Immunogenicity 15425

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
DPY19L2 (FPKM: 0.11)
Transcript ID
ENST00000324472
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (758 aa)
MRKQG
1
VSSKR
6
LQSSG
11
RSQSK
16
GRRGA
21
SLARE
26
PEVEE
31
EMEKS
36
ALGGG
41
KLPRG
46
SWRSS
51
PGRIQ
56
SLKER
61
KGLEL
66
EVVAK
71
TFLLG
76
PFQFV
81
RNSLA
86
QLREK
91
VQELQ
96
ARRFS
101
SRTTL
106
GIAVF
111
VAILH
116
WLHLV
121
TLFEN
126
DRHFS
131
HLSSL
136
EREMT
141
FRTEM
146
GLYYS
151
YFKTI
156
IEAPS
161
FLEGL
166
WMIMN
171
DRLTE
176
YPLII
181
NAIKR
186
FHLYP
191
EVIIA
196
SWYCT
201
FMGIM
206
NLFGL
211
ETKTC
216
WNVTR
221
IEPLN
226
EVQSC
231
EGLGD
236
PACFY
241
VGVIF
246
ILNGL
251
MMGLF
256
FMYGA
261
YLSGT
266
QLGGL
271
ITVLC
276
FFFNH
281
GEATR
286
VMWTP
291
PLRES
296
FSYPF
301
LVLQM
306
CILTL
311
ILRTS
316
SNDRR
321
PFIAL
326
CLSNV
331
AFMLP
336
WQFAQ
341
FILFT
346
QIASL
351
FPMYV
356
VGYIE
361
PSKFQ
366
KIIYM
371
NMISV
376
TLSFI
381
LMFGN
386
SMYLS
391
SYYSS
396
SLLMT
401
WAIIL
406
KRNEI
411
QKLGV
416
SKLNF
421
WLIQG
426
SAWWC
431
GTIIL
436
KFLTS
441
KILGV
446
SDHIR
451
LSDLI
456
AARIL
461
RYTDF
466
DTLIY
471
TCAPE
476
FDFME
481
KATPL
486
RYTKT
491
LLLPV
496
VMVIT
501
CFIFK
506
KTVRD
511
ISYVL
516
ATNIY
521
LRKQL
526
LEHSE
531
LAFHT
536
LQLLV
541
FTALA
546
ILIMR
551
LKMFL
556
TPHMC
561
VMASL
566
ICSRQ
571
LFGWL
576
FRRVR
581
FEKVI
586
FGILT
591
VMSIQ
596
GYANL
601
RNQWS
606
IIGEF
611
NNLPQ
616
EELLQ
621
WIKYS
626
TTSDA
631
VFAGA
636
MPTMA
641
SIKLS
646
TLHPI
651
VNHPH
656
YEDAD
661
LRART
666
KIVYS
671
TYSRK
676
SAKEV
681
RDKLL
686
ELHVN
691
YYVLE
696
EAWCV
701
VRTKP
706
GCSML
711
EIWDV
716
EDPSN
721
AANPP
726
LCSVL
731
LEDAR
736
PYFTT
741
VFQNS
746
VYRVL
751
KVN
756
Mutation Information
DNA mutation:
c.T1792C
Peptide Range:
586 ~ 610
Mut AA position:
598 (13 in Wild Type peptide)
Alignment
Wild Type:
"FEKVIFGILTVMSIQGYANLRNQWS
||||||||||||.||||||||||||
Mutant:
FEKVIFGILTVMPIQGYANLRNQWS"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) DPY19L2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay