Immunogenicity 15450
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
TMEM132D (FPKM: 0.01)
Transcript ID
NM_133448
HLA INFO
C*16:01
TCR INFO
No TCR info found!
Full length protein sequence (1099 aa)
MCPSE
1
MGTLW
6
HHWSP
11
VLISL
16
AALFS
21
KVTEG
26
RGILE
31
SIQRF
36
SLLPT
41
YLPVT
46
YHINN
51
ADVSF
56
FLKEA
61
NQDIM
66
RNSSL
71
QSRVE
76
SFLIY
81
KSRRL
86
PVLNA
91
SYGPF
96
SIEQV
101
VPQDL
106
MLPSN
111
PFGFT
116
NKFSL
121
NWKLK
126
AHILR
131
DKVYL
136
SRPKV
141
QVLFH
146
IMGRD
151
WDDRS
156
AGEKL
161
PCLRV
166
FAFRE
171
TREVR
176
GSCRL
181
QGDLG
186
LCVAE
191
LELLS
196
SWFSP
201
PTVVA
206
GRRKS
211
VDQPE
216
GTPVE
221
LYYTV
226
HPGGE
231
RGDCV
236
REDAR
241
RSNGI
246
RTGHS
251
DIDES
256
GPPLQ
261
RIGSI
266
FLYQT
271
HRKPS
276
LRELR
281
LDNSV
286
AIHYI
291
PKTVR
296
KGDVL
301
TFPVS
306
ISRNS
311
TEDRF
316
TLRAK
321
VKKGV
326
NIIGV
331
RASSP
336
SIWDV
341
KERTD
346
YTGKY
351
APAVI
356
VCQKK
361
AAGSE
366
NSADG
371
ASYEV
376
MQIDV
381
EVEEP
386
GDLPA
391
TQLVT
396
WQVEY
401
PGEIT
406
SDLGV
411
SKIYV
416
SPKDL
421
IGVVP
426
LAMEA
431
EILNT
436
AILTG
441
KTVAV
446
PVKVV
451
SVEDD
456
GTVTE
461
LLESV
466
ECRSS
471
DEDVI
476
KVSDR
481
CDYVF
486
VNGKE
491
MKGKV
496
NVVVN
501
FTYQH
506
LSSPL
511
EMTVW
516
VPRLP
521
LQIEV
526
SDTEL
531
NQIKG
536
WRVPI
541
VSSRR
546
PAGDS
551
EEEED
556
DERRG
561
RGCTL
566
QYQHA
571
MVRVL
576
TQFVA
581
EAAGP
586
GGHLA
591
HLLGS
596
DWQVD
601
ITELI
606
NDFMQ
611
VEEPR
616
IAKLQ
621
GGQIL
626
MGQEL
631
GMTTI
636
QILSP
641
LSDTI
646
LAEKT
651
ITVLD
656
EKVTI
661
TDLGV
666
QLVTG
671
LSLSL
676
QLSPG
681
SNRAI
686
FATAV
691
AQELL
696
QRPKQ
701
EAAIS
706
CWVQF
711
SDGSV
716
TPLDI
721
YDGKD
726
FSLMA
731
TSLDE
736
KVVSI
741
HQDPK
746
FKWPI
751
IAAET
756
EGQGT
761
LVKVE
766
MVISE
771
SCQKS
776
KRKSV
781
LAVGT
786
ANIKV
791
KFGQN
796
DANPN
801
TSDSR
806
HTGAG
811
VHMEN
816
NVSDR
821
RPKKP
826
SQEWG
831
SQEGQ
836
YYGSS
841
SMGLM
846
EGRGT
851
TTDRS
856
ILQKK
861
KGQES
866
LLDDN
871
SHLQT
876
IPSDL
881
TSFPA
886
QVDLP
891
RSNGE
896
MDGND
901
LMQAS
906
KGLSD
911
LEIGM
916
YALLG
921
VFCLA
926
ILVFL
931
INCVT
936
FALKY
941
RHKQV
946
PFEEQ
951
EGMSH
956
SHDWV
961
GLSNR
966
TELLE
971
NHINF
976
ASSQD
981
EQITA
986
IDRGM
991
DFEES
996
KYLLS
1001
TNSQK
1006
SINGQ
1011
LFKPL
1016
GPIII
1021
DGKDQ
1026
KSEPP
1031
TSPTS
1036
KRKRV
1041
KFTTF
1046
TAVSS
1051
DDEYP
1056
TRNSI
1061
VMSSE
1066
DDIKW
1071
VCQDL
1076
DPGDC
1081
KELHN
1086
YMERL
1091
HENV
1096
Mutation Information
DNA mutation:
c.C2567T
Peptide Range:
844 ~ 868
Mut AA position:
856 (13 in Wild Type peptide)
Alignment
Wild Type:
"SSSMGLMEGRGTTTDRSILQKKKGQ
||||||||||||.||||||||||||
Mutant:
SSSMGLMEGRGTMTDRSILQKKKGQ"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) TMEM132D
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay