Immunogenicity 15402
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
DUOX2 (FPKM: 6.33)
Transcript ID
ENST00000389039
HLA INFO
C*16:01
TCR INFO
No TCR info found!
Full length protein sequence (1548 aa)
MLRAR
1
PEALM
6
LLGAL
11
LTGSL
16
GPSGS
21
QDALS
26
LPWEV
31
QRYDG
36
WFNNL
41
RHHER
46
GAVGC
51
RLQRR
56
VPANY
61
ADGVY
66
QALEE
71
PQLPN
76
PRRLS
81
NAATR
86
GIAGL
91
PSLHN
96
RTVLG
101
VFFGY
106
HVLSD
111
VVSVE
116
TPGCP
121
AEFLN
126
IRIPP
131
GDPVF
136
DPDQR
141
GDVVL
146
PFQRS
151
RWDPE
156
TGRSP
161
SNPRD
166
LANQV
171
TGWLD
176
GSAIY
181
GSSHS
186
WSDAL
191
RSFSG
196
GQLAS
201
GPDPA
206
FPRDS
211
QNPLL
216
MWAAP
221
DPATG
226
QNGPR
231
GLYAF
236
GAERG
241
NREPF
246
LQALG
251
LLWFR
256
YHNLW
261
AQRLA
266
RQHPD
271
WEDEE
276
LFQHA
281
RKRVI
286
ATYQN
291
IAVYE
296
WLPSF
301
LQKTL
306
PEYTG
311
YRPFL
316
DPSIS
321
PEFVV
326
ASEQF
331
FSTMV
336
PPGVY
341
MRNAS
346
CHFRK
351
VLNKG
356
FQSSQ
361
ALRVC
366
NNYWI
371
RENPN
376
LNSTQ
381
EVNEL
386
LLGMA
391
SQISE
396
LEDNI
401
VVEDL
406
RDYWP
411
GPGKF
416
SRTDY
421
VASSI
426
QRGRD
431
MGLPS
436
YSQAL
441
LAFGL
446
DIPRN
451
WSDLN
456
PNVDP
461
QVLEA
466
TAALY
471
NQDLS
476
QLELL
481
LGGLL
486
ESHGD
491
PGPLF
496
SAIVL
501
DQFVR
506
LRDGD
511
RYWFE
516
NTRNG
521
LFSKK
526
EIEDI
531
RNTTL
536
RDVLV
541
AVINI
546
DPSAL
551
QPNVF
556
VWHKG
561
APCPQ
566
PKQLT
571
TDGLP
576
QCAPL
581
TVLDF
586
FEGSS
591
PGFAI
596
TIIAL
601
CCLPL
606
VSLLL
611
SGVVA
616
YFRGR
621
EHKKL
626
QKKLK
631
ESVKK
636
EAAKD
641
GVPAM
646
EWPGP
651
KERSS
656
PIIIQ
661
LLSDR
666
CLQVL
671
NRHLT
676
VLRVV
681
QLQPL
686
QQVNL
691
ILSNN
696
RGCRT
701
LLLKI
706
PKEYD
711
LVLLF
716
SSEEE
721
RGAFV
726
QQLWD
731
FCVRW
736
ALGLH
741
VAEMS
746
EKELF
751
RKAVT
756
KQQRE
761
RILEI
766
FFRHL
771
FAQVL
776
DINQA
781
DAGTL
786
PLDSS
791
QKVRE
796
ALTCE
801
LSRAE
806
FAESL
811
GLKPQ
816
DMFVE
821
SMFSL
826
ADKDG
831
NGYLS
836
FREFL
841
DILVV
846
FMKGS
851
PEDKS
856
RLMFT
861
MYDLD
866
ENGFL
871
SKDEF
876
FTMMR
881
SFIEI
886
SNNCL
891
SKAQL
896
AEVVE
901
SMFRE
906
SGFQD
911
KEELT
916
WEDFH
921
FMLRD
926
HDSEL
931
RFTQL
936
CVKGG
941
GGGGN
946
GIRDI
951
FKQNI
956
SCRVS
961
FITRT
966
PGERS
971
HPQGL
976
GPPAP
981
EAPEL
986
GGPGL
991
KKRFG
996
KKAAV
1001
PTPRL
1006
YTEAL
1011
QEKMQ
1016
RGFLA
1021
QKLQQ
1026
YKRFV
1031
ENYRR
1036
HIVCV
1041
AIFSA
1046
ICVGV
1051
FADRA
1056
YYYGF
1061
ASPPS
1066
DIAQT
1071
TLVGI
1076
ILSRG
1081
TAASV
1086
SFMFS
1091
YILLT
1096
MCRNL
1101
ITFLR
1106
ETFLN
1111
RYVPF
1116
DAAVD
1121
FHRWI
1126
AMAAV
1131
VLAIL
1136
HSAGH
1141
AVNVY
1146
IFSVS
1151
PLSLL
1156
ACIFP
1161
NVFVN
1166
DGSKL
1171
PQKFY
1176
WWFFQ
1181
TVPGM
1186
TGVLL
1191
LLVLA
1196
IMYVF
1201
ASHHF
1206
RRRSF
1211
RGFWL
1216
THHLY
1221
ILLYA
1226
LLIIH
1231
GSYAL
1236
IQLPT
1241
FHIYF
1246
LVPAI
1251
IYGGD
1256
KLVSL
1261
SRKKV
1266
EISVV
1271
KAELL
1276
PSGVT
1281
YLQFQ
1286
RPQGF
1291
EYKSG
1296
QWVRI
1301
ACLAL
1306
GTTEY
1311
HPFTL
1316
TSAPH
1321
EDTLS
1326
LHIRA
1331
VGPWT
1336
TRLRE
1341
IYSSP
1346
KGNGC
1351
AGYPK
1356
LYLDG
1361
PFGEG
1366
HQEWH
1371
KFEVS
1376
VLVGG
1381
GIGVT
1386
PFASI
1391
LKDLV
1396
FKSSL
1401
GSQML
1406
CKKIY
1411
FIWVT
1416
RTQRQ
1421
FEWLA
1426
DIIQE
1431
VEEND
1436
HQDLV
1441
SVHIY
1446
VTQLA
1451
EKFDL
1456
RTTML
1461
YICER
1466
HFQKV
1471
LNRSL
1476
FTGLR
1481
SITHF
1486
GRPPF
1491
EPFFN
1496
SLQEV
1501
HPQVR
1506
KIGVF
1511
SCGPP
1516
GMTKN
1521
VEKAC
1526
QLVNR
1531
QDRAH
1536
FMHHY
1541
ENF
1546
Mutation Information
DNA mutation:
c.G1587T
Peptide Range:
517 ~ 541
Mut AA position:
529 (13 in Wild Type peptide)
Alignment
Wild Type:
"YWFENTRNGLFSKKEIEDIRNTTLR
||||||||||||.||||||||||||
Mutant:
YWFENTRNGLFSNKEIEDIRNTTLR"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) DUOX2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay