Immunogenicity 15482
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PCSK5 (FPKM: 1.82)
Transcript ID
NM_001190482
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (1860 aa)
MGWGS
1
RCCCP
6
GRLDL
11
LCVLA
16
LLGGC
21
LLPVC
26
RTRVY
31
TNHWA
36
VKIAG
41
GFPEA
46
NRIAS
51
KYGFI
56
NIGQI
61
GALKD
66
YYHFY
71
HSRTI
76
KRSVI
81
SSRGT
86
HSFIS
91
MEPKV
96
EWIQQ
101
QVVKK
106
RTKRD
111
YDFSR
116
AQSTY
121
FNDPK
126
WPSMW
131
YMHCS
136
DNTHP
141
CQSDM
146
NIEGA
151
WKRGY
156
TGKNI
161
VVTIL
166
DDGIE
171
RTHPD
176
LMQNY
181
DALAS
186
CDVNG
191
NDLDP
196
MPRYD
201
ASNEN
206
KHGTR
211
CAGEV
216
AAAAN
221
NSHCT
226
VGIAF
231
NAKIG
236
GVRML
241
DGDVT
246
DMVEA
251
KSVSF
256
NPQHV
261
HIYSA
266
SWGPD
271
DDGKT
276
VDGPA
281
PLTRQ
286
AFENG
291
VRMGR
296
RGLGS
301
VFVWA
306
SGNGG
311
RSKDH
316
CSCDG
321
YTNSI
326
YTISI
331
SSTAE
336
SGKKP
341
WYLEE
346
CSSTL
351
ATTYS
356
SGESY
361
DKKII
366
TTDLR
371
QRCTD
376
NHTGT
381
SASAP
386
MAAGI
391
IALAL
396
EANPF
401
LTWRD
406
VQHVI
411
VRTSR
416
AGHLN
421
ANDWK
426
TNAAG
431
FKVSH
436
LYGFG
441
LMDAE
446
AMVME
451
AEKWT
456
TVPRQ
461
HVCVE
466
STDRQ
471
IKTIR
476
PNSAV
481
RSIYK
486
ASGCS
491
DNPNR
496
HVNYL
501
EHVVV
506
RITIT
511
HPRRG
516
DLAIY
521
LTSPS
526
GTRSQ
531
LLANR
536
LFDHS
541
MEGFK
546
NWEFM
551
TIHCW
556
GERAA
561
GDWVL
566
EVYDT
571
PSQLR
576
NFKTP
581
GKLKE
586
WSLVL
591
YGTSV
596
QPYSP
601
TNEFP
606
KVERF
611
RYSRV
616
EDPTD
621
DYGTE
626
DYAGP
631
CDPEC
636
SEVGC
641
DGPGP
646
DHCND
651
CLHYY
656
YKLKN
661
NTRIC
666
VSSCP
671
PGHYH
676
ADKKR
681
CRKCA
686
PNCES
691
CFGSH
696
GDQCM
701
SCKYG
706
YFLNE
711
ETNSC
716
VTHCP
721
DGSYQ
726
DTKKN
731
LCRKC
736
SENCK
741
TCTEF
746
HNCTE
751
CRDGL
756
SLQGS
761
RCSVS
766
CEDGR
771
YFNGQ
776
DCQPC
781
HRFCA
786
TCAGA
791
GADGC
796
INCTE
801
GYFME
806
DGRCV
811
QSCSI
816
SYYFD
821
HSSEN
826
GYKSC
831
KKCDI
836
SCLTC
841
NGPGF
846
KNCTS
851
CPSGY
856
LLDLG
861
MCQMG
866
AICKD
871
GEYVD
876
EHGHC
881
QTCEA
886
SCAKC
891
QGPTQ
896
EDCTT
901
CPMTR
906
IFDDG
911
RCVSN
916
CPSWK
921
FEFEN
926
QCHPC
931
HHTCQ
936
RCQGS
941
GPTHC
946
TSCGA
951
DNYGR
956
EHFLY
961
QGECG
966
DSCPE
971
GHYAT
976
EGNTC
981
LPCPD
986
NCELC
991
HSVHV
996
CTRCM
1001
KGYFI
1006
APTNH
1011
TCQKL
1016
ECGQG
1021
EVQDP
1026
DYEEC
1031
VPCEE
1036
GCLGC
1041
SLDDP
1046
GTCTS
1051
CAMGY
1056
YRFDH
1061
HCYKT
1066
CPEKT
1071
YSEEV
1076
ECKAC
1081
DSNCG
1086
SCDQN
1091
GCYWC
1096
EEGFF
1101
LLGGS
1106
CVRKC
1111
GPGFY
1116
GDQEM
1121
GECES
1126
CHRAC
1131
ETCTG
1136
PGHDE
1141
CSSCQ
1146
EGLQL
1151
LRGMC
1156
VHATK
1161
TQEEG
1166
KFWND
1171
ILRKL
1176
QPCHS
1181
SCKTC
1186
NGSAT
1191
LCTSC
1196
PKGAY
1201
LLAQA
1206
CVSSC
1211
PQGTW
1216
PSVRS
1221
GSCEN
1226
CTEAC
1231
AICSG
1236
ADLCK
1241
KCQMQ
1246
PGHPL
1251
FLHEG
1256
RCYSK
1261
CPEGS
1266
YAEDG
1271
ICERC
1276
SSPCR
1281
TCEGN
1286
ATNCH
1291
SCEGG
1296
HVLHH
1301
GVCQE
1306
NCPER
1311
HVAVK
1316
GVCKH
1321
CPEMC
1326
QDCIH
1331
EKTCK
1336
ECTPE
1341
FFLHD
1346
DMCHQ
1351
SCPRG
1356
FYADS
1361
RHCVP
1366
CHKDC
1371
LECSG
1376
PKADD
1381
CELCL
1386
ESSWV
1391
LYDGL
1396
CLEEC
1401
PAGTY
1406
YEKET
1411
KECRD
1416
CHKSC
1421
LTCSS
1426
SGTCT
1431
TCQKG
1436
LIMNP
1441
RGSCM
1446
ANEKC
1451
SPSEY
1456
WDEDA
1461
PGCKP
1466
CHVKC
1471
FHCMG
1476
PAEDQ
1481
CQTCP
1486
MNSLL
1491
LNTTC
1496
VKDCP
1501
EGYYA
1506
DEDSN
1511
RCAHC
1516
HSSCR
1521
TCEGR
1526
HSRQC
1531
HSCRP
1536
GWFQL
1541
GKECL
1546
LQCRE
1551
GYYAD
1556
NSTGR
1561
CERCN
1566
RSCKG
1571
CQGPR
1576
PTDCL
1581
SCDRF
1586
FFLLR
1591
SKGEC
1596
HRSCP
1601
DHYYV
1606
EQSTQ
1611
TCERC
1616
HPTCD
1621
QCKGK
1626
GALNC
1631
LSCVW
1636
SYHLM
1641
GGICT
1646
SDCLV
1651
GEYRV
1656
GEGEK
1661
FNCEK
1666
CHESC
1671
MECKG
1676
PGAKN
1681
CTLCP
1686
ANLVL
1691
HMDDS
1696
HCLHC
1701
CNTSD
1706
PPSAQ
1711
ECCDC
1716
QDTTD
1721
ECILR
1726
TSKVR
1731
PATEH
1736
FKTAL
1741
FITSS
1746
MMLVL
1751
LLGAA
1756
VVVWK
1761
KSRGR
1766
VQPAA
1771
KAGYE
1776
KLADP
1781
NKSYS
1786
SYKSS
1791
YREST
1796
SFEED
1801
QVIEY
1806
RDRDY
1811
DEDDD
1816
DDIVY
1821
MGQDG
1826
TVYRK
1831
FKYGL
1836
LDDDD
1841
IDELE
1846
YDDES
1851
YSYYQ
1856
Mutation Information
DNA mutation:
c.G4805A
Peptide Range:
1590 ~ 1614
Mut AA position:
1602 (13 in Wild Type peptide)
Alignment
Wild Type:
"FFFLLRSKGECHRSCPDHYYVEQST
||||||||||||.||||||||||||
Mutant:
FFFLLRSKGECHHSCPDHYYVEQST"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) PCSK5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay