVSHNASLINVGSLLQRA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) CCAR2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay