Immunogenicity 15534

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
KCNN3 (FPKM: 0.99)
Transcript ID
NM_001204087
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (746 aa)
MDTSG
1
HFHDS
6
GVGDL
11
DEDPK
16
CPCPS
21
SGDEQ
26
QQQQQ
31
QQQQQ
36
QPPPP
41
APPAA
46
PQQPL
51
GPSLQ
56
PQPPQ
61
LQQQQ
66
QQQQQ
71
QQQQQ
76
PPHPL
81
SQLAQ
86
LQSQP
91
VHPGL
96
LHSSP
101
TAFRA
106
PPSSN
111
STAIL
116
HPSSR
121
QGSQL
126
NLNDH
131
LLGHS
136
PSSTA
141
TSGPG
146
GGSRH
151
RQASP
156
LVHRR
161
DSNPF
166
TEIAM
171
SSCKY
176
SGGVM
181
KPLSR
186
LSASR
191
RNLIE
196
AETEG
201
QPLQL
206
FSPSN
211
PPEIV
216
ISSRE
221
DNHAH
226
QTLLH
231
HPNAT
236
HNHQH
241
AGTTA
246
SSTTF
251
PKANK
256
RKNQN
261
IGYKL
266
GHRRA
271
LFEKR
276
KRLSD
281
YALIF
286
GMFGI
291
VVMVI
296
ETELS
301
WGLYS
306
KDSMF
311
SLALK
316
CLISL
321
STIIL
326
LGLII
331
AYHTR
336
EVQLF
341
VIDNG
346
ADDWR
351
IAMTY
356
ERILY
361
ISLEM
366
LVCAI
371
HPIPG
376
EYKFF
381
WTARL
386
AFSYT
391
PSRAE
396
ADVDI
401
ILSIP
406
MFLRL
411
YLIAR
416
VMLLH
421
SKLFT
426
DASSR
431
SIGAL
436
NKINF
441
NTRFV
446
MKTLM
451
TICPG
456
TVLLV
461
FSISL
466
WIIAA
471
WTVRV
476
CESPE
481
SPAQP
486
SGSSL
491
PAWYH
496
DQQDV
501
TSNFL
506
GAMWL
511
ISITF
516
LSIGY
521
GDMVP
526
HTYCG
531
KGVCL
536
LTGIM
541
GAGCT
546
ALVVA
551
VVARK
556
LELTK
561
AEKHV
566
HNFMM
571
DTQLT
576
KRIKN
581
AAANV
586
LRETW
591
LIYKH
596
TKLLK
601
KIDHA
606
KVRKH
611
QRKFL
616
QAIHQ
621
LRSVK
626
MEQRK
631
LSDQA
636
NTLVD
641
LSKMQ
646
NVMYD
651
LITEL
656
NDRSE
661
DLEKQ
666
IGSLE
671
SKLEH
676
LTASF
681
NSLPL
686
LIADT
691
LRQQQ
696
QQLLS
701
AIIEA
706
RGVSV
711
AVGTT
716
HTPIS
721
DSPIG
726
VSSTS
731
FPTPY
736
TSSSS
741
C
746
Mutation Information
DNA mutation:
c.G2176T
Peptide Range:
714 ~ 738
Mut AA position:
726 (13 in Wild Type peptide)
Alignment
Wild Type:
"SVAVGTTHTPISDSPIGVSSTSFPT
||||||||||||.||||||||||||
Mutant:
SVAVGTTHTPISYSPIGVSSTSFPT"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) KCNN3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay