Immunogenicity 1548

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LRFN5
Transcript ID
ENST00000298119
HLA INFO
B*08:01
TCR INFO

No TCR info found!

T cell Tumor cell B*08:01
sequence
Full length protein sequence (719 aa)
MEKIL
1
FYLFL
6
IGIAV
11
KAQIC
16
PKRCV
21
CQILS
26
PNLAT
31
LCAKK
36
GLLFV
41
PPNID
46
RRTVE
51
LRLAD
56
NFVTN
61
IKRKD
66
FANMT
71
SLVDL
76
TLSRN
81
TISFI
86
TPHAF
91
ADLRN
96
LRALH
101
LNSNR
106
LTKIT
111
NDMFS
116
GLSNL
121
HHLIL
126
NNNQL
131
TLISS
136
TAFDD
141
VFALE
146
ELDLS
151
YNNLE
156
TIPWD
161
AVEKM
166
VSLHT
171
LSLDH
176
NMIDN
181
IPKGT
186
FSHLH
191
KMTRL
196
DVTSN
201
KLQKL
206
PPDPL
211
FQRAQ
216
VLATS
221
GIISP
226
STFAL
231
SFGGN
236
PLHCN
241
CELLW
246
LRRLS
251
REDDL
256
ETCAS
261
PPLLT
266
GRYFW
271
SIPEE
276
EFLCE
281
PPLIT
286
RHTHE
291
MRVLE
296
GQRAT
301
LRCKA
306
RGDPE
311
PAIHW
316
ISPEG
321
KLISN
326
ATRSL
331
VYDNG
336
TLDIL
341
ITTVK
346
DTGAF
351
TCIAS
356
NPAGE
361
ATQIV
366
DLHII
371
KLPHL
376
LNSTN
381
HIHEP
386
DPGSS
391
DISTS
396
TKSGS
401
NTSSS
406
NGDTK
411
LSQDK
416
IVVAE
421
ATSST
426
ALLKF
431
NFQRN
436
IPGIR
441
MFQIQ
446
YNGTY
451
DDTLV
456
YRMIP
461
PTSKT
466
FLVNN
471
LAAGT
476
MYDLC
481
VLAIY
486
DDGIT
491
SLTAT
496
RVVGC
501
IQFTT
506
EQDYV
511
RCHFM
516
QSQFL
521
GGTMI
526
IIIGG
531
IIVAS
536
VLVFI
541
IILMI
546
RYKVC
551
NNNGQ
556
HKVTK
561
VSNVY
566
SQTNG
571
AQIQG
576
CSVTL
581
PQSVS
586
KQAVG
591
HEENA
596
QCCKA
601
TSDNV
606
IQSSE
611
TCSSQ
616
DSSTT
621
TSALP
626
PSWTS
631
STSVS
636
QKQKR
641
KTGTK
646
PSTEP
651
QNEAV
656
TNVES
661
QNTNR
666
NNSTA
671
LQLAS
676
RPPDS
681
VTEGP
686
TSKRA
691
HIKPN
696
ALLTN
701
VDQIV
706
QETQR
711
LELI
716
Mutation Information
DNA mutation:
None
Peptide Range:
207 ~ 231
Mut AA position:
219 (13 in Wild Type peptide)
Alignment
Wild Type:
"LQKLPPDPLFQRAQVLATSGIISPS
||||||||||||.||||||||||||
Mutant:
LQKLPPDPLFQRTQVLATSGIISPS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LRFN5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay