Immunogenicity 15303
Sample ID
patient2
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TRPM8
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1115 aa)
MSFRA
1
ARLSM
6
RNRRN
11
DTLDS
16
TRTLY
21
SSASR
26
STDLS
31
YSESD
36
LVNFI
41
QANFK
46
KRECV
51
FFTKD
56
SKATE
61
NVCKC
66
GYAQS
71
QHMEG
76
TQINQ
81
SEKWN
86
YKKHT
91
KEFPT
96
DAFGD
101
IQFET
106
LGKKG
111
KYIRL
116
SCDTD
121
AEILY
126
ELLTQ
131
HWHLK
136
TPNLV
141
ISVTG
146
GAKNF
151
ALKPR
156
MRKIF
161
SRLIY
166
IAQSK
171
GAWIL
176
TGGTH
181
YGLMK
186
YIGEV
191
VRDNT
196
ISRSS
201
EENIV
206
AIGIA
211
AWGMV
216
SNRDT
221
LIRNC
226
DAEGY
231
FLAQY
236
LMDDF
241
TRDPL
246
YILDN
251
NHTHL
256
LLVDN
261
GCHGH
266
PTVEA
271
KLRNQ
276
LEKYI
281
SERTI
286
QDSNY
291
GGKIP
296
IVCFA
301
QGGGK
306
ETLKA
311
INTSI
316
KNKIP
321
CVVVE
326
GSGQI
331
ADVIA
336
SLVEV
341
EDALT
346
SSAVK
351
EKLVR
356
FLPRT
361
VSRLP
366
EEETE
371
SWIKW
376
LKEIL
381
ECSHL
386
LTVIK
391
MEEAG
396
DEIVS
401
NAISY
406
ALYKA
411
FSTSE
416
QDKDN
421
WNGQL
426
KLLLE
431
WNQLD
436
LANDE
441
IFTND
446
RRWES
451
ADLQE
456
VMFTA
461
LIKDR
466
PKFVR
471
LFLEN
476
GLNLR
481
KFLTH
486
DVLTE
491
LFSNH
496
FSTLV
501
YRNLQ
506
IAKNS
511
YNDAL
516
LTFVW
521
KLVAN
526
FRRGF
531
RKEDR
536
NGRDE
541
MDIEL
546
HDVSP
551
ITRHP
556
LQALF
561
IWAIL
566
QNKKE
571
LSKVI
576
WEQTR
581
GCTLA
586
ALGAS
591
KLLKT
596
LAKVK
601
NDINA
606
AGESE
611
ELANE
616
YETRA
621
VELFT
626
ECYSS
631
DEDLA
636
EQLLV
641
YSCEA
646
WGGSN
651
CLELA
656
VEATD
661
QHFIA
666
QPGVQ
671
NFLSK
676
QWYGE
681
ISRDT
686
KNWKI
691
ILCLF
696
IIPLV
701
GCGFV
706
SFRKK
711
PVDKH
716
KKLLW
721
YYVAF
726
FTSPF
731
VVFSW
736
NVVFY
741
IAFLL
746
LFAYV
751
LLMDF
756
HSVPH
761
PPELV
766
LYSLV
771
FVLFC
776
DEVRQ
781
WYVNG
786
VNYFT
791
DLWNV
796
MDTLG
801
LFYFI
806
AGIVF
811
RLHSS
816
NKSSL
821
YSGRV
826
IFCLD
831
YIIFT
836
LRLIH
841
IFTVS
846
RNLGP
851
KIIML
856
QRMLI
861
DVFFF
866
LFLFA
871
VWMVA
876
FGVAR
881
QGILR
886
QNEQR
891
WRWIF
896
RSVIY
901
EPYLA
906
MFGQV
911
PSDVD
916
GTTYD
921
FAHCT
926
FTGNE
931
SKPLC
936
VELDE
941
HNLPR
946
FPEWI
951
TIPLV
956
CIYML
961
STNIL
966
LVNLL
971
VAMFG
976
YTVGT
981
VQENN
986
DQVWK
991
FQRYF
996
LVQEY
1001
CSRLN
1006
IPFPF
1011
IVFAY
1016
FYMVV
1021
KKCFK
1026
CCCKE
1031
KNMES
1036
SVCCF
1041
KNEDN
1046
ETLAW
1051
EGVMK
1056
ENYLV
1061
KINTK
1066
ANDTS
1071
EEMRH
1076
RFRQL
1081
DTKII
1086
LRNAD
1091
EQFCY
1096
RLLNE
1101
RFSDP
1106
WVHGG
1111
Mutation Information
DNA mutation:
None
Peptide Range:
172 ~ 180
Mut AA position:
174 (3 in Wild Type peptide)
Alignment
Wild Type:
"AQSKGAWIL
||.||||||
Mutant:
AQFKGAWIL"
Science, 2016
Targeting of cancer neoantigens with donor-derived T cell receptor repertoiresGene Name (from Reference) TRPM8
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
MoDCs
Assay
IFNg ELISPOT assay