Immunogenicity 15410

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
DNAJB6 (FPKM: 36.06)
Transcript ID
ENST00000262177
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (326 aa)
MVDYY
1
EVLGV
6
QRHAS
11
PEDIK
16
KAYRK
21
LALKW
26
HPDKN
31
PENKE
36
EAERK
41
FKQVA
46
EAYEV
51
LSDAK
56
KRDIY
61
DKYGK
66
EGLNG
71
GGGGG
76
SHFDS
81
PFEFG
86
FTFRN
91
PDDVF
96
REFFG
101
GRDPF
106
SFDFF
111
EDPFE
116
DFFGN
121
RRGPR
126
GSRSR
131
GTGSF
136
FSAFS
141
GFPSF
146
GSGFS
151
SFDTG
156
FTSFG
161
SLGHG
166
GLTSF
171
SSTSF
176
GGSGM
181
GNFKS
186
ISTST
191
KMVNG
196
RKITT
201
KRIVE
206
NGQER
211
VEVEE
216
DGQLK
221
SLTIN
226
GVADD
231
DALAE
236
ERMRR
241
GQNAL
246
PAQPA
251
GLRPP
256
KPPRP
261
ASLLR
266
HAPHC
271
LSEEE
276
GEQDR
281
PRAPG
286
PWDPL
291
ASAAG
296
LKEGG
301
KRKKQ
306
KQREE
311
SKKKK
316
STKGN
321
H
326
Mutation Information
DNA mutation:
c.A743C
Peptide Range:
236 ~ 260
Mut AA position:
248 (13 in Wild Type peptide)
Alignment
Wild Type:
"DALAEERMRRGQNALPAQPAGLRPP
||||||||||||.||||||||||||
Mutant:
DALAEERMRRGQTALPAQPAGLRPP"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) DNAJB6

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay