Immunogenicity 1517

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SNX24
Transcript ID
ENST00000395451
HLA INFO
DRB*07:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*07:01
sequence
Full length protein sequence (202 aa)
MEVYI
1
PSFRY
6
EESDL
11
ERGYT
16
VVIVW
21
HRAFQ
26
TKMES
31
YEVIV
36
LEIAF
41
SNGRL
46
TYQVF
51
KIEVL
56
MNGRK
61
HFVEK
66
RYSEF
71
HALHK
76
KLKKC
81
IKTPE
86
IPSKH
91
VRNWV
96
PKVLE
101
QRRQG
106
LETYL
111
QAVIL
116
ENEEL
121
PKLFL
126
DFLNV
131
RHLPS
136
LPKAE
141
SCGSF
146
DETES
151
EESSK
156
LSHQP
161
VLLFL
166
RDPYV
171
LPAAS
176
DFPNV
181
VIEGV
186
LHGIF
191
YPHLQ
196
PR
201
Mutation Information
DNA mutation:
None
Peptide Range:
46 ~ 70
Mut AA position:
58 (13 in Wild Type peptide)
Alignment
Wild Type:
"SNGRLTYQVFKIEVLMNGRKHFVEK
||||||||||||.||||||||||||
Mutant:
SNGRLTYQVFKIQVLMNGRKHFVEK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000064652

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay