Immunogenicity 15590

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
ESRRA (FPKM: 19.43)
Transcript ID
NM_001282450
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (423 aa)
MSSQV
1
VGIEP
6
LYIKA
11
EPASP
16
DSPKG
21
SSETE
26
TEPPV
31
ALAPG
36
PAPTR
41
CLPGH
46
KEEED
51
GEGAG
56
PGEQG
61
GGKLV
66
LSSLP
71
KRLCL
76
VCGDV
81
ASGYH
86
YGVAS
91
CEACK
96
AFFKR
101
TIQGS
106
IEYSC
111
PASNE
116
CEITK
121
RRRKA
126
CQACR
131
FTKCL
136
RVGML
141
KEGVR
146
LDRVR
151
GGRQK
156
YKRRP
161
EVDPL
166
PFPGP
171
FPAGP
176
LAVAG
181
GPRKT
186
AAPVN
191
ALVSH
196
LLVVE
201
PEKLY
206
AMPDP
211
AGPDG
216
HLPAV
221
ATLCD
226
LFDRE
231
IVVTI
236
SWAKS
241
IPGFS
246
SLSLS
251
DQMSV
256
LQSVW
261
MEVLV
266
LGVAQ
271
RSLPL
276
QDELA
281
FAEDL
286
VLDEE
291
GARAA
296
GLGEL
301
GAALL
306
QLVRR
311
LQALR
316
LEREE
321
YVLLK
326
ALALA
331
NSDSV
336
HIEDA
341
EAVEQ
346
LREAL
351
HEALL
356
EYEAG
361
RAGPG
366
GGAER
371
RRAGR
376
LLLTL
381
PLLRQ
386
TAGKV
391
LAHFY
396
GVKLE
401
GKVPM
406
HKLFL
411
EMLEA
416
MMD
421
Mutation Information
DNA mutation:
c.C518T
Peptide Range:
161 ~ 185
Mut AA position:
173 (13 in Wild Type peptide)
Alignment
Wild Type:
"YKRRPEVDPLPFPGPFPAGPLAVAG
||||||||||||.||||||||||||
Mutant:
YKRRPEVDPLPFLGPFPAGPLAVAG"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) ESRRA

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay