Immunogenicity 15144
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TRIML2
Transcript ID
uc011cle.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (462 aa)
MSKRL
1
SPQLQ
6
HNITE
11
DAYCE
16
THLEP
21
TRLFC
26
DVDQI
31
TLCSK
36
CFQSQ
41
EHKHH
46
MVCGI
51
QEAAE
56
NYRKL
61
FQEIL
66
NTSRE
71
KLEAA
76
KSILT
81
DEQER
86
MAMIQ
91
EEEQN
96
FKKMI
101
ESEYS
106
MRLRL
111
LNEEC
116
EQNLQ
121
RQQEC
126
ISDLN
131
LRETL
136
LNQAI
141
KLATE
146
LEEMF
151
QEMLQ
156
RLGRV
161
GRENM
166
EKLKE
171
SEARA
176
SEQVR
181
SLLKL
186
IVELE
191
KKCGE
196
GTLAL
201
LKCLD
206
LEIRP
211
PELRE
216
MNFCC
221
AEATQ
226
SMNAK
231
YSLER
236
SKSLL
241
LEHLE
246
PAHIT
251
DLSLC
256
HIRGL
261
SSMFR
266
VLQRH
271
LTLDP
276
ETAHP
281
CLALS
286
EDLRT
291
MRLRH
296
GQQDG
301
AGNPE
306
RLDFS
311
AMVLA
316
AESFT
321
SGRHY
326
WEVDV
331
EKATR
336
WQVGI
341
YHGSA
346
DAKGS
351
TARAS
356
GEKVL
361
LTGSV
366
MGTEW
371
TLWVF
376
PPLKR
381
LFLEK
386
KLDTV
391
GVFLD
396
CEHGQ
401
ISFYN
406
VTEMS
411
LIYNF
416
SHCAF
421
QGALR
426
PVFSL
431
CIPNG
436
DTSPD
441
SLTIL
446
QHGPS
451
CDATV
456
SP
461
Mutation Information
DNA mutation:
None
Peptide Range:
428 ~ 452
Mut AA position:
365 (13 in Wild Type peptide)
Alignment
Wild Type:
"ALRPVFSLCIPNGDTSPDSLTILQH
||||||||||||.||||||||||||
Mutant:
ALRPVFSLCIPNRDTSPDSLTILQH"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) TRIML2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay