Immunogenicity 15377

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
SYT7 (FPKM: 8)
Transcript ID
ENST00000539008
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (686 aa)
MYRDP
1
EAASP
6
GAPSR
11
DVLLV
16
SAIIT
21
VSLSV
26
TVVLC
31
GLCHW
36
CQRKL
41
GKRYK
46
NSLET
51
VGTPD
56
SGRGR
61
SEKKA
66
INDLD
71
RDFWN
76
NNEST
81
VQQKW
86
SSYPP
91
KEFIL
96
NISPY
101
APYGD
106
PRLSL
111
NGTLL
116
SGAKV
121
AAAAG
126
LAVER
131
EGRLG
136
EKPAP
141
VPPPG
146
EDALR
151
SGGAA
156
PSEPG
161
SGGKA
166
GRGRW
171
RTVQS
176
HLAAG
181
KLNLS
186
NFEDS
191
TLSTA
196
TTLES
201
IPSST
206
GEPKC
211
QRPRT
216
LMRQQ
221
SLQQP
226
LSQHQ
231
RGRQP
236
SQPTT
241
SQSLG
246
QLQAH
251
MASAP
256
GPNPR
261
AYGRG
266
QARQG
271
TSAGS
276
KYRAA
281
GGRSR
286
SNPGS
291
WDHVV
296
GQIRN
301
RGLDM
306
KSFLE
311
GRMVV
316
LSLVL
321
GLSEQ
326
DDFAN
331
IPDLQ
336
NPGTQ
341
QNQNA
346
QGDKR
351
LPAGG
356
KAVNT
361
APVPG
366
QTPHD
371
ESDRR
376
TEPRS
381
SVSDL
386
VNSLT
391
SEMLM
396
LSPGS
401
EEDEA
406
HEGCS
411
RENLG
416
RIQFS
421
VGYNF
426
QESTL
431
TVKIM
436
KAQEL
441
PAKDF
446
SGTSD
451
PFVKI
456
YLLPD
461
KKHKL
466
ETKVK
471
RKNLN
476
PHWNE
481
TFLFE
486
GFPYE
491
KVVQR
496
ILYLQ
501
VLDYD
506
RFSRN
511
DPIGE
516
VSIPL
521
NKVDL
526
TQMQT
531
FWKDL
536
KPCSD
541
GSGSR
546
GELLL
551
SLCYN
556
PSANS
561
IIVNI
566
IKARN
571
LKAMD
576
IGGTS
581
DPYVK
586
VWLMY
591
KDKRV
596
EKKKT
601
VTMKR
606
NLNPI
611
FNESF
616
AFDIP
621
TEKLR
626
ETTII
631
ITVMD
636
KDKLS
641
RNDVI
646
GKIYL
651
SWKSG
656
PGEVK
661
HWKDM
666
IARPR
671
QPVAQ
676
WHQLK
681
A
686
Mutation Information
DNA mutation:
c.A766C
Peptide Range:
244 ~ 268
Mut AA position:
256 (13 in Wild Type peptide)
Alignment
Wild Type:
"TTSQSLGQLQAHMASAPGPNPRAYG
||||||||||||.||||||||||||
Mutant:
TTSQSLGQLQAHLASAPGPNPRAYG"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) SYT7

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay