Immunogenicity 15337
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
DDX60 (FPKM: 6.2)
Transcript ID
ENST00000393743
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1712 aa)
MERNV
1
LTTFS
6
QEMSQ
11
LILNE
16
MPKAE
21
YSSLF
26
NDFVE
31
SEFFL
36
IDGDS
41
LLITC
46
ICEIS
51
FKPGQ
56
NLHFF
61
YLVER
66
YLVDL
71
ISKGG
76
QFTIV
81
FFKDA
86
EYAYF
91
NFPEL
96
LSLRT
101
ALILH
106
LQKNT
111
TIDVR
116
TTFSR
121
CLSKE
126
WGSFL
131
EESYP
136
YFLIV
141
ADEGL
146
NDLQT
151
QLFNF
156
LIIHS
161
WARKV
166
NVVLS
171
SGQES
176
DVLCL
181
YAYLL
186
PSMYR
191
HQIFS
196
WKNKQ
201
NIKDA
206
YTTLL
211
NQLER
216
FKLSA
221
LAPLF
226
GSLKW
231
NNITE
236
EAHKT
241
VSLLT
246
QVWPE
251
GSDIR
256
RVFCV
261
TSCSL
266
SLRMY
271
HRFLG
276
NREPS
281
SGQET
286
EIQQV
291
NSNCL
296
TLQEM
301
EDLCK
306
LHCLT
311
VVFLL
316
HLPLS
321
QRACA
326
RVITS
331
HWAED
336
MKPLL
341
QMKKW
346
CEYFI
351
LRNIH
356
TFEFW
361
NLNLI
366
HLSDL
371
NDELL
376
LKNIA
381
FYYEN
386
ENVKG
391
LHLNL
396
GDTIM
401
KDYEY
406
LWNTV
411
SKLVR
416
DFEVG
421
QPFPL
426
RTTKV
431
CFLEK
436
KPSPI
441
KDSSN
446
EMVPN
451
LGFIP
456
TSSFV
461
VDKFA
466
GDILK
471
DLPFL
476
KSDDP
481
IVTSL
486
VKQKE
491
FDELV
496
HWHSH
501
KPLSD
506
DYDRS
511
RCQFD
516
EKSRD
521
PRVLR
526
SVQKY
531
HVFQR
536
FYGNS
541
LETVS
546
SKIIV
551
TQTIK
556
SKKDF
561
SGPKS
566
KKAHE
571
TKAEI
576
IAREN
581
KKRLF
586
AREEQ
591
KEEQK
596
WNALS
601
FSIEE
606
QLKEN
611
LHSGI
616
KSLED
621
FLKSC
626
KSSCV
631
KLQVE
636
MVGLT
641
ACLKA
646
WKEHC
651
RSEEG
656
KTTKD
661
LSIAV
666
QVMKR
671
IHSLM
676
EKYSE
681
LLQED
686
DRQLI
691
ARCLK
696
YLGFD
701
ELASS
706
LHPAQ
711
DAEND
716
VKVKK
721
RNKYS
726
VGIGP
731
ARFQL
736
QYMGH
741
YLIRD
746
ERKDP
751
DPRVQ
756
DFIPD
761
TWQRE
766
LLDVV
771
DKNES
776
AVIVA
781
PTSSG
786
KTYAS
791
YYCME
796
KVLKE
801
SDDGV
806
VVYVA
811
PTKAL
816
VNQVA
821
ATVQN
826
RFTKN
831
LPSGE
836
VLCGV
841
FTREY
846
RHDAL
851
NCQVL
856
ITVPA
861
CFEIL
866
LLAPH
871
RQNWV
876
KKIRY
881
VIFDE
886
VHCLG
891
GEIGA
896
EIWEH
901
LLVMI
906
RCPFL
911
ALSAT
916
ISNPE
921
HLTEW
926
LQSVK
931
WYWKQ
936
EDKII
941
ENNTA
946
SKRHV
951
GRQAG
956
FPKDY
961
LQVKQ
966
SYKVR
971
LVLYG
976
ERYND
981
LEKHV
986
CSIKH
991
GDIHF
996
DHFHP
1001
CAALT
1006
TDHIE
1011
RYGFP
1016
PDLTL
1021
SPRES
1026
IQLYD
1031
AMFQI
1036
WKSWP
1041
RAQEL
1046
CPENF
1051
IHFNN
1056
KLVIK
1061
KMDAR
1066
KYEES
1071
LKAEL
1076
TSWIK
1081
NGNVE
1086
QARMV
1091
LQNLS
1096
PEADL
1101
SPENM
1106
ITMFP
1111
LLVEK
1116
LRKME
1121
KLPAL
1126
FFLFK
1131
LGAVE
1136
NAAES
1141
VSTFL
1146
KKKQE
1151
TKRPP
1156
KADKE
1161
AHVMA
1166
NKLRK
1171
VKKSI
1176
EKQKI
1181
IDEKS
1186
QKKTR
1191
NVDQS
1196
LIHEA
1201
EHDNL
1206
VKCLE
1211
KNLEI
1216
PQDCT
1221
YADQK
1226
AVDTE
1231
TLQKV
1236
FGRVK
1241
FERKG
1246
EELKA
1251
LAERG
1256
IGYHH
1261
SAMSF
1266
KEKQL
1271
VEILF
1276
RKGYL
1281
RVVTA
1286
TGTLA
1291
LGVNM
1296
PCKSV
1301
VFAQN
1306
SVYLD
1311
ALNYR
1316
QMSGR
1321
AGRRG
1326
QDLMG
1331
DVYFF
1336
DIPFP
1341
KIGKL
1346
IKSNV
1351
PELRG
1356
HFPLS
1361
ITLVL
1366
RLMLL
1371
ASKGD
1376
DPEDA
1381
KAKVL
1386
SVLKH
1391
SLLSF
1396
KQPRV
1401
MDMLK
1406
LYFLF
1411
SLQFL
1416
VKEGY
1421
LDQEG
1426
NPMGF
1431
AGLVS
1436
HLHYH
1441
EPSNL
1446
VFVSF
1451
LVNGL
1456
FHDLC
1461
QPTRK
1466
GSKHF
1471
SQDVM
1476
EKLVL
1481
VLAHL
1486
FGRRY
1491
FPPKF
1496
QDAHF
1501
EFYQS
1506
KVFLD
1511
DLPED
1516
FSDAL
1521
DEYNM
1526
KIMED
1531
FTTFL
1536
RIVSK
1541
LADMN
1546
QEYQL
1551
PLSKI
1556
KFTGK
1561
ECEDS
1566
QLVSH
1571
LMSCK
1576
EGRVA
1581
ISPFV
1586
CLSGN
1591
FDDDL
1596
LRLET
1601
PNHVT
1606
LGTIG
1611
VNRSQ
1616
APVLL
1621
SQKFD
1626
NRGRK
1631
MSLNA
1636
YALDF
1641
YKHGS
1646
LIGLV
1651
QDNRM
1656
NEGDA
1661
YYLLK
1666
DFALT
1671
IKSIS
1676
VSLRE
1681
LCENE
1686
DDNVV
1691
LAFEQ
1696
LSTTF
1701
WEKLN
1706
KV
1711
Mutation Information
DNA mutation:
c.C301A
Peptide Range:
89 ~ 113
Mut AA position:
101 (13 in Wild Type peptide)
Alignment
Wild Type:
"DAEYAYFNFPELLSLRTALILHLQK
||||||||||||.||||||||||||
Mutant:
DAEYAYFNFPELISLRTALILHLQK"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) DDX60
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay