Immunogenicity 15280

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PLXND1
Transcript ID
NM_015103
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (1925 aa)
MAPRA
1
AGGAP
6
LSARA
11
AAASP
16
PPFQT
21
PPRCP
26
VPLLL
31
LLLLG
36
AARAG
41
ALEIQ
46
RRFPS
51
PTPTN
56
NFALD
61
GAAGT
66
VYLAA
71
VNRLY
76
QLSGA
81
NLSLE
86
AEAAV
91
GPVPD
96
SPLCH
101
APQLP
106
QASCE
111
HPRRL
116
TDNYN
121
KILQL
126
DPGQG
131
LVVVC
136
GSIYQ
141
GFCQL
146
RRRGN
151
ISAVA
156
VRFPP
161
AAPPA
166
EPVTV
171
FPSML
176
NVAAN
181
HPNAS
186
TVGLV
191
LPPAA
196
GAGGS
201
RLLVG
206
ATYTG
211
YGSSF
216
FPRNR
221
SLEDH
226
RFENT
231
PEIAI
236
RSLDT
241
RGDLA
246
KLFTF
251
DLNPS
256
DDNIL
261
KIKQG
266
AKEQH
271
KLGFV
276
SAFLH
281
PSDPP
286
PGAQS
291
YAYLA
296
LNSEA
301
RAGDK
306
ESQAR
311
SLLAR
316
ICLPH
321
GAGGD
326
AKKLT
331
ESYIQ
336
LGLQC
341
AGGAG
346
RGDLY
351
SRLVS
356
VFPAR
361
ERLFA
366
VFERP
371
QGSPA
376
ARAAP
381
AALCA
386
FRFAD
391
VRAAI
396
RAART
401
ACFVE
406
PAPDV
411
VAVLD
416
SVVQG
421
TGPAC
426
ERKLN
431
IQLQP
436
EQLDC
441
GAAHL
446
QHPLS
451
ILQPL
456
KATPV
461
FRAPG
466
LTSVA
471
VASVN
476
NYTAV
481
FLGTV
486
NGRLL
491
KINLN
496
ESMQV
501
VSRRV
506
VTVAY
511
GEPVH
516
HVMQF
521
DPADS
526
GYLYL
531
MTSHQ
536
MARVK
541
VAACN
546
VHSTC
551
GDCVG
556
AADAY
561
CGWCA
566
LETRC
571
TLQQD
576
CTNSS
581
QQHFW
586
TSASE
591
GPSRC
596
PAMTV
601
LPSEI
606
DVRQE
611
YPGMI
616
LQISG
621
SLPSL
626
SGMEM
631
ACDYG
636
NNIRT
641
VARVP
646
GPAFG
651
HQIAY
656
CNLLP
661
RDQFP
666
PFPPN
671
QDHVT
676
VEMSV
681
RVNGR
686
NIVKA
691
NFTIY
696
DCSRT
701
AQVYP
706
HTACT
711
SCLSA
716
QWPCF
721
WCSQQ
726
HSCVS
731
NQSRC
736
EASPN
741
PTSPQ
746
DCPRT
751
LLSPL
756
APVPT
761
GGSQN
766
ILVPL
771
ANTAF
776
FQGAA
781
LECSF
786
GLEEI
791
FEAVW
796
VNESV
801
VRCDQ
806
VVLHT
811
TRKSQ
816
VFPLS
821
LQLKG
826
RPARF
831
LDSPE
836
PMTVM
841
VYNCA
846
MGSPD
851
CSQCL
856
GREDL
861
GHLCM
866
WSDGC
871
RLRGP
876
LQPMA
881
GTCPA
886
PEIRA
891
IEPLS
896
GPLDG
901
GTLLT
906
IRGRN
911
LGRRL
916
SDVAH
921
GVWIG
926
GVACE
931
PLPDR
936
YTVSE
941
EIVCV
946
TGPAP
951
GPLSG
956
VVTVN
961
ASKEG
966
KSRDR
971
FSYVL
976
PLVHS
981
LEPTM
986
GPKAG
991
GTRIT
996
IHGND
1001
LHVGS
1006
ELQVL
1011
VNDTD
1016
PCTEL
1021
MRTDT
1026
SIACT
1031
MPEGA
1036
LPAPV
1041
PVCVR
1046
FERRG
1051
CVHGN
1056
LTFWY
1061
MQNPV
1066
ITAIS
1071
PRRSP
1076
VSGGR
1081
TITVA
1086
GERFH
1091
MVQNV
1096
SMAVH
1101
HIGRE
1106
PTLCK
1111
VLNST
1116
LITCP
1121
SPGAL
1126
SNASA
1131
PVDFF
1136
INGRA
1141
YADEV
1146
AVAEE
1151
LLDPE
1156
EAQRG
1161
SRFRL
1166
DYLPN
1171
PQFST
1176
AKREK
1181
WIKHH
1186
PGEPL
1191
TLVIH
1196
KEQDS
1201
LGLQS
1206
HEYRV
1211
KIGQV
1216
SCDIQ
1221
IVSDR
1226
IIHCS
1231
VNESL
1236
GAAVG
1241
QLPIT
1246
IQVGN
1251
FNQTI
1256
ATLQL
1261
GGSET
1266
AIIVS
1271
IVICS
1276
VLLLL
1281
SVVAL
1286
FVFCT
1291
KSRRA
1296
ERYWQ
1301
KTLLQ
1306
MEEME
1311
SQIRE
1316
EIRKG
1321
FAELQ
1326
TDMTD
1331
LTKEL
1336
NRSQG
1341
IPFLE
1346
YKHFV
1351
TRTFF
1356
PKCSS
1361
LYEER
1366
YVLPS
1371
QTLNS
1376
QGSSQ
1381
AQETH
1386
PLLGE
1391
WKIPE
1396
SCRPN
1401
MEEGI
1406
SLFSS
1411
LLNNK
1416
HFLIV
1421
FVHAL
1426
EQQKD
1431
FAVRD
1436
RCSLA
1441
SLLTI
1446
ALHGK
1451
LEYYT
1456
SIMKE
1461
LLVDL
1466
IDASA
1471
AKNPK
1476
LMLRR
1481
TESVV
1486
EKMLT
1491
NWMSI
1496
CMYSC
1501
LRETV
1506
GEPFF
1511
LLLCA
1516
IKQQI
1521
NKGSI
1526
DAITG
1531
KARYT
1536
LNEEW
1541
LLREN
1546
IEAKP
1551
RNLNV
1556
SFQGC
1561
GMDSL
1566
SVRAM
1571
DTDTL
1576
TQVKE
1581
KILEA
1586
FCKNV
1591
PYSQW
1596
PRAED
1601
VDLEW
1606
FASST
1611
QSYIL
1616
RDLDD
1621
TSVVE
1626
DGRKK
1631
LNTLA
1636
HYKIP
1641
EGASL
1646
AMSLI
1651
DKKDN
1656
TLGRV
1661
KDLDT
1666
EKYFH
1671
LVLPT
1676
DELAE
1681
PKKSH
1686
RQSHR
1691
KKVLP
1696
EIYLT
1701
RLLST
1706
KGTLQ
1711
KFLDD
1716
LFKAI
1721
LSIRE
1726
DKPPL
1731
AVKYF
1736
FDFLE
1741
EQAEK
1746
RGISD
1751
PDTLH
1756
IWKTN
1761
SLPLR
1766
FWVNI
1771
LKNPQ
1776
FVFDI
1781
DKTDH
1786
IDACL
1791
SVIAQ
1796
AFIDA
1801
CSISD
1806
LQLGK
1811
DSPTN
1816
KLLYA
1821
KEIPE
1826
YRKIV
1831
QRYYK
1836
QIQDM
1841
TPLSE
1846
QEMNA
1851
HLAEE
1856
SRKYQ
1861
NEFNT
1866
NVAMA
1871
EIYKY
1876
AKRYR
1881
PQIMA
1886
ALEAN
1891
PTARR
1896
TQLQH
1901
KFEQV
1906
VALME
1911
DNIYE
1916
CYSEA
1921
Mutation Information
DNA mutation:
None
Peptide Range:
1335 ~ 1359
Mut AA position:
134 (13 in Wild Type peptide)
Alignment
Wild Type:
"DLTKELNRSQGIPFLEYKHFVTRTF
||||||||||||.||||||||||||
Mutant:
DLTKELNRSQGISFLEYKHFVTRTF"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay