Immunogenicity 15511

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
LIX1L (FPKM: 3.1)
Transcript ID
NM_153713
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (337 aa)
METMR
1
AQRLQ
6
PGVGT
11
SGRGT
16
LRALR
21
PGVTG
26
AAAAT
31
ATPPA
36
GPPPA
41
PPPPA
46
PPPPP
51
LLLSG
56
APGLP
61
LPPGA
66
AGSPA
71
VLREA
76
VEAVV
81
RSFAK
86
HTQGY
91
GRVNV
96
VEALQ
101
EFWQM
106
KQSRG
111
ADLKN
116
GALVV
121
YEMVP
126
SNSPP
131
YVCYV
136
TLPGG
141
SCFGS
146
FQFCP
151
TKAEA
156
RRSAA
161
KIALM
166
NSVFN
171
EHPSR
176
RITDE
181
FIEKS
186
VSEAL
191
ASFNG
196
NREEA
201
DNPNT
206
GIGAF
211
RFMLE
216
SNKGK
221
SMLEF
226
QELMT
231
VFQLL
236
HWNGS
241
LKAMR
246
ERQCS
251
RQEVL
256
AHYSH
261
RALDD
266
DIRHQ
271
MALDW
276
VSREQ
281
SVPGA
286
LSREL
291
ASTER
296
ELDEA
301
RLAGK
306
ELRFH
311
KEKKD
316
ILVLA
321
AGQLG
326
NMHSS
331
NC
336
Mutation Information
DNA mutation:
c.G361T
Peptide Range:
109 ~ 133
Mut AA position:
121 (13 in Wild Type peptide)
Alignment
Wild Type:
"QMKQSRGADLKNGALVVYEMVPSNS
||||||||||||.||||||||||||
Mutant:
QMKQSRGADLKNWALVVYEMVPSNS"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) LIX1L

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay