Immunogenicity 15439

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PPM1K (FPKM: 3.24)
Transcript ID
uc010ikp.2
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (233 aa)
MSTAA
1
LITLV
6
RSGGN
11
QVRRR
16
VLLSS
21
RLLQD
26
DRRVT
31
PTCHS
36
STSEP
41
RCSRF
46
DPDGS
51
GSPAT
56
WDNFG
61
IWDNR
66
IDEPI
71
LLPPS
76
IKYGK
81
PIPKI
86
SLENV
91
GCASQ
96
IGKRK
101
ENEDR
106
FDFAQ
111
LTDEV
116
LYFAV
121
YDGHG
126
GPAAA
131
DFCHT
136
HMEKC
141
IMDLL
146
PKEKN
151
LETLL
156
TLAFL
161
EIDKA
166
FSSHA
171
RLSAD
176
ENCAW
181
SAALD
186
LEPVD
191
TICGA
196
SVERE
201
ICLIL
206
SQVKE
211
SSGSY
216
PGLRE
221
GSHIS
226
LSH
231
Mutation Information
DNA mutation:
c.G580A
Peptide Range:
182 ~ 206
Mut AA position:
194 (13 in Wild Type peptide)
Alignment
Wild Type:
"NCAWSAALDLEPVDTICGASVEREI
||||||||||||.||||||||||||
Mutant:
NCAWSAALDLEPMDTICGASVEREI"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) PPM1K

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay