Immunogenicity 15476

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
KDM2A (FPKM: 20.88)
Transcript ID
NM_001256405
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (723 aa)
MCSGR
1
FQNIQ
6
VNPDF
11
PRGRI
16
SNSFR
21
RTSST
26
ENKTK
31
TLGKL
36
HQEPR
41
QLQSD
46
GKRKI
51
LLEEL
56
ANSDP
61
KLALT
66
GVPIV
71
QWPKR
76
DKLKF
81
PTRPK
86
VRVPT
91
IPITK
96
PHTMK
101
PAPRL
106
TPVRP
111
AAASP
116
IVSGA
121
RRRRV
126
RCRKC
131
KACVQ
136
GECGV
141
CHYCR
146
DMKKF
151
GGPGR
156
MKQSC
161
VLRQC
166
LAPRL
171
PHSVT
176
CSLCG
181
EVDQN
186
EETQD
191
FEKKL
196
MECCI
201
CNEIV
206
HPGCL
211
QMDGE
216
GLLNE
221
ELPNC
226
WECPK
231
CYQED
236
SSEKA
241
QKRKM
246
EESDE
251
EAVQA
256
KVLRP
261
LRSCD
266
EPLTP
271
PPHSP
276
TSMLQ
281
LIHDP
286
VSPRG
291
MVTRS
296
SPGAG
301
PSDHH
306
SASRD
311
ERFKR
316
RQLLR
321
LQATE
326
RTMVR
331
EKENN
336
PSGKK
341
ELSEV
346
EKAKI
351
RGSYL
356
TVTLQ
361
RPTKE
366
LHGTS
371
IVPKL
376
QAITA
381
SSANL
386
RHSPR
391
VLVQH
396
CPART
401
PQRGD
406
EEGLG
411
GEEEE
416
EEEEE
421
EEDDS
426
AEEGG
431
AARLN
436
GRGSW
441
AQDGD
446
ESWMQ
451
REVWM
456
SVFRY
461
LSRRE
466
LCECM
471
RVCKT
476
WYKWC
481
CDKRL
486
WTKID
491
LSRCK
496
AIVPQ
501
ALSGI
506
IKRQP
511
VSLDL
516
SWTNI
521
SKKQL
526
TWLVN
531
RLPGL
536
KDLLL
541
AGCSW
546
SAVSA
551
LSTSS
556
CPLLR
561
TLDLR
566
WAVGI
571
KDPQI
576
RDLLT
581
PPADK
586
PGQDN
591
RSKLR
596
NMTDF
601
RLAGL
606
DITDA
611
TLRLI
616
IRHMP
621
LLSRL
626
DLSHC
631
SHLTD
636
QSSNL
641
LTAVG
646
SSTRY
651
SLTEL
656
NMAGC
661
NKLTD
666
QTLIY
671
LRRIA
676
NVTLI
681
DLRGC
686
KQITR
691
KACEH
696
FISDL
701
SINSL
706
YCLSD
711
EKLIQ
716
KIS
721
Mutation Information
DNA mutation:
c.G202T
Peptide Range:
56 ~ 80
Mut AA position:
68 (13 in Wild Type peptide)
Alignment
Wild Type:
"LLEELANSDPKLALTGVPIVQWPKR
||||||||||||.||||||||||||
Mutant:
LLEELANSDPKLSLTGVPIVQWPKR"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) KDM2A

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay