Immunogenicity 15391

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
ADAMTSL2 (FPKM: 3.4)
Transcript ID
ENST00000354484
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (951 aa)
MDGRW
1
QCSCW
6
AWFLL
11
VLAVV
16
AGDTV
21
STGST
26
DNSPT
31
SNSLE
36
GGTDA
41
TAFWW
46
GEWTK
51
WTACS
56
RSCGG
61
GVTSQ
66
ERHCL
71
QQRRK
76
SVPGP
81
GNRTC
86
TGTSK
91
RYQLC
96
RVQEC
101
PPDGR
106
SFREE
111
QCVSF
116
NSHVY
121
NGRTH
126
QWKPL
131
YPDDY
136
VHISS
141
KPCDL
146
HCTTV
151
DGQRQ
156
LMVPA
161
RDGTS
166
CKLTD
171
LRGVC
176
VSGKC
181
EPIGC
186
DGVLF
191
STHTL
196
DKCGI
201
CQGDG
206
SSCTH
211
VTGNY
216
RKGNA
221
HLGYS
226
LVTHI
231
PAGAR
236
DIQIV
241
ERKKS
246
ADVLA
251
LADEA
256
GYYFF
261
NGNYK
266
VDSPK
271
NFNIA
276
GTVVK
281
YRRPM
286
DVYET
291
GIEYI
296
VAQGP
301
TNQGL
306
NVMVW
311
NQNGK
316
SPSIT
321
FEYTL
326
LQPPH
331
ESRPQ
336
PIYYG
341
FSESA
346
ESQGL
351
DGAGL
356
MGFVP
361
HNGSL
366
YGQAS
371
SERLG
376
LDNRL
381
FGHPG
386
LDMEL
391
GPSQG
396
QETNE
401
VCEQA
406
GGGAC
411
EGPPR
416
GKGFR
421
DRNVT
426
GTPLT
431
GDKDD
436
EEVDT
441
HFASQ
446
EFFSA
451
NAISD
456
QLLGA
461
GSDLK
466
DFTLN
471
ETVNS
476
IFAQG
481
APRSS
486
LAESF
491
FVDYE
496
ENEGA
501
GPYLL
506
NGSYL
511
ELSSD
516
RVANS
521
SSEAP
526
FPNVS
531
TSLLT
536
SAGNR
541
THKAR
546
TRPKA
551
RKQGV
556
SPADM
561
YRWKL
566
SSHEP
571
CSATC
576
TTGVM
581
SAYAM
586
CVRYD
591
GVEVD
596
DSYCD
601
ALTRP
606
EPVHE
611
FCAGR
616
ECQPR
621
WETSS
626
WSECS
631
RTCGE
636
GYQFR
641
VVRCW
646
KMLSP
651
GFDSS
656
VYSDL
661
CEAAE
666
AVRPE
671
ERKTC
676
RNPAC
681
GPQWE
686
MSEWS
691
ECTAK
696
CGERS
701
VVTRD
706
IRCSE
711
DEKLC
716
DPNTR
721
PVGEK
726
NCTGP
731
PCDRQ
736
WTVSD
741
WGPCS
746
GSCGQ
751
GRTIR
756
HVYCK
761
TSDGR
766
VVPES
771
QCQME
776
TKPLA
781
IHPCG
786
DKNCP
791
AHWLA
796
QDWER
801
CNTTC
806
GRGVK
811
KRLVL
816
CMELA
821
NGKPQ
826
TRSGP
831
ECGLA
836
KKPPE
841
ESTCF
846
ERPCF
851
KWYTS
856
PWSEC
861
TKTCG
866
VGVRM
871
RDVKC
876
YQGTD
881
IVRGC
886
DPLVK
891
PVGRQ
896
ACDLQ
901
PCPTE
906
PPDDS
911
CQDQP
916
GTNCA
921
LAIKV
926
NLCGH
931
WYYSK
936
ACCRS
941
CRPPH
946
S
951
Mutation Information
DNA mutation:
c.A1258T
Peptide Range:
408 ~ 432
Mut AA position:
420 (13 in Wild Type peptide)
Alignment
Wild Type:
"EQAGGGACEGPPRGKGFRDRNVTGT
||||||||||||.||||||||||||
Mutant:
EQAGGGACEGPPWGKGFRDRNVTGT"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) ADAMTSL2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay