Immunogenicity 15572
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
ZNF853 (FPKM: 2.13)
Transcript ID
NM_017560
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (659 aa)
MLHQP
1
TPGNR
6
GLTAR
11
MEVGP
16
ATETF
21
VLELQ
26
CLEDG
31
GPGPD
36
TLSGG
41
SGGSE
46
SQEEE
51
EPQER
56
NSSPQ
61
RPAVS
66
APVGA
71
SEIAE
76
ETRPG
81
QRELQ
86
LQQLE
91
QQPEP
96
QQQPQ
101
HEQLQ
106
QPQPH
111
LELQQ
116
QPQQD
121
GQQQL
126
SQLQQ
131
EKHQS
136
VHHQE
141
LKPEL
146
QLMHQ
151
QQQLQ
156
PQQVQ
161
EQQRL
166
QQQQE
171
QLQTQ
176
QAQEQ
181
QVLQQ
186
QEQLQ
191
QQVQE
196
QQLLQ
201
QQQEQ
206
LQQQQ
211
LLQQQ
216
EQLQQ
221
QQFQQ
226
QQEQL
231
QQQQQ
236
LLLLQ
241
QQGQL
246
QQQLL
251
QQQQA
256
QLQQQ
261
LLEQQ
266
QAQLQ
271
QQLLL
276
QQQEQ
281
LQQQQ
286
QQQLL
291
QQQQE
296
QLQQQ
301
QLQPP
306
PLEPE
311
EEEEV
316
ELELM
321
PVDLG
326
SEQEL
331
EQQRQ
336
ELERQ
341
QELER
346
QQEQR
351
QLQLK
356
LQEEL
361
QQLEQ
366
QLEQQ
371
QQQLE
376
QQEVQ
381
LELTP
386
VELGA
391
QQQEV
396
QLELT
401
PVQPE
406
LQLEL
411
VPAAG
416
GGGAA
421
VPGAP
426
AAVVV
431
APPGY
436
VVVQE
441
LMVLP
446
AVAAP
451
AVVAI
456
PGPAG
461
SAALT
466
PARQR
471
RRRRA
476
RDRPT
481
ICGEC
486
GKGFS
491
RSTDL
496
VRHQA
501
THTGE
506
RPHRC
511
GECGK
516
GFSQH
521
SNLVT
526
HQRIH
531
TGEKP
536
YACSY
541
CAKRF
546
SESSA
551
LVQHQ
556
RTHTG
561
ERPYA
566
CGDCG
571
KRFSV
576
SSNLL
581
RHRRT
586
HSGER
591
PYVCE
596
DCGER
601
FRHKV
606
QIRRH
611
ERQLH
616
GAGRS
621
RGLGL
626
LRASR
631
PAALG
636
GPARA
641
EQAAT
646
ATAPA
651
DKAL
656
Mutation Information
DNA mutation:
c.G1369A
Peptide Range:
445 ~ 469
Mut AA position:
457 (13 in Wild Type peptide)
Alignment
Wild Type:
"ELMVLPAVAAPAVVAIPGPAGSAAL
||||||||||||.||||||||||||
Mutant:
ELMVLPAVAAPAMVAIPGPAGSAAL"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) ZNF853
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay