Immunogenicity 15321
Sample ID
patient2
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ARHGEF12
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1544 aa)
MSGTQ
1
STITD
6
RFPLK
11
KPIRH
16
GSILN
21
RESPT
26
DKKQK
31
VERIA
36
SHDFD
41
PTDSS
46
SKKTK
51
SSSEE
56
SRSEI
61
YGLVQ
66
RCVII
71
QKDDN
76
GFGLT
81
VSGDN
86
PVFVQ
91
SVKED
96
GAAMR
101
AGVQT
106
GDRII
111
KVNGT
116
LVTHS
121
NHLEV
126
VKLIK
131
SGSYV
136
ALTVQ
141
GRPPG
146
SPQIP
151
LADSE
156
VEPSV
161
IGHMS
166
PIMTS
171
PHSPG
176
ASGNM
181
ERITS
186
PVLMG
191
EENNV
196
VHNQK
201
VEILR
206
KMLQK
211
EQERL
216
QLLQE
221
DYNRT
226
PAQRL
231
LKEIQ
236
EAKKH
241
IPQLQ
246
EQLSK
251
ATGSA
256
QDGAV
261
VTPSR
266
PLGDT
271
LTVSE
276
AETDP
281
GDVLG
286
RTDCS
291
SGDAS
296
RPSSD
301
NADSP
306
KSGPK
311
ERIYL
316
EENPE
321
KSETI
326
QDTDT
331
QSLVG
336
SPSTR
341
IAPHI
346
IGAED
351
DDFGT
356
EHEQI
361
NGQCS
366
CFQSI
371
ELLKS
376
RPAHL
381
AVFLH
386
HVVSQ
391
FDPAT
396
LLCYL
401
YSDLY
406
KHTNS
411
KETRR
416
IFLEF
421
HQFFL
426
DRSAH
431
LKVSV
436
PDEMS
441
ADLEK
446
RRPEL
451
IPEDL
456
HRHYI
461
QTMQE
466
RVHPE
471
VQRHL
476
EDFRQ
481
KRSMG
486
LTLAE
491
SELTK
496
LDAER
501
DKDRL
506
TLEKE
511
RTCAE
516
QIVAK
521
IEEVL
526
MTAQA
531
VEEDK
536
SSTMQ
541
YVILM
546
YMKHL
551
GVKVK
556
EPRNL
561
EHKRG
566
RIGFL
571
PKIKQ
576
SMKKD
581
KEGEE
586
KGKRR
591
GFPSI
596
LGPPR
601
RPSRH
606
DNSAI
611
GRAME
616
LQKAR
621
HPKHL
626
STPSS
631
VSPEP
636
QDSAK
641
LRQSG
646
LANEG
651
TDAGY
656
LPANS
661
MSSVA
666
SGASF
671
SQEGG
676
KENDT
681
GSKQV
686
GETSA
691
PGDTL
696
DGTPR
701
TLNTV
706
FDFPP
711
PPLDQ
716
VQEEE
721
CEVER
726
VTEHG
731
TPKPF
736
RKFDS
741
VAFGE
746
SQSED
751
EQFEN
756
DLETD
761
PPNWQ
766
QLVSR
771
EVLLG
776
LKPCE
781
IKRQE
786
VINEL
791
FYTER
796
AHVRT
801
LKVLD
806
QVFYQ
811
RVSRE
816
GILSP
821
SELRK
826
IFSNL
831
EDILQ
836
LHIGL
841
NEQMK
846
AVRKR
851
NETSV
856
IDQIG
861
EDLLT
866
WFSGP
871
GEEKL
876
KHAAA
881
TFCSN
886
QPFAL
891
EMIKS
896
RQKKD
901
SRFQT
906
FVQDA
911
ESNPL
916
CRRLQ
921
LKDII
926
PTQMQ
931
RLTKY
936
PLLLD
941
NIAKY
946
TEWPT
951
EREKV
956
KKAAD
961
HCRQI
966
LNYVN
971
QAVKE
976
AENKQ
981
RLEDY
986
QRRLD
991
TSSLK
996
LSEYP
1001
NVEEL
1006
RNLDL
1011
TKRKM
1016
IHEGP
1021
LVWKV
1026
NRDKT
1031
IDLYT
1036
LLLED
1041
ILVLL
1046
QKQDD
1051
RLVLR
1056
CHSKI
1061
LASTA
1066
DSKHT
1071
FSPVI
1076
KLSTV
1081
LVRQV
1086
ATDNK
1091
ALFVI
1096
SMSDN
1101
GAQIY
1106
ELVAQ
1111
TVSEK
1116
TVWQD
1121
LICRM
1126
AASVK
1131
EQSTK
1136
PIPLP
1141
QSTPG
1146
EGDND
1151
EEDPS
1156
KLKEE
1161
QHGIS
1166
VTGLQ
1171
SPDRD
1176
LGLES
1181
TLISS
1186
KPQSH
1191
SLSTS
1196
GKSEV
1201
RDLFV
1206
AERQF
1211
AKEQH
1216
TDGTL
1221
KEVGE
1226
DYQIA
1231
IPDSH
1236
LPVSE
1241
ERWAL
1246
DALRN
1251
LGLLK
1256
QLLVQ
1261
QLGLT
1266
EKSVQ
1271
EDWQH
1276
FPRYR
1281
TASQG
1286
PQTDS
1291
VIQNS
1296
ENIKA
1301
YHSGE
1306
GHMPF
1311
RTGTG
1316
DIATC
1321
YSPRT
1326
STESF
1331
APRDS
1336
VGLAP
1341
QDSQA
1346
SNILV
1351
MDHMI
1356
MTPEM
1361
PTMEP
1366
EGGLD
1371
DSGEH
1376
FFDAR
1381
EAHSD
1386
ENPSE
1391
GDGAV
1396
NKEEK
1401
DVNLR
1406
ISGNY
1411
LILDG
1416
YDPVQ
1421
ESSTD
1426
EEVAS
1431
SLTLQ
1436
PMTGI
1441
PAVES
1446
THQQQ
1451
HSPQN
1456
THSDG
1461
AISPF
1466
TPEFL
1471
VQQRW
1476
GAMEY
1481
SCFEI
1486
QSPSS
1491
CADSQ
1496
SQIME
1501
YIHKI
1506
EADLE
1511
HLKKV
1516
EESYT
1521
ILCQR
1526
LAGSA
1531
LTDKH
1536
SDKS
1541
Mutation Information
DNA mutation:
None
Peptide Range:
1466 ~ 1475
Mut AA position:
1468 (3 in Wild Type peptide)
Alignment
Wild Type:
"AISPFTPEFL
||.|||||||
Mutant:
AILPFTPEFL"
Science, 2016
Targeting of cancer neoantigens with donor-derived T cell receptor repertoiresGene Name (from Reference) ARHGEF12
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
MoDCs
Assay
IFNg ELISPOT assay