Immunogenicity 1568
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
PTPRM
Transcript ID
ENST00000332175
HLA INFO
B*44:03
TCR INFO
No TCR info found!
Full length protein sequence (1452 aa)
MRGLG
1
TCLAT
6
LAGLL
11
LTAAG
16
ETFSG
21
GCLFD
26
EPYST
31
CGYSQ
36
SEGDD
41
FNWEQ
46
VNTLT
51
KPTSD
56
PWMPS
61
GSFML
66
VNASG
71
RPEGQ
76
RAHLL
81
LPQLK
86
ENDTH
91
CIDFH
96
YFVSS
101
KSNSP
106
PGLLN
111
VYVKV
116
NNGPL
121
GNPIW
126
NISGD
131
PTRTW
136
NRAEL
141
AISTF
146
WPNFY
151
QVIFE
156
VITSG
161
HQGYL
166
AIDEV
171
KVLGH
176
PCTRT
181
PHFLR
186
IQNVE
191
VNAGQ
196
FATFQ
201
CSAIG
206
RTVAG
211
DRLWL
216
QGIDV
221
RDAPL
226
KEIKV
231
TSSRR
236
FIASF
241
NVVNT
246
TKRDA
251
GKYRC
256
MIRTE
261
GGVGI
266
SNYAE
271
LVVKE
276
PPVPI
281
APPQL
286
ASVGA
291
TYLWI
296
QLNAN
301
SINGD
306
GPIVA
311
REVEY
316
CTASG
321
SWNDR
326
QPVDS
331
TSYKI
336
GHLDP
341
DTEYE
346
ISVLL
351
TRPGE
356
GGTGS
361
PGPAL
366
RTRTK
371
CADPM
376
RGPRK
381
LEVVE
386
VKSRQ
391
ITIRW
396
EPFGY
401
NVTRC
406
HSYNL
411
TVHYC
416
YQVGG
421
QEQVR
426
EEVSW
431
DTENS
436
HPQHT
441
ITNLS
446
PYTNV
451
SVKLI
456
LMNPE
461
GRKES
466
QELIV
471
QTDED
476
LPGAV
481
PTESI
486
QGSTF
491
EEKIF
496
LQWRE
501
PTQTY
506
GVITL
511
YEITY
516
KAVSS
521
FDPEI
526
DLSNQ
531
SGRVS
536
KLGNE
541
THFLF
546
FGLYP
551
GTTYS
556
FTIRA
561
STAKG
566
FGPPA
571
TNQFT
576
TKISA
581
PSMPA
586
YELET
591
PLNQT
596
DNTVT
601
VMLKP
606
AHSRG
611
APVSV
616
YQIVV
621
EEERP
626
RRTKK
631
TTEIL
636
KCYPV
641
PIHFQ
646
NASLL
651
NSQYY
656
FAAEF
661
PADSL
666
QAAQP
671
FTIGD
676
NKTYN
681
GYWNT
686
PLLPY
691
KSYRI
696
YFQAA
701
SRANG
706
ETKID
711
CVQVA
716
TKGAA
721
TPKPV
726
PEPEK
731
QTDHT
736
VKIAG
741
VIAGI
746
LLFVI
751
IFLGV
756
VLVMK
761
KRKLA
766
KKRKE
771
TMSST
776
RQEMT
781
VMVNS
786
MDKSY
791
AEQGT
796
NCDEA
801
FSFMD
806
THNLN
811
GRSVS
816
SPSSF
821
TMKTN
826
TLSTS
831
VPNSY
836
YPDET
841
HTMAS
846
DTSSL
851
VQSHT
856
YKKRE
861
PADVP
866
YQTGQ
871
LHPAI
876
RVADL
881
LQHIT
886
QMKCA
891
EGYGF
896
KEEYE
901
SFFEG
906
QSAPW
911
DSAKK
916
DENRM
921
KNRYG
926
NIIAY
931
DHSRV
936
RLQTI
941
EGDTN
946
SDYIN
951
GNYID
956
GYHRP
961
NHYIA
966
TQGPM
971
QETIY
976
DFWRM
981
VWHEN
986
TASII
991
MVTNL
996
VEVGR
1001
VKCCK
1006
YWPDD
1011
TEIYK
1016
DIKVT
1021
LIETE
1026
LLAEY
1031
VIRTF
1036
AVEKR
1041
GVHEI
1046
REIRQ
1051
FHFTG
1056
WPDHG
1061
VPYHA
1066
TGLLG
1071
FVRQV
1076
KSKSP
1081
PSAGP
1086
LVVHC
1091
SAGAG
1096
RTGCF
1101
IVIDI
1106
MLDMA
1111
EREGV
1116
VDIYN
1121
CVREL
1126
RSRRV
1131
NMVQT
1136
EEQYV
1141
FIHDA
1146
ILEAC
1151
LCGDT
1156
SVPAS
1161
QVRSL
1166
YYDMN
1171
KLDPQ
1176
TNSSQ
1181
IKEEF
1186
RTLNM
1191
VTPTL
1196
RVEDC
1201
SIALL
1206
PRNHE
1211
KNRCM
1216
DILPP
1221
DRCLP
1226
FLITI
1231
DGESS
1236
NYINA
1241
ALMDS
1246
YKQPS
1251
AFIVT
1256
QHPLP
1261
NTVKD
1266
FWRLV
1271
LDYHC
1276
TSVVM
1281
LNDVD
1286
PAQLC
1291
PQYWP
1296
ENGVH
1301
RHGPI
1306
QVEFV
1311
SADLE
1316
EDIIS
1321
RIFRI
1326
YNAAR
1331
PQDGY
1336
RMVQQ
1341
FQFLG
1346
WPMYR
1351
DTPVS
1356
KRSFL
1361
KLIRQ
1366
VDKWQ
1371
EEYNG
1376
GEGRT
1381
VVHCL
1386
NGGGR
1391
SGTFC
1396
AISIV
1401
CEMLR
1406
HQRTV
1411
DVFHA
1416
VKTLR
1421
NNKPN
1426
MVDLL
1431
DQYKF
1436
CYEVA
1441
LEYLN
1446
SG
1451
Mutation Information
DNA mutation:
None
Peptide Range:
794 ~ 818
Mut AA position:
806 (13 in Wild Type peptide)
Alignment
Wild Type:
"SYAEQGTNCDEAFSFMDTHNLNGRS
||||||||||||.||||||||||||
Mutant:
SYAEQGTNCDEAVSFMDTHNLNGRS"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PTPRM
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay