Immunogenicity 15316
Sample ID
patient3
Response
Negative
Tumor Type
Melanoma
Gene Symbol
EIF2AK3
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1116 aa)
MERAI
1
SPGLL
6
VRALL
11
LLLLL
16
LGLAA
21
RTVAA
26
GRARG
31
LPAPT
36
AEAAF
41
GLGAA
46
AAPTS
51
ATRVP
56
AAGAV
61
AAAEV
66
TVEDA
71
EALPA
76
AAGEQ
81
EPRGP
86
EPDDE
91
TELRP
96
RGRSL
101
VIIST
106
LDGRI
111
AALDP
116
ENHGK
121
KQWDL
126
DVGSG
131
SLVSS
136
SLSKP
141
EVFGN
146
KMIIP
151
SLDGA
156
LFQWD
161
QDRES
166
METVP
171
FTVES
176
LLESS
181
YKFGD
186
DVVLV
191
GGKSL
196
TTYGL
201
SAYSG
206
KVRYI
211
CSALG
216
CRQWD
221
SDEME
226
QEEDI
231
LLLQR
236
TQKTV
241
RAVGP
246
RSGNE
251
KWNFS
256
VGHFE
261
LRYIP
266
DMETR
271
AGFIE
276
STFKP
281
NENTE
286
ESKII
291
SDVEE
296
QEAAI
301
MDIVI
306
KVSVA
311
DWKVM
316
AFSKK
321
GGHLE
326
WEYQF
331
CTPIA
336
SAWLL
341
KDGKV
346
IPISL
351
FDDTS
356
YTSND
361
DVLED
366
EEDIV
371
EAARG
376
ATENS
381
VYLGM
386
YRGQL
391
YLQSS
396
VRISE
401
KFPSS
406
PKALE
411
SVTNE
416
NAIIP
421
LPTIK
426
WKPLI
431
HSPSR
436
TPVLV
441
GSDEF
446
DKCLS
451
NDKFS
456
HEEYS
461
NGALS
466
ILQYP
471
YDNGY
476
YLPYY
481
KRERN
486
KRSTQ
491
ITVRF
496
LDNPH
501
YNKNI
506
RKKDP
511
VLLLH
516
WWKEI
521
VATIL
526
FCIIA
531
TTFIV
536
RRLFH
541
PHPHR
546
QRKES
551
ETQCQ
556
TENKY
561
DSVSG
566
EANDS
571
SWNDI
576
KNSGY
581
ISRYL
586
TDFEP
591
IQCLG
596
RGGFG
601
VVFEA
606
KNKVD
611
DCNYA
616
IKRIR
621
LPNRE
626
LAREK
631
VMREV
636
KALAK
641
LEHPG
646
IVRYF
651
NAWLE
656
APPEK
661
WQEKM
666
DEIWL
671
KDEST
676
DWPLS
681
SPSPM
686
DAPSV
691
KIRRM
696
DPFAT
701
KEHIE
706
IIAPS
711
PQRSR
716
SFSVG
721
ISCDQ
726
TSSSE
731
SQFSP
736
LEFSG
741
MDHED
746
ISESV
751
DAAYN
756
LQDSC
761
LTDCD
766
VEDGT
771
MDGND
776
EGHSF
781
ELCPS
786
EASPY
791
VRSRE
796
RTSSS
801
IVFED
806
SGCDN
811
ASSKE
816
EPKTN
821
RLHIG
826
NHCAN
831
KLTAF
836
KPTSS
841
KSSSE
846
ATLSI
851
SPPRP
856
TTLSL
861
DLTKN
866
TTEKL
871
QPSSP
876
KVYLY
881
IQMQL
886
CRKEN
891
LKDWM
896
NGRCT
901
IEERE
906
RSVCL
911
HIFLQ
916
IAEAV
921
EFLHS
926
KGLMH
931
RDLKP
936
SNIFF
941
TMDDV
946
VKVGD
951
FGLVT
956
AMDQD
961
EEEQT
966
VLTPM
971
PAYAR
976
HTGQV
981
GTKLY
986
MSPEQ
991
IHGNS
996
YSHKV
1001
DIFSL
1006
GLILF
1011
ELLYP
1016
FSTQM
1021
ERVRT
1026
LTDVR
1031
NLKFP
1036
PLFTQ
1041
KYPCE
1046
YVMVQ
1051
DMLSP
1056
SPMER
1061
PEAIN
1066
IIENA
1071
VFEDL
1076
DFPGK
1081
TVLRQ
1086
RSRSL
1091
SSSGT
1096
KHSRQ
1101
SNNSH
1106
SPLPS
1111
N
1116
Mutation Information
DNA mutation:
None
Peptide Range:
1004 ~ 1012
Mut AA position:
1009 (6 in Wild Type peptide)
Alignment
Wild Type:
"KVDIFSLGL
|||||.|||
Mutant:
KVDIFFLGL"
Science, 2016
Targeting of cancer neoantigens with donor-derived T cell receptor repertoiresGene Name (from Reference) EIF2AK3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
MoDCs
Assay
IFNg ELISPOT assay