Immunogenicity 15240

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
VPS13B
Transcript ID
uc003yiv.4
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (4022 aa)
MLESY
1
VTPIL
6
MSYVN
11
RYIKN
16
LKPSD
21
LQLSL
26
WGGDV
31
VLSKL
36
ELKLD
41
VLEQE
46
LKLPF
51
TFLSG
56
HIHEL
61
RIHVP
66
WTKLG
71
SEPVV
76
ITINT
81
MECIL
86
KLKDG
91
IQDDH
96
ESCGS
101
NSTNR
106
STAES
111
TKSSI
116
KPRRM
121
QQAAP
126
TDPDL
131
PPGYV
136
QSLIR
141
RVVNN
146
VNIVI
151
NNLIL
156
KYVED
161
DIVLS
166
VNITS
171
AECYT
176
VGELW
181
DRAFM
186
DISAT
191
DLVLR
196
KVINF
201
SDCTV
206
CLDKR
211
NASGK
216
IEFYQ
221
DPLLY
226
KCSFR
231
TRLHF
236
TYENL
241
NSKMP
246
SVIKI
251
HTLVE
256
SLKLS
261
ITDQQ
266
LPMFI
271
RIMQL
276
GIALY
281
YGEIG
286
NFKEG
291
EIEDL
296
TCHNK
301
DMLGN
306
ITGSE
311
DETRI
316
DMQYP
321
AQHKG
326
QELYS
331
QQDEE
336
QPQGW
341
VSWAW
346
SFVPA
351
IVSYD
356
DGEED
361
FVGND
366
PASTM
371
HQQKA
376
QTLKD
381
PIVSI
386
GFYCT
391
KATVT
396
FKLTE
401
MQVES
406
SYYSP
411
QKVKS
416
KEVLC
421
WEQEG
426
TTVEA
431
LMMGE
436
PFFDC
441
QIGFV
446
GCRAM
451
CLKGI
456
MGVKD
461
FEENM
466
NRSET
471
EACFF
476
ICGDN
481
LSTKG
486
FTYLT
491
NSLFD
496
YRSPE
501
NNGTR
506
AEFIL
511
DSTHH
516
KETYT
521
EIAGM
526
QRFGA
531
FYMDY
536
LYTME
541
NTSGK
546
GSTNQ
551
QDFSS
556
GKSED
561
LGTVQ
566
EKSTK
571
SLVIG
576
PLDFR
581
LDSSA
586
VHRIL
591
KMIVC
596
ALEHE
601
YEPYS
606
RLKSD
611
IKDEN
616
ETILN
621
PEEVA
626
LLEEY
631
IPTRH
636
TSVTL
641
LKCTC
646
TISMA
651
EFNLL
656
DHLLP
661
VIMGE
666
KNSSN
671
FMNTT
676
NFQSL
681
RPLPS
686
IRILV
691
DKINL
696
EHSVP
701
MYAEQ
706
LVHVV
711
SSLTQ
716
PSDNL
721
LHYCY
726
VHCYL
731
KIFGF
736
QAGLT
741
SLDCS
746
GSYCL
751
PVPVI
756
PSFST
761
ALYGK
766
LLKLP
771
TCWTK
776
RSQIA
781
ITEGI
786
FELPN
791
LTIQA
796
TRAQT
801
LLLQA
806
IYQSW
811
SHLGN
816
VSSSA
821
VIEAL
826
INEIF
831
LSIGV
836
KSKNP
841
LPTLE
846
GSIQN
851
VELKY
856
CSTSL
861
VKCAS
866
GTMGS
871
IKICA
876
KAPVD
881
SGKEK
886
LIPLL
891
QGPSD
896
TKDLH
901
STKWL
906
NESRK
911
PESLL
916
APDLM
921
AFTIQ
926
VPQYI
931
DYCHN
936
SGAVL
941
LCSIQ
946
GLAVN
951
IDPIL
956
YTWLI
961
YQPQK
966
RTSRH
971
MQQQP
976
VVAVP
981
LVMPV
986
CRRKE
991
DEVSI
996
GSAPL
1001
AKQQS
1006
YQASE
1011
YASSP
1016
VKTKT
1021
VTESR
1026
PLSVP
1031
VKAML
1036
NISES
1041
CRSPE
1046
ERMKE
1051
FIGIV
1056
WNAVK
1061
HLTLQ
1066
LEVQS
1071
CCVFI
1076
PNDSL
1081
PSPST
1086
IVSGD
1091
IPGTV
1096
RSWYH
1101
GQTSM
1106
PGTLV
1111
LCLPQ
1116
IKIIS
1121
AGHKY
1126
MEPLQ
1131
EIPFV
1136
IPRPI
1141
LEEGD
1146
AFPWT
1151
ISLHN
1156
FSIYT
1161
LLGKQ
1166
VTLCL
1171
VEPMG
1176
CTSTL
1181
AVTSQ
1186
KLLAT
1191
GPDTR
1196
HSFVV
1201
CLHVD
1206
LESLE
1211
IKCSN
1216
PQVQL
1221
FYELT
1226
DIMNK
1231
VWNKI
1236
QKRGN
1241
LNLSP
1246
TSPET
1251
MAGPV
1256
PTSPV
1261
RSSIG
1266
TAPPD
1271
TSTCS
1276
PSADI
1281
GTTTE
1286
GDSIQ
1291
AGEES
1296
PFSDS
1301
VTLEQ
1306
TTSNI
1311
GGTSG
1316
RVSLW
1321
MQWVL
1326
PKITI
1331
KLFAP
1336
DPENK
1341
GTEVC
1346
MVSEL
1351
EDLSA
1356
SIDVQ
1361
DVYTK
1366
VKCKI
1371
ESFNI
1376
DHYRS
1381
SLGEE
1386
CWSLG
1391
QCGGV
1396
FLSCT
1401
DKLNR
1406
RTLLV
1411
RPISK
1416
QDPFS
1421
NCSGF
1426
FPSTT
1431
TKLLD
1436
GTHQQ
1441
HGFLS
1446
LTYTK
1451
AVTKN
1456
VRHKL
1461
TSRNE
1466
RRSFH
1471
KLSEG
1476
LMDGS
1481
PHFLH
1486
EILLS
1491
AQAFD
1496
IVLYF
1501
PLLNA
1506
IASIF
1511
QAKLP
1516
KTQKE
1521
KRKSP
1526
GQPMR
1531
THTLT
1536
SRNLP
1541
LIYVN
1546
TSVIR
1551
IFIPK
1556
TEEMQ
1561
PTVEA
1566
NQAAK
1571
EDTVV
1576
LKIGS
1581
VAMAP
1586
QADNP
1591
LGRSV
1596
LRKDI
1601
YQRAL
1606
NLGIL
1611
RDPGS
1616
EIEDR
1621
QYQID
1626
LQSIN
1631
IGTAQ
1636
WHQLK
1641
PEKES
1646
VSGGV
1651
VTETE
1656
RNSQN
1661
PALEW
1666
NMASS
1671
IRRHQ
1676
ERRAI
1681
LTPVL
1686
TDFSV
1691
RITGA
1696
PAVIF
1701
TKVVS
1706
PENLH
1711
TEEIL
1716
VCGHS
1721
LEVNI
1726
TTNLD
1731
FFLSV
1736
AQVQL
1741
LHQLI
1746
VANMT
1751
GLEPS
1756
NKAAE
1761
ISKQE
1766
QKKVD
1771
IFDGG
1776
MAETS
1781
SRYSG
1786
AQDSG
1791
IGSDS
1796
VKIRI
1801
VQIEQ
1806
HSGAS
1811
QHRIA
1816
RPSRQ
1821
SSIVK
1826
NLNFI
1831
PFDIF
1836
ITASR
1841
ISLMT
1846
YSCMA
1851
LSKSK
1856
SQEQK
1861
NNEKT
1866
DKSSL
1871
NLPEV
1876
DSDVA
1881
KPNQA
1886
CISTV
1891
TAEDL
1896
LRSSI
1901
SFPSG
1906
KKIGV
1911
LSLES
1916
LHAST
1921
RSSAR
1926
QALGI
1931
TIVRQ
1936
PGRRG
1941
TGDLQ
1946
LEPFL
1951
YFIVS
1956
QPSLL
1961
LSCHH
1966
RKQRV
1971
EVSIF
1976
DAVLK
1981
GVASD
1986
YKCID
1991
PGKTL
1996
PEALD
2001
YCTVW
2006
LQTVP
2011
GEIDS
2016
KSGIP
2021
PSFIT
2026
LQIKD
2031
FLNGP
2036
ADVNL
2041
DISKP
2046
LKANL
2051
SFTKL
2056
DQINL
2061
FLKKI
2066
KNAHS
2071
LAHSE
2076
ETSAM
2081
SNTMV
2086
NKDDL
2091
PVSKY
2096
YRGKL
2101
SKPKI
2106
HGDGV
2111
QKISA
2116
QENMW
2121
RAVSC
2126
FQKIS
2131
VQTTQ
2136
IVISM
2141
ETVPH
2146
TSKPC
2151
LLASL
2156
SNLNG
2161
SLSVK
2166
ATQKV
2171
PGIIL
2176
GSSFL
2181
LSIND
2186
FLLKT
2191
SLKER
2196
SRILI
2201
GPCCA
2206
TANLE
2211
AKWCK
2216
HSGNP
2221
GPEQS
2226
IPKIS
2231
IDLRG
2236
GLLQV
2241
FWGQE
2246
HLNCL
2251
VLLHE
2256
LLNGY
2261
LNEEG
2266
NFEVQ
2271
VSEPV
2276
PQMSS
2281
PVEKN
2286
QTFKS
2291
EQSSD
2296
DLRTG
2301
LFQYV
2306
QDAES
2311
LKLPG
2316
VYEVL
2321
FYNET
2326
EDCPG
2331
MMLWR
2336
YPEPR
2341
VLTLV
2346
RITPV
2351
PFNTT
2356
EDPDI
2361
STADL
2366
GDVLQ
2371
VPCSL
2376
EYWDE
2381
LQKVF
2386
VAFRE
2391
FNLSE
2396
SKVCE
2401
LQLPD
2406
INLVN
2411
DQKKL
2416
VSSDL
2421
WRIVL
2426
NSSQN
2431
GADDQ
2436
SSASE
2441
SGSQS
2446
TCDPL
2451
VTPTA
2456
LAACT
2461
RVDSC
2466
FTPWF
2471
VPSLC
2476
VSFQF
2481
AHLEF
2486
HLCHH
2491
LDQLG
2496
TAAPQ
2501
YLQPF
2506
VSDRN
2511
MPSEL
2516
EYMIV
2521
SFREP
2526
HMYLR
2531
QWNNG
2536
SVCQE
2541
IQFLA
2546
QADCK
2551
LLECR
2556
NVTMQ
2561
SVVKP
2566
FSIFG
2571
QMAVS
2576
SDVVE
2581
KLLDC
2586
TVIVD
2591
SVFVN
2596
LGQHV
2601
VHSLN
2606
TAIQA
2611
WQQNK
2616
CPEVE
2621
ELVFS
2626
HFVIC
2631
NDTQE
2636
TLRFG
2641
QVDTD
2646
ENILL
2651
ASLHS
2656
HQYSW
2661
RSHKS
2666
PQLLH
2671
ICIEG
2676
WGNWR
2681
WSEPF
2686
SVDHA
2691
GTFIR
2696
TIQYR
2701
GRTAS
2706
LIIKV
2711
QQLNG
2716
VQKQI
2721
IICGR
2726
QIICS
2731
YLSQS
2736
IELKV
2741
VQHYI
2746
GQDGQ
2751
AVVRE
2756
HFDCL
2761
TAKQK
2766
LPSYI
2771
LENNE
2776
LTELC
2781
VKAKG
2786
DEDWS
2791
RDVCL
2796
ESKAP
2801
EYSIV
2806
IQVPS
2811
SNSSI
2816
IYVWC
2821
TVLTL
2826
EPNSQ
2831
VQQRM
2836
IVFSP
2841
LFIMR
2846
SHLPD
2851
PIIIH
2856
LEKRS
2861
LGLSE
2866
TQIIP
2871
GKGQE
2876
KPLQN
2881
IEPDL
2886
VHHLT
2891
FQARE
2896
EYDPS
2901
DCAVP
2906
ISTSL
2911
IKQIA
2916
TKVHP
2921
GGTVN
2926
QILDE
2931
FYGPE
2936
KSLQP
2941
IWPYN
2946
KKDSD
2951
RNEQL
2956
SQWDS
2961
PMRVK
2966
LSIWK
2971
PYVRT
2976
LLIEL
2981
LPWAL
2986
LINES
2991
KWDLW
2996
LFEGE
3001
KIVLQ
3006
VPAGK
3011
IIIPP
3016
NFQEA
3021
FQIGI
3026
YWANT
3031
NTVHK
3036
SVAIK
3041
LVHNL
3046
TSPKW
3051
KDGGN
3056
GEVVT
3061
LDEEA
3066
FVDTE
3071
IRLGA
3076
FPGHQ
3081
KLCQF
3086
CISSM
3091
VQQGI
3096
QIIQI
3101
EDKTT
3106
IINNT
3111
PYQIF
3116
YKPQL
3121
SVCNP
3126
HSGKE
3131
YFRVP
3136
DSATF
3141
SICPG
3146
GEQPA
3151
MKSSS
3156
LPCWD
3161
LMPDI
3166
SQSVL
3171
DASLL
3176
QKQIM
3181
LGFSP
3186
APGAD
3191
SSQCW
3196
SLPAI
3201
VRPEF
3206
PRQSV
3211
AVPLG
3216
NFREN
3221
GFCTR
3226
AIVLT
3231
YQEHL
3236
GVTYL
3241
TLSED
3246
PSPRV
3251
IIHNR
3256
CPVKM
3261
LIKEN
3266
IKDIP
3271
KFEVY
3276
CKKIP
3281
SECSI
3286
HHELY
3291
HQISS
3296
YPDCK
3301
TKDLL
3306
PSLLL
3311
RVEPL
3316
DEVTT
3321
EWSDA
3326
IDINS
3331
QGTQV
3336
VFLTG
3341
FGYVY
3346
VDVVH
3351
QCGTV
3356
FITVA
3361
PEGKA
3366
GPILT
3371
NTNRA
3376
PEKIV
3381
TFKMF
3386
ITQLS
3391
LAVFD
3396
DLTHH
3401
KASAE
3406
LLRLT
3411
LDNIF
3416
LCVAP
3421
GAGPL
3426
PGEEP
3431
VAALF
3436
ELYCV
3441
EICCG
3446
DLQLD
3451
NQLYN
3456
KSNFH
3461
FAVLV
3466
CQGEK
3471
AEPIQ
3476
CSKMQ
3481
SLLIS
3486
NKELE
3491
EYKEK
3496
CFIKL
3501
CITLN
3506
EGKSI
3511
LCDIN
3516
EFSFE
3521
LKPAR
3526
LYVED
3531
TFVYY
3536
IKTLF
3541
DTYLP
3546
NSRLA
3551
GHSTH
3556
LSGGK
3561
QVLPM
3566
QVTQH
3571
ARALV
3576
NPVKL
3581
RKLVI
3586
QPVNL
3591
LVSIH
3596
ASLKL
3601
YIASD
3606
HTPLS
3611
FSVFE
3616
RGPIF
3621
TTARQ
3626
LVHAL
3631
AMHYA
3636
AGALF
3641
RAGWV
3646
VGSLD
3651
ILGSP
3656
ASLVR
3661
SIGNG
3666
VADFF
3671
RLPYE
3676
GLTRG
3681
PGAFV
3686
SGVSR
3691
GTTSF
3696
VKHIS
3701
KGTLT
3706
SITNL
3711
ATSLA
3716
RNMDR
3721
LSLDE
3726
EHYNR
3731
QEEWR
3736
RQLPE
3741
SLGEG
3746
LRQGL
3751
SRLGI
3756
SLLGA
3761
IAGIV
3766
DQPMQ
3771
NFQKT
3776
SEAQA
3781
SAGHK
3786
AKGVI
3791
SGVGK
3796
GIMGV
3801
FTKPI
3806
GGAAE
3811
LVSQT
3816
GYGIL
3821
HGAGL
3826
SQLPK
3831
QRHQP
3836
SDLHA
3841
DQAPN
3846
SHVKY
3851
VWKML
3856
QSLGR
3861
PEVHM
3866
ALDVV
3871
LVRGS
3876
GQEHE
3881
GCLLL
3886
TSEVL
3891
FVVSV
3896
SEDTQ
3901
QQAFP
3906
VTEID
3911
CAQDS
3916
KQNNL
3921
LTVQL
3926
KQPRV
3931
ACDVE
3936
VDGVR
3941
ERLSE
3946
QQYNR
3951
LVDYI
3956
TKTSC
3961
HLAPS
3966
CSSMQ
3971
IPCPV
3976
VAAEP
3981
PPSTV
3986
KTYHY
3991
LVDPH
3996
FAQVF
4001
LSKFT
4006
MVKNK
4011
ALRKG
4016
FP
4021
Mutation Information
DNA mutation:
None
Peptide Range:
3272 ~ 3296
Mut AA position:
3284 (13 in Wild Type peptide)
Alignment
Wild Type:
"KDIPKFEVYCKKIPSECSIHHELYH
||||||||||||..|||||||||||
Mutant:
KDIPKFEVYCKKMSSECSIHHELYH"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay