Immunogenicity 15642
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
ROBO2 (FPKM: 3.89)
Transcript ID
NM_001290039
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1382 aa)
MSLLM
1
FTQLL
6
LCGFL
11
YVRVD
16
GSRLR
21
QEDFP
26
PRIVE
31
HPSDV
36
IVSKG
41
EPTTL
46
NCKAE
51
GRPTP
56
TIEWY
61
KDGER
66
VETDK
71
DDPRS
76
HRMLL
81
PSGSL
86
FFLRI
91
VHGRR
96
SKPDE
101
GSYVC
106
VARNY
111
LGEAV
116
SRNAS
121
LEVAL
126
LRDDF
131
RQNPT
136
DVVVA
141
AGEPA
146
ILECQ
151
PPRGH
156
PEPTI
161
YWKKD
166
KVRID
171
DKEER
176
ISIRG
181
GKLMI
186
SNTRK
191
SDAGM
196
YTCVG
201
TNMVG
206
ERDSD
211
PAELT
216
VFERP
221
TFLRR
226
PINQV
231
VLEEE
236
AVEFR
241
CQVQG
246
DPQPT
251
VRWKK
256
DDADL
261
PRGRY
266
DIKDD
271
YTLRI
276
KKTMS
281
TDEGT
286
YMCIA
291
ENRVG
296
KMEAS
301
ATLTV
306
RARPV
311
APPQF
316
VVRPR
321
DQIVA
326
QGRTV
331
TFPCE
336
TKGNP
341
QPAVF
346
WQKEG
351
SQNLL
356
FPNQP
361
QQPNS
366
RCSVS
371
PTGDL
376
TITNI
381
QRSDA
386
GYYIC
391
QALTV
396
AGSIL
401
AKAQL
406
EVTDV
411
LTDRP
416
PPIIL
421
QGPAN
426
QTLAV
431
DGTAL
436
LKCKA
441
TGDPL
446
PVISW
451
LKEGF
456
TFPGR
461
DPRAT
466
IQEQG
471
TLQIK
476
NLRIS
481
DTGTY
486
TCVAT
491
SSSGE
496
TSWSA
501
VLDVT
506
ESGAT
511
ISKNY
516
DLSDL
521
PGPPS
526
KPQVT
531
DVTKN
536
SVTLS
541
WQPGT
546
PGTLP
551
ASAYI
556
IEAFS
561
QSVSN
566
SWQTV
571
ANHVK
576
TTLYT
581
VRGLR
586
PNTIY
591
LFMVR
596
AINPQ
601
GLSDP
606
SPMSD
611
PVRTQ
616
DISPP
621
AQGVD
626
HRQVQ
631
KELGD
636
VLVRL
641
HNPVV
646
LTPTT
651
VQVTW
656
TVDRQ
661
PQFIQ
666
GYRVM
671
YRQTS
676
GLQAT
681
SSWQN
686
LDAKV
691
PTERS
696
AVLVN
701
LKKGV
706
TYEIK
711
VRPYF
716
NEFQG
721
MDSES
726
KTVRT
731
TEEAP
736
SAPPQ
741
SVTVL
746
TVGSY
751
NSTSI
756
SVSWD
761
PPPPD
766
HQNGI
771
IQEYK
776
IWCLG
781
NETRF
786
HINKT
791
VDAAI
796
RSVII
801
GGLFP
806
GIQYR
811
VEVAA
816
STSAG
821
VGVKS
826
EPQPI
831
IIGRR
836
NEVVI
841
TENNN
846
SITEQ
851
ITDVV
856
KQPAF
861
IAGIG
866
GACWV
871
ILMGF
876
SIWLY
881
WRRKK
886
RKGLS
891
NYAVT
896
FQRGD
901
GGLMS
906
NGSRP
911
GLLNA
916
GDPSY
921
PWLAD
926
SWPAT
931
SLPVN
936
NSNSG
941
PNEIG
946
NFGRG
951
DVLPP
956
VPGQG
961
DKTAT
966
MLSDG
971
AIYSS
976
IDFTT
981
KTSYN
986
SSSQI
991
TQATP
996
YATTQ
1001
ILHSN
1006
SIHEL
1011
AVDLP
1016
DPQWK
1021
SSIQQ
1026
KTDLM
1031
GFGYS
1036
LPDQN
1041
KGNNG
1046
GKGGK
1051
KKKNK
1056
NSSKP
1061
QKNNG
1066
STWAN
1071
VPLPP
1076
PPVQP
1081
LPGTE
1086
LEHYA
1091
VEQQE
1096
NGYDS
1101
DSWCP
1106
PLPVQ
1111
TYLHQ
1116
GLEDE
1121
LEEDD
1126
DRVPT
1131
PPVRG
1136
VASSP
1141
AISFG
1146
QQSTA
1151
TLTPS
1156
PREEM
1161
QPMLQ
1166
AHLDE
1171
LTRAY
1176
QFDIA
1181
KQTWH
1186
IQSNN
1191
QPPQP
1196
PVPPL
1201
GYVSG
1206
ALISD
1211
LETDV
1216
ADDDA
1221
DDEEE
1226
ALEIP
1231
RPLRA
1236
LDQTP
1241
GSSMD
1246
NLDSS
1251
VTGKA
1256
FTSSQ
1261
RPRPT
1266
SPFST
1271
DSNTS
1276
AALSQ
1281
SQRPR
1286
PTKKH
1291
KGGRM
1296
DQQPA
1301
LPHRR
1306
EGMTD
1311
EEALV
1316
PYSKP
1321
SFPSP
1326
GGHSS
1331
SGTAS
1336
SKGST
1341
GPRKT
1346
EVLRA
1351
GHQRN
1356
ASDLL
1361
DIGYM
1366
GSNSQ
1371
GQFTG
1376
EL
1381
Mutation Information
DNA mutation:
c.C2797A
Peptide Range:
921 ~ 945
Mut AA position:
933 (13 in Wild Type peptide)
Alignment
Wild Type:
"GDPSYPWLADSWPATSLPVNNSNSG
||||||||||||.||||||||||||
Mutant:
GDPSYPWLADSWTATSLPVNNSNSG"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) ROBO2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay