Immunogenicity 15539

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
LMOD1 (FPKM: 5.83)
Transcript ID
NM_012134
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (600 aa)
MSRVA
1
KYRRQ
6
VSEDP
11
DIDSL
16
LETLS
21
PEEME
26
ELEKE
31
LDVVD
36
PDGSV
41
PVGLR
46
QRNQT
51
EKQST
56
GVYNR
61
EAMLN
66
FCEKE
71
TKKLM
76
QREMS
81
MDESK
86
QVETK
91
TDAKN
96
GEERG
101
RDASK
106
KALGP
111
RRDSD
116
LGKEP
121
KRGGL
126
KKSFS
131
RDRDE
136
AGGKS
141
GEKPK
146
EEKII
151
RGIDK
156
GRVRA
161
AVDKK
166
EAGKD
171
GRGEE
176
RAVAT
181
KKEEE
186
KKGSD
191
RNTGL
196
SRDKD
201
KKREE
206
MKEVA
211
KKEDD
216
EKVKG
221
ERRNT
226
DTRKE
231
GEKMK
236
RAGGN
241
TDMKK
246
EDEKV
251
KRGTG
256
NTDTK
261
KDDEK
266
VKKNE
271
PLHEK
276
EAKDD
281
SKTKT
286
PEKQT
291
PSGPT
296
KPSEG
301
PAKVE
306
EEAAP
311
SIFDE
316
PLERV
321
KNNDP
326
EMTEV
331
NVNNS
336
DCITN
341
EILVR
346
FTEAL
351
EFNTV
356
VKLFA
361
LANTR
366
ADDHV
371
AFAIA
376
IMLKA
381
NKTIT
386
SLNLD
391
SNHIT
396
GKGIL
401
AIFRA
406
LLQNN
411
TLTEL
416
RFHNQ
421
RHICG
426
GKTEM
431
EIAKL
436
LKENT
441
TLLKL
446
GYHFE
451
LAGPR
456
MTVTN
461
LLSRN
466
MDKQR
471
QKRLQ
476
EQRQA
481
QEAKG
486
EKKDL
491
LEVPK
496
AGAVA
501
KGSPK
506
PSPQP
511
SPKPS
516
PKNSP
521
KKGGA
526
PAAPP
531
PPPPP
536
LAPPL
541
IMENL
546
KNSLS
551
PATQR
556
KMGDK
561
VLPAQ
566
EKNSR
571
DQLLA
576
AIRSS
581
NLKQL
586
KKVEV
591
PKLLQ
596
Mutation Information
DNA mutation:
c.C1561A
Peptide Range:
509 ~ 533
Mut AA position:
521 (13 in Wild Type peptide)
Alignment
Wild Type:
"PKPSPQPSPKPSPKNSPKKGGAPAA
||||||||||||.||||||||||||
Mutant:
PKPSPQPSPKPSTKNSPKKGGAPAA"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) LMOD1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay