Immunogenicity 15641

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
KLF5 (FPKM: 343.69)
Transcript ID
NM_001286818
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (366 aa)
MEKYL
1
TPQLP
6
PVPII
11
PEHKK
16
YRRDS
21
ASVVD
26
QFFTD
31
TEGLP
36
YSINM
41
NVFLP
46
DITHL
51
RTGLY
56
KSQRP
61
CVTHI
66
KTEPV
71
AIFSH
76
QSETT
81
APPPA
86
PTQAL
91
PEFTS
96
IFSSH
101
QTAAP
106
EVNNI
111
FIKQE
116
LPTPD
121
LHLSV
126
PTQQG
131
HLYQL
136
LNTPD
141
LDMPS
146
STNQT
151
AAMDT
156
LNVSM
161
SAAMA
166
GLNTH
171
TSAVP
176
QTAVK
181
QFQGM
186
PPCTY
191
TMPSQ
196
FLPQQ
201
ATYFP
206
PSPPS
211
SEPGS
216
PDRQA
221
EMLQN
226
LTPPP
231
SYAAT
236
IASKL
241
AIHNP
246
NLPTT
251
LPVNS
256
QNIQP
261
VRYNR
266
RSNPD
271
LEKRR
276
IHYCD
281
YPGCT
286
KVYTK
291
SSHLK
296
AHLRT
301
HTGEK
306
PYKCT
311
WEGCD
316
WRFAR
321
SDELT
326
RHYRK
331
HTGAK
336
PFQCG
341
VCNRS
346
FSRSD
351
HLALH
356
MKRHQ
361
N
366
Mutation Information
DNA mutation:
c.C652G
Peptide Range:
206 ~ 230
Mut AA position:
218 (13 in Wild Type peptide)
Alignment
Wild Type:
"ATYFPPSPPSSEPGSPDRQAEMLQN
||||||||||||.||||||||||||
Mutant:
ATYFPPSPPSSEAGSPDRQAEMLQN"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) KLF5

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay