Immunogenicity 15546
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
FRMPD1 (FPKM: 0.04)
Transcript ID
NM_014907
HLA INFO
C*16:01
TCR INFO
No TCR info found!
Full length protein sequence (1578 aa)
MEELE
1
TSLFQ
6
TRKAH
11
RIEQM
16
VARWL
21
RRSRD
26
SSARA
31
KVAAA
36
DGPAR
41
NPTQT
46
LIPVR
51
HTVKI
56
DKDTL
61
LQDYG
66
FHISE
71
SLPLT
76
VVAVT
81
AGGSA
86
HGKLF
91
PGDQI
96
LQMNN
101
EPAED
106
LSWER
111
AVDIL
116
REAED
121
SLSIT
126
VVRCT
131
SGVPK
136
SSFLT
141
EEKRA
146
RLKTN
151
PVKVH
156
FAEEV
161
LISGH
166
SQGNS
171
LLCMP
176
NVLKL
181
YLENG
186
QTKAF
191
KFEAN
196
TTVKD
201
IILTV
206
KEKLS
211
IRSIE
216
YFALA
221
LEEQY
226
SISRL
231
HLLHE
236
EELIQ
241
QVVER
246
EESHD
251
YRCLF
256
RVCFV
261
PKDPL
266
DLLKE
271
DPVAF
276
EYLYL
281
QSCSD
286
VLQER
291
FAVEM
296
KCSSA
301
LRLAA
306
LHIQE
311
RIYAC
316
AQPQK
321
ISLKY
326
IEKDW
331
GIENF
336
ISPTL
341
LRNMK
346
GKDIK
351
KAISF
356
HMKRN
361
QNLLE
366
PRQKQ
371
LISAA
376
QLRLN
381
YLQIL
386
GELKT
391
YGGRI
396
FNATL
401
MLQDR
406
ESYIA
411
LLVGA
416
KYGIS
421
QVINS
426
KLNIM
431
STLAE
436
FANIS
441
RVELT
446
EESEK
451
VSVVK
456
VYLQD
461
VKVLT
466
LLLES
471
NSAKD
476
LACLI
481
AGYYR
486
LLVDP
491
VTSIF
496
LWPGN
501
KQQAH
506
RVSAE
511
EGYES
516
RACSD
521
SEESS
526
EVDCV
531
LEPLS
536
DRRLV
541
KLAPC
546
RSLIK
551
EEQPP
556
GNSPT
561
PEVAR
566
RGPST
571
CGASS
576
TTDSA
581
ESEAS
586
DSANT
591
ESRGY
596
RTSGS
601
SESMD
606
ALEED
611
DLDTC
616
SSSRS
621
TFFHF
626
GSPGL
631
AESID
636
SDSQE
641
ERSGI
646
ETSGF
651
LCLLD
656
LAQRA
661
NPQCQ
666
KTEFS
671
ESAAL
676
ETFGW
681
APELS
686
TVRLD
691
PRLYE
696
GSHAD
701
YYSLC
706
SSVSP
711
ASYLS
716
DSSES
721
TASRQ
726
GGAPP
731
AWGQQ
736
GWTEA
741
QPSSM
746
LEPLA
751
LHPPL
756
AFEDG
761
SSDEE
766
YYDAA
771
DKLTP
776
PGPPS
781
GPRDV
786
STAEP
791
SATSL
796
QNKAS
801
TSSPE
806
NSLPC
811
GPDGR
816
QPSRR
821
GGVKK
826
YAKTL
831
RKRRS
836
FLQTD
841
YTSQV
846
SFPLV
851
PSASL
856
ESVDD
861
VCYYD
866
REPYL
871
ALGAP
876
SPTVS
881
SLQDM
886
QGEPG
891
LLETK
896
ALGLL
901
APLRE
906
TKSTN
911
PASRV
916
MEMEP
921
ETMET
926
KSVID
931
SRVSS
936
ISAIR
941
FRIDP
946
NNKEN
951
SGVVP
956
AASSS
961
ASTPH
966
CSNPG
971
SSGPD
976
TAQAR
981
PSQIL
986
PLSQD
991
LDGIA
996
PKEPT
1001
IEHGD
1006
SSFSL
1011
SSGDP
1016
NPDRA
1021
CLASN
1026
PGLNN
1031
VSQGD
1036
TLELQ
1041
LEPHV
1046
QLEMG
1051
LESFC
1056
TNHIQ
1061
ETAPK
1066
YTEPL
1071
LSPRD
1076
EPRSD
1081
ECGIN
1086
PGEKI
1091
ASIPT
1096
KEEPQ
1101
GQLSL
1106
ERDRE
1111
VTNKN
1116
GTNVF
1121
QEESR
1126
KDSGD
1131
SPGDV
1136
SNNVS
1141
QTLDI
1146
SSPAG
1151
KIVTS
1156
LSLDA
1161
PVTGT
1166
EQIPP
1171
HPPRD
1176
PQGQS
1181
REPPG
1186
QGCQA
1191
QEQKL
1196
FVELD
1201
LDPDF
1206
FLGKQ
1211
TVSPA
1216
VPPEG
1221
IKAEA
1226
PNHVT
1231
GQDIA
1236
PRDSP
1241
EWVCF
1246
NPEPS
1251
LPEPL
1256
PCPQE
1261
DPHLE
1266
TSNHC
1271
LLSEG
1276
KSDSS
1281
SICLS
1286
AEKSF
1291
LCFAP
1296
ESHPE
1301
VSASL
1306
RVATS
1311
LGFAG
1316
MNEMV
1321
APRIG
1326
MDQCS
1331
CQFSY
1336
ATCFR
1341
GPQPE
1346
TEEED
1351
RDLEA
1356
HPMAP
1361
LTSPP
1366
SAGSP
1371
VVLPW
1376
RPARA
1381
HSCTT
1386
APLSR
1391
KSHIW
1396
PEYCS
1401
RALRQ
1406
LKATP
1411
ASTPE
1416
GFIQL
1421
MESLL
1426
ELQDI
1431
LETSW
1436
GVGNK
1441
HPPEK
1446
CTWHF
1451
TESRS
1456
RLCMG
1461
SQKLL
1466
SSCRH
1471
VIRMD
1476
QSPEE
1481
MQGAV
1486
RDTFQ
1491
HLVQL
1496
AGLCF
1501
QFTDC
1506
SRCSA
1511
RHREA
1516
AGNLR
1521
DVVYT
1526
YHQFI
1531
EAAKS
1536
TCERG
1541
YHDLS
1546
VKLLA
1551
RQCTA
1556
LTAAV
1561
FCLTQ
1566
KFRAS
1571
TAL
1576
Mutation Information
DNA mutation:
c.C4685T
Peptide Range:
1550 ~ 1574
Mut AA position:
1562 (13 in Wild Type peptide)
Alignment
Wild Type:
"SVKLLARQCTALTAAVFCLTQKFRA
||||||||||||.||||||||||||
Mutant:
SVKLLARQCTALMAAVFCLTQKFRA"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) FRMPD1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay