Immunogenicity 15507

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PGBD1 (FPKM: 0.84)
Transcript ID
NM_001184743
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (809 aa)
MYEAL
1
PGPAP
6
ENEDG
11
LVKVK
16
EEDPT
21
WEQVC
26
NSQEG
31
SSHTQ
36
EICRL
41
RFRHF
46
CYQEA
51
HGPQE
56
ALAQL
61
RELCH
66
QWLRP
71
EMHTK
76
EQIME
81
LLVLE
86
QFLTI
91
LPKEL
96
QPCVK
101
TYPLE
106
SGEEA
111
VTVLE
116
NLETG
121
SGDTG
126
QQASV
131
YIQGQ
136
DMHPM
141
VAEYQ
146
GVSLE
151
CQSLQ
156
LLPGI
161
TTLKC
166
EPPQR
171
PQGNP
176
QEVSG
181
PVPHG
186
SAHLQ
191
EKNPR
196
DKAVV
201
PVFNP
206
VRSQT
211
LVKTE
216
EETAQ
221
AVAAE
226
KWSHL
231
SLTRR
236
NLCGN
241
SAQET
246
VMSLS
251
PMTEE
256
IVTKD
261
RLFKA
266
KQETS
271
EEMEQ
276
SGEAS
281
GKPNR
286
ECAPQ
291
IPCST
296
PIATE
301
RTVAH
306
LNTLK
311
DRHPG
316
DLWAR
321
MHISS
326
LEYAA
331
GDITR
336
KGRKK
341
DKARV
346
SELLQ
351
GLSFS
356
GDSDV
361
EKDNE
366
PEIQP
371
AQKKL
376
KVSCF
381
PEKSW
386
TKRDI
391
KPNFP
396
SWSAL
401
DSGLL
406
NLKSE
411
KLNPV
416
ELFEL
421
FFDDE
426
TFNLI
431
VNETN
436
NYASQ
441
KNVSL
446
EVTVQ
451
EMRCV
456
FGVLL
461
LSGFM
466
RHPRR
471
EMYWE
476
VSDTD
481
QNLVR
486
DAIRR
491
DRFEL
496
IFSNL
501
HFADN
506
GHLDQ
511
KDKFT
516
KLRPL
521
IKQMN
526
KNFLL
531
YAPLE
536
EYYCF
541
DKSMC
546
ECFDS
551
DQFLN
556
GKPIR
561
IGYKI
566
WCGTT
571
TQGYL
576
VWFEP
581
YQEES
586
TMKVD
591
EDPDL
596
GLGGN
601
LVMNF
606
ADVLL
611
ERGQY
616
PYHLC
621
FDSFF
626
TSVKL
631
LSALK
636
KKGVR
641
ATGTI
646
RENRT
651
EKCPL
656
MNVEH
661
MKKMK
666
RGYFD
671
FRIEE
676
NNEII
681
LCRWY
686
GDGII
691
SLCSN
696
AVGIE
701
PVNEV
706
SCCDA
711
DNEEI
716
PQISQ
721
PSIVK
726
VYDEC
731
KEGVA
736
KMDQI
741
ISKYR
746
VRIRS
751
KKWYS
756
ILVSY
761
MIDVA
766
MNNAW
771
QLHRA
776
CNPGA
781
SLDPL
786
DFRRF
791
VAHFY
796
LEHNA
801
HLSD
806
Mutation Information
DNA mutation:
c.G1966A
Peptide Range:
644 ~ 668
Mut AA position:
656 (13 in Wild Type peptide)
Alignment
Wild Type:
"VRATGTIRENRTEKCPLMNVEHMKK
||||||||||||.||||||||||||
Mutant:
VRATGTIRENRTKKCPLMNVEHMKK"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) PGBD1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay