Immunogenicity 15612
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PEX1 (FPKM: 9.6)
Transcript ID
NM_000466
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1283 aa)
MWGSD
1
RLAGA
6
GGGGA
11
AVTVA
16
FTNAR
21
DCFLH
26
LPRRL
31
VAQLH
36
LLQNQ
41
AIEVV
46
WSHQP
51
AFLSW
56
VEGRH
61
FSDQG
66
ENVAE
71
INRQV
76
GQKLG
81
LSNGG
86
QVFLK
91
PCSHV
96
VSCQQ
101
VEVEP
106
LSADD
111
WEILE
116
LHAVS
121
LEQHL
126
LDQIR
131
IVFPK
136
AIFPV
141
WVDQQ
146
TYIFI
151
QIVAL
156
IPAAS
161
YGRLE
166
TDTKL
171
LIQPK
176
TRRAK
181
ENTFS
186
KADAE
191
YKKLH
196
SYGRD
201
QKGMM
206
KELQT
211
KQLQS
216
NTVGI
221
TESNE
226
NESEI
231
PVDSS
236
SVASL
241
WTMIG
246
SIFSF
251
QSEKK
256
QETSW
261
GLTEI
266
NAFKN
271
MQSKV
276
VPLDN
281
IFRVC
286
KSQPP
291
SIYNA
296
SATSV
301
FHKHC
306
AIHVF
311
PWDQE
316
YFDVE
321
PSFTV
326
TYGKL
331
VKLLS
336
PKQQQ
341
SKTKQ
346
NVLSP
351
EKEKQ
356
MSEPL
361
DQKKI
366
RSDHN
371
EEDEK
376
ACVLQ
381
VVWNG
386
LEELN
391
NAIKY
396
TKNVE
401
VLHLG
406
KVWIP
411
DDLRK
416
RLNIE
421
MHAVV
426
RITPV
431
EVTPK
436
IPRSL
441
KLQPR
446
ENLPK
451
DISEE
456
DIKTV
461
FYSWL
466
QQSTT
471
TMLPL
476
VISEE
481
EFIKL
486
ETKDG
491
LKEFS
496
LSIVH
501
SWEKE
506
KDKNI
511
FLLSP
516
NLLQK
521
TTIQV
526
LLDPM
531
VKEEN
536
SEEID
541
FILPF
546
LKLSS
551
LGGVN
556
SLGVS
561
SLEHI
566
THSLL
571
GRPLS
576
RQLMS
581
LVAGL
586
RNGAL
591
LLTGG
596
KGSGK
601
STLAK
606
AICKE
611
AFDKL
616
DAHVE
621
RVDCK
626
ALRGK
631
RLENI
636
QKTLE
641
VAFSE
646
AVWMQ
651
PSVVL
656
LDDLD
661
LIAGL
666
PAVPE
671
HEHSP
676
DAVQS
681
QRLAH
686
ALNDM
691
IKEFI
696
SMGSL
701
VALIA
706
TSQSQ
711
QSLHP
716
LLVSA
721
QGVHI
726
FQCVQ
731
HIQPP
736
NQEQR
741
CEILC
746
NVIKN
751
KLDCD
756
INKFT
761
DLDLQ
766
HVAKE
771
TGGFV
776
ARDFT
781
VLVDR
786
AIHSR
791
LSRQS
796
ISTRE
801
KLVLT
806
TLDFQ
811
KALRG
816
FLPAS
821
LRSVN
826
LHKPR
831
DLGWD
836
KIGGL
841
HEVRQ
846
ILMDT
851
IQLPA
856
KYPEL
861
FANLP
866
IRQRT
871
GILLY
876
GPPGT
881
GKTLL
886
AGVIA
891
RESRM
896
NFISV
901
KGPEL
906
LSKYI
911
GASEQ
916
AVRDI
921
FIRAQ
926
AAKPC
931
ILFFD
936
EFESI
941
APRRG
946
HDNTG
951
VTDRV
956
VNQLL
961
TQLDG
966
VEGLQ
971
GVYVL
976
AATSR
981
PDLID
986
PALLR
991
PGRLD
996
KCVYC
1001
PPPDQ
1006
VSRLE
1011
ILNVL
1016
SDSLP
1021
LADDV
1026
DLQHV
1031
ASVTD
1036
SFTGA
1041
DLKAL
1046
LYNAQ
1051
LEALH
1056
GMLLS
1061
SGLQD
1066
GSSSS
1071
DSDLS
1076
LSSMV
1081
FLNHS
1086
SGSDD
1091
SAGDG
1096
ECGLD
1101
QSLVS
1106
LEMSE
1111
ILPDE
1116
SKFNM
1121
YRLYF
1126
GSSYE
1131
SELGN
1136
GTSSD
1141
LSSQC
1146
LSAPS
1151
SMTQD
1156
LPGVP
1161
GKDQL
1166
FSQPP
1171
VLRTA
1176
SQEGC
1181
QELTQ
1186
EQRDQ
1191
LRADI
1196
SIIKG
1201
RYRSQ
1206
SGEDE
1211
SMNQP
1216
GPIKT
1221
RLAIS
1226
QSHLM
1231
TALGH
1236
TRPSI
1241
SEDDW
1246
KNFAE
1251
LYESF
1256
QNPKR
1261
RKNQS
1266
GTMFR
1271
PGQKV
1276
TLA
1281
Mutation Information
DNA mutation:
c.C235G
Peptide Range:
67 ~ 91
Mut AA position:
79 (13 in Wild Type peptide)
Alignment
Wild Type:
"SDQGENVAEINRQVGQKLGLSNGGQ
||||||||||||.||||||||||||
Mutant:
SDQGENVAEINREVGQKLGLSNGGQ"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) PEX1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay