Immunogenicity 15625

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
PCDHB3 (FPKM: 0.23)
Transcript ID
NM_018937
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (796 aa)
MEAGG
1
ERFLR
6
QRQVL
11
LLFVF
16
LGGSL
21
AGSES
26
RRYSV
31
AEEKE
36
KGFLI
41
ANLAK
46
DLGLR
51
VEELA
56
ARGAQ
61
VVSKG
66
NKQHF
71
QLSHQ
76
TGDLL
81
LNEKL
86
DREEL
91
CGPTE
96
PCILH
101
FQILL
106
QNPLQ
111
FVTNE
116
LRIID
121
VNDHS
126
PVFFE
131
NEMHL
136
KILES
141
TLPGT
146
VIPLG
151
NAEDL
156
DVGRN
161
SLQNY
166
TITPN
171
SHFHV
176
LTRSR
181
RDGRK
186
YPELV
191
LDKAL
196
DREEQ
201
PELSL
206
TLTAL
211
DGGSP
216
PRSGT
221
AQINI
226
QVLDI
231
NDNAP
236
EFAQP
241
LYEVA
246
VLENT
251
PVNSV
256
IVTVS
261
ASDLD
266
TGSFG
271
TISYA
276
FFHAS
281
EEIRK
286
TFQLN
291
PITGD
296
MQLVK
301
YLNFE
306
AINSY
311
EVDIE
316
AKDGG
321
GLSGK
326
STVIV
331
QVVDV
336
NDNPP
341
ELTLS
346
SVNSP
351
IPENS
356
GETVL
361
AVFSV
366
SDLDS
371
GDNGR
376
VMCSI
381
ENNLP
386
FFLKP
391
SVENF
396
YTLVS
401
EGALD
406
RETRS
411
EYNIT
416
ITITD
421
LGTPR
426
LKTKY
431
NITVL
436
VSDVN
441
DNAPA
446
FTQIS
451
YTLFV
456
RENNS
461
PALHI
466
GSVSA
471
TDRDS
476
GTNAQ
481
VTYSL
486
LPPQD
491
PHLPL
496
SSLVS
501
INADN
506
GHLFA
511
LRSLD
516
YEALQ
521
AFEFR
526
VGATD
531
RGSPA
536
LSSEA
541
LVRVL
546
VLDAN
551
DNSPF
556
VLYPL
561
QNGSA
566
PCTEL
571
VPRAA
576
EPGYL
581
VTKVV
586
AVDGD
591
SGQNA
596
WLSYQ
601
LLKAT
606
EPGLF
611
GVWAH
616
NGEVR
621
TARLL
626
SERDA
631
AKHRL
636
VVLVK
641
DNGEP
646
PRSAT
651
ATLHV
656
LLVDG
661
FSQPY
666
LPLPE
671
AAPAQ
676
AQADL
681
LTVYL
686
VVALA
691
SVSSL
696
FLFSV
701
LLFVA
706
VRLCR
711
RSRAA
716
SVGRC
721
SVPEG
726
PFPGQ
731
MVDVS
736
GTGTL
741
SQSYQ
746
YEVCL
751
TGGSG
756
TNEFK
761
FLKPI
766
IPNFV
771
AQGAE
776
RVSEA
781
NPSFR
786
KSFEF
791
S
796
Mutation Information
DNA mutation:
c.G958A
Peptide Range:
308 ~ 332
Mut AA position:
320 (13 in Wild Type peptide)
Alignment
Wild Type:
"NFEAINSYEVDIEAKDGGGLSGKST
||||||||||||.||||||||||||
Mutant:
NFEAINSYEVDIKAKDGGGLSGKST"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) PCDHB3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay