Immunogenicity 15659

summary
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
MCHR2 (FPKM: 0)
Transcript ID
NM_001040179
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (340 aa)
MNPFH
1
ASCWN
6
TSAEL
11
LNKSW
16
NKEFA
21
YQTAS
26
VVDTV
31
ILPSM
36
IGIIC
41
STGLV
46
GNILI
51
VFTII
56
RSRKK
61
TVPDI
66
YICNL
71
AVADL
76
VHIVG
81
MPFLI
86
HQWAR
91
GGEWV
96
FGGPL
101
CTIIT
106
SLDTC
111
NQFAC
116
SAIMT
121
VMSVD
126
RYFAL
131
VQPFR
136
LTRWR
141
TRYKT
146
IRINL
151
GLWAA
156
SFILA
161
LPVWV
166
YSKVI
171
KFKDG
176
VESCA
181
FDLTS
186
PDDVL
191
WYTLY
196
LTITT
201
FFFPL
206
PLILV
211
CYILI
216
LCYTW
221
EMYQQ
226
NKDAR
231
CCNPS
236
VPKQR
241
VMKLT
246
KMVLV
251
LVVVF
256
ILSAA
261
PYHVI
266
QLVNL
271
QMEQP
276
TLAFY
281
VGYYL
286
SICLS
291
YASSS
296
INPFL
301
YILLS
306
GNFQK
311
RLPQI
316
QRRAT
321
EKEIN
326
NMGNT
331
LKSHF
336
Mutation Information
DNA mutation:
c.A347C
Peptide Range:
104 ~ 128
Mut AA position:
116 (13 in Wild Type peptide)
Alignment
Wild Type:
"PLCTIITSLDTCNQFACSAIMTVMS
||||||||||||.||||||||||||
Mutant:
PLCTIITSLDTCTQFACSAIMTVMS"
reference

N Engl J Med, 2016

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

Gene Name (from Reference) MCHR2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

DCs

Assay

IFNg ELISPOT assay