Immunogenicity 15320

summary
Sample ID
patient2
Response
Negative
Tumor Type
Melanoma
Gene Symbol
BRWD3
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (1802 aa)
MAAAP
1
TQIEA
6
ELYYL
11
IARFL
16
QSGPC
21
NKSAQ
26
VLVQE
31
LEEHQ
36
LIPRR
41
LDWEG
46
KEHRR
51
SFEDL
56
VAANA
61
HIPPD
66
YLLKI
71
CERIG
76
PLLDK
81
EIPQS
86
VPGVQ
91
TLLGV
96
GRQSL
101
LRDAK
106
DCKST
111
LWNGS
116
AFAAL
121
HRGRP
126
PELPV
131
NYVKP
136
PNVVN
141
ITSAR
146
QLTGC
151
SRFGH
156
IFPSS
161
AYQHI
166
KMHKR
171
ILGHL
176
SSVYC
181
VAFDR
186
SGRRI
191
FTGSD
196
DCLVK
201
IWATD
206
DGRLL
211
ATLRG
216
HSAEI
221
SDMAV
226
NYENT
231
LIAAG
236
SCDKV
241
VRVWC
246
LRTCA
251
PVAVL
256
QGHSA
261
SITSI
266
QFCPS
271
TKGTN
276
RYLTS
281
TGADG
286
TICFW
291
QWHVK
296
TMKFR
301
DRPVK
306
FTERS
311
RPGVQ
316
ISCSS
321
FSSGG
326
MFITT
331
GSTDH
336
VIRIY
341
YLGSE
346
VPEKI
351
AELES
356
HTDKV
361
VAVQF
366
CNNGD
371
SLRFV
376
SGSRD
381
GTARI
386
WQYQQ
391
QEWKS
396
IVLDM
401
ATKMT
406
GNNLP
411
SGEDK
416
ITKLK
421
VTMVA
426
WDRYD
431
TTVIT
436
AVNNF
441
LLKVW
446
NSITG
451
QLLHT
456
LSGHD
461
DEVFV
466
LEAHP
471
FDQRI
476
ILSAG
481
HDGNI
486
FIWDL
491
DRGTK
496
IRNYF
501
NMIEG
506
QGHGA
511
VFDCK
516
FSPDG
521
NHFAC
526
TDSHG
531
HLLLF
536
GFGCS
541
KYYEK
546
IPDQM
551
FFHTD
556
YRPLI
561
RDANN
566
YVLDE
571
QTQQA
576
PHLMP
581
PPFLV
586
DVDGN
591
PHPTK
596
FQRLV
601
PGREN
606
CKDEQ
611
LIPQL
616
GYVAN
621
GDGEV
626
VEQVI
631
GQQTN
636
DQDES
641
ILDGI
646
IRELQ
651
REQDL
656
RLINE
661
GDVPH
666
LPVNR
671
AYSVN
676
GALRS
681
PNMDI
686
SSSPN
691
IRLRR
696
HSSQI
701
EGVRQ
706
MHNNA
711
PRSQM
716
ATERD
721
LMAWS
726
RRVVV
731
NELNN
736
GVSRV
741
QEECR
746
TAKGD
751
IEISL
756
YTVEK
761
KKKPS
766
YTTQR
771
NDYEP
776
SCGRS
781
LRRTQ
786
RKRQH
791
TYQTR
796
SNIEH
801
NSQAS
806
CQNSG
811
VQEDS
816
DSSSE
821
EDETV
826
GTSDA
831
SVEDP
836
VVEWQ
841
SESSS
846
SDSSS
851
EYSDW
856
TADAG
861
INLQP
866
PKRQT
871
RQTTR
876
KICSS
881
SDEEN
886
LKSLE
891
ERQKK
896
PKQTR
901
KKKGG
906
LVSIA
911
GEPNE
916
EWFAP
921
QWILD
926
TIPRR
931
SPFVP
936
QMGDE
941
LIYFR
946
QGHEA
951
YVRAV
956
RKSKI
961
YSVNL
966
QKQPW
971
NKMDL
976
REQEF
981
VKIVG
986
IKYEV
991
GPPTL
996
CCLKL
1001
AFLDP
1006
ISGKM
1011
TGESF
1016
SIKYH
1021
DMPDV
1026
IDFLV
1031
LHQFY
1036
NEAKE
1041
RNWQI
1046
GDRFR
1051
SIIDD
1056
AWWFG
1061
TVESQ
1066
QPFQP
1071
EYPDS
1076
SFQCY
1081
SVHWD
1086
NNERE
1091
KMSPW
1096
DMEPI
1101
PEGTA
1106
FPDEV
1111
GAGVP
1116
VSQEE
1121
LTALL
1126
YKPQE
1131
GEWGA
1136
HSRDE
1141
ECERV
1146
IQGIN
1151
HLLSL
1156
DFASP
1161
FAVPV
1166
DLSAY
1171
PLYCT
1176
VVAYP
1181
TDLNT
1186
IRRRL
1191
ENRFY
1196
RRISA
1201
LMWEV
1206
RYIEH
1211
NARTF
1216
NEPDS
1221
PIVKA
1226
AKIVT
1231
DVLLR
1236
FIGDQ
1241
SCTDI
1246
LDTYN
1251
KIKAE
1256
ERNST
1261
DAEED
1266
TEIVD
1271
LDSDG
1276
PGTSS
1281
GRRVK
1286
CRGRR
1291
QSLKC
1296
NPDAW
1301
KKQCK
1306
ELLSL
1311
IYERE
1316
DSEPF
1321
RQPAD
1326
LLSYP
1331
GHQEQ
1336
EGESS
1341
ESVVP
1346
ERQQD
1351
SSLSE
1356
DYQDV
1361
IDTPV
1366
DFSTV
1371
KETLE
1376
AGNYG
1381
SPLEF
1386
YKDVR
1391
QIFNN
1396
SKAYT
1401
SNKKS
1406
RIYSM
1411
MLRLS
1416
ALFES
1421
HIKNI
1426
ISEYK
1431
SAIQS
1436
QKRRR
1441
PRYRK
1446
RLRSS
1451
SSSLS
1456
SSGAP
1461
SPKGK
1466
QKQMK
1471
LQPKN
1476
DQNTS
1481
VSHAR
1486
TSSPF
1491
SSPVS
1496
DAAEG
1501
LSLYL
1506
LDDEP
1511
DGPFS
1516
SSSFG
1521
GYSRS
1526
GNSHD
1531
PGKAK
1536
SFRNR
1541
VLPVK
1546
QDHSL
1551
DGPLT
1556
NGDGR
1561
EPRTG
1566
IKRKL
1571
LSASE
1576
EDENM
1581
GGEDK
1586
EKKET
1591
KEKSH
1596
LSTSE
1601
SGELG
1606
SSLSS
1611
ESTCG
1616
SDSDS
1621
ESTSR
1626
TDQDY
1631
VDGDH
1636
DYSKF
1641
IQTRP
1646
KRKLR
1651
KQHGN
1656
GKRNW
1661
KTRGT
1666
GGRGR
1671
WGRWG
1676
RWSRG
1681
GRGRG
1686
GRGRG
1691
SRGRG
1696
GGGTR
1701
GRGRG
1706
RGGRG
1711
ASRGA
1716
TRAKR
1721
ARIAD
1726
DEFDT
1731
MFSGR
1736
FSRLP
1741
RIKTR
1746
NQGRR
1751
TVLYN
1756
DDSDN
1761
DNFVS
1766
TEDPL
1771
NLGTS
1776
RSGRV
1781
RKMTE
1786
KARVS
1791
HLMGW
1796
NY
1801
Mutation Information
DNA mutation:
None
Peptide Range:
1458 ~ 1467
Mut AA position:
1467 (10 in Wild Type peptide)
Alignment
Wild Type:
"SLSSSGAPSP
|||||||||.
Mutant:
SLSSSGAPSL"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

MoDCs

Assay

IFNg ELISPOT assay