Immunogenicity 15431

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
LINC00115 (FPKM: 1.4)
Transcript ID
uc010nxx.2
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (163 aa)
MWLVF
1
HRPHP
6
RPSWP
11
LRAAL
16
GFGRR
21
QSSLR
26
CFPVL
31
PSARP
36
YVSAN
41
PTLRG
46
GRLRQ
51
DPESE
56
TGVGD
61
LPDPV
66
TTLVL
71
LHNRL
76
PLAVT
81
VGCLP
86
SRCPT
91
EKRAP
96
PWQGL
101
LHCLA
106
VDVEV
111
GQESE
116
EKTER
121
REVEP
126
TSEKR
131
GGKFR
136
WEVDG
141
SEEFE
146
QTPTV
151
KESDL
156
SKQ
161
Mutation Information
DNA mutation:
c.T47A
Peptide Range:
4 ~ 28
Mut AA position:
16 (13 in Wild Type peptide)
Alignment
Wild Type:
"VFHRPHPRPSWPLRAALGFGRRQSS
||||||||||||.||||||||||||
Mutant:
VFHRPHPRPSWPHRAALGFGRRQSS"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) LINC00115

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay