Immunogenicity 15669
Sample ID
4095
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
LRRC4 (FPKM: 1.24)
Transcript ID
NM_022143
HLA INFO
B*14:02
TCR INFO
No TCR info found!
Full length protein sequence (653 aa)
MKLLW
1
QVTVH
6
HHTWN
11
AILLP
16
FVYLT
21
AQVWI
26
LCAAI
31
AAAAS
36
AGPQN
41
CPSVC
46
SCSNQ
51
FSKVV
56
CTRRG
61
LSEVP
66
QGIPS
71
NTRYL
76
NLMEN
81
NIQMI
86
QADTF
91
RHLHH
96
LEVLQ
101
LGRNS
106
IRQIE
111
VGAFN
116
GLASL
121
NTLEL
126
FDNWL
131
TVIPS
136
GAFEY
141
LSKLR
146
ELWLR
151
NNPIE
156
SIPSY
161
AFNRV
166
PSLMR
171
LDLGE
176
LKKLE
181
YISEG
186
AFEGL
191
FNLKY
196
LNLGM
201
CNIKD
206
MPNLT
211
PLVGL
216
EELEM
221
SGNHF
226
PEIRP
231
GSFHG
236
LSSLK
241
KLWVM
246
NSQVS
251
LIERN
256
AFDGL
261
ASLVE
266
LNLAH
271
NNLSS
276
LPHDL
281
FTPLR
286
YLVEL
291
HLHHN
296
PWNCD
301
CDILW
306
LAWWL
311
REYIP
316
TNSTC
321
CGRCH
326
APMHM
331
RGRYL
336
VEVDQ
341
ASFQC
346
SAPFI
351
MDAPR
356
DLNIS
361
EGRMA
366
ELKCR
371
TPPMS
376
SVKWL
381
LPNGT
386
VLSHA
391
SRHPR
396
ISVLN
401
DGTLN
406
FSHVL
411
LSDTG
416
VYTCM
421
VTNVA
426
GNSNA
431
SAYLN
436
VSTAE
441
LNTSN
446
YSFFT
451
TVTVE
456
TTEIS
461
PEDTT
466
RKYKP
471
VPTTS
476
TGYQP
481
AYTTS
486
TTVLI
491
QTTRV
496
PKQVA
501
VPATD
506
TTDKM
511
QTSLD
516
EVMKT
521
TKIII
526
GCFVA
531
VTLLA
536
AAMLI
541
VFYKL
546
RKRHQ
551
QRSTV
556
TAART
561
VEIIQ
566
VDEDI
571
PAATS
576
AAATA
581
APSGV
586
SGEGA
591
VVLPT
596
IHDHI
601
NYNTY
606
KPAHG
611
AHWTE
616
NSLGN
621
SLHPT
626
VTTIS
631
EPYII
636
QTHTK
641
DKVQE
646
TQI
651
Mutation Information
DNA mutation:
c.C440A
Peptide Range:
135 ~ 159
Mut AA position:
147 (13 in Wild Type peptide)
Alignment
Wild Type:
"LTVIPSGAFEYLSKLRELWLRNNPI
||||||||||||.||||||||||||
Mutant:
LTVIPSGAFEYLYKLRELWLRNNPI"
N Engl J Med, 2016
T-Cell Transfer Therapy Targeting Mutant KRAS in CancerGene Name (from Reference) LRRC4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
IFNg ELISPOT assay