Immunogenicity 15563

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
TRIM11 (FPKM: 20.87)
Transcript ID
NM_145214
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (468 aa)
MAAPD
1
LSTNL
6
QEEAT
11
CAICL
16
DYFTD
21
PVMTD
26
CGHNF
31
CRECI
36
RRCWG
41
QPEGP
46
YACPE
51
CRELS
56
PQRNL
61
RPNRP
66
LAKMA
71
EMARR
76
LHPPS
81
PVPQG
86
VCPAH
91
REPLA
96
AFCGD
101
ELRLL
106
CAACE
111
RSGEH
116
WAHRV
121
RPLQD
126
AAEDL
131
KAKLE
136
KSLEH
141
LRKQM
146
QDALL
151
FQAQA
156
DETCV
161
LWQKM
166
VESQR
171
QNVLG
176
EFERL
181
RRLLA
186
EEEQQ
191
LLQRL
196
EEEEL
201
EVLPR
206
LREGA
211
AHLGQ
216
QSAHL
221
AELIA
226
ELEGR
231
CQLPA
236
LGLLQ
241
DIKDA
246
LRRVQ
251
DVKLQ
256
PPEVV
261
PMELR
266
TVCRV
271
PGLVE
276
TLRRF
281
RGDVT
286
LDPDT
291
ANPEL
296
ILSED
301
RRSVQ
306
RGDLR
311
QALPD
316
SPERF
321
DPGPC
326
VLGQE
331
RFTSG
336
RHYWE
341
VEVGD
346
RTSWA
351
LGVCR
356
ENVNR
361
KEKGE
366
LSAGN
371
GFWIL
376
VFLGS
381
YYNSS
386
ERALA
391
PLRDP
396
PRRVG
401
IFLDY
406
EAGHL
411
SFYSA
416
TDGSL
421
LFIFP
426
EIPFS
431
GTLRP
436
LFSPL
441
SSSPT
446
PMTIC
451
RPKGG
456
SGDTL
461
APQ
466
Mutation Information
DNA mutation:
c.A368T
Peptide Range:
111 ~ 135
Mut AA position:
123 (13 in Wild Type peptide)
Alignment
Wild Type:
"CAACERSGEHWAHRVRPLQDAAEDL
||||||||||||.||||||||||||
Mutant:
CAACERSGEHWALRVRPLQDAAEDL"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) TRIM11

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay