Immunogenicity 15698
Sample ID
L012
Response
Positive
Tumor Type
NSC Lung cancer
Gene Symbol
CHTF18
Transcript ID
None
HLA INFO
A*11:01
TCR INFO
No TCR info found!
Full length protein sequence (976 aa)
MEDYE
1
QELCG
6
VEDDF
11
HNQFA
16
AELEV
21
LAELE
26
AGAST
31
PSPSG
36
VPLFT
41
AGRPP
46
RTFEE
51
ALARG
56
DAASS
61
PAPAA
66
SVGSS
71
QGGAR
76
KRQVD
81
ADLQP
86
AGSLP
91
HAPRI
96
KRPRL
101
QVVKR
106
LNFRS
111
EEMEE
116
PPPPD
121
SSPTD
126
ITPPP
131
SPEDL
136
AELWG
141
HGVSE
146
AAADV
151
GLTRA
156
SPAAR
161
NPVLR
166
RPPIL
171
EDYVH
176
VTSTE
181
GVRAY
186
LVLRA
191
DPMAP
196
GVQGS
201
LLHVP
206
WRGGG
211
QLDLL
216
GVSLA
221
SLKKQ
226
VDGER
231
RERLL
236
QEAQK
241
LSDTL
246
HSLRS
251
GEEEA
256
AQPLG
261
APEEE
266
PTDGQ
271
DASSH
276
CLWVD
281
EFAPR
286
HYTEL
291
LSDDF
296
TNRCL
301
LKWLK
306
LWDLV
311
VFGHE
316
RPSRK
321
PRPSV
326
EPARV
331
SKEAT
336
APGKW
341
KSHEQ
346
VLEEM
351
LEAGL
356
DPSQR
361
PKQKV
366
ALLCG
371
PPGLG
376
KTTLA
381
HVIAR
386
HAGYS
391
VVEMN
396
ASDDR
401
SPEVF
406
RTRIE
411
AATQM
416
ESVLG
421
AGGKP
426
NCLVI
431
DEIDG
436
APVAA
441
INVLL
446
SILNR
451
KGPQE
456
VGPQG
461
PAVPS
466
GGGRR
471
RRAEG
476
GLLMR
481
PIICI
486
CNDQF
491
APSLR
496
QLKQQ
501
AFLLH
506
FPPTL
511
PSRLV
516
QRLQE
521
VSLRQ
526
GMRAD
531
PGVLA
536
ALCEK
541
TDNDI
546
RACIN
551
TLQFL
556
YSRGQ
561
RELSV
566
RDVQA
571
TRVGL
576
KDQRR
581
GLFSV
586
WQEVF
591
QLPRA
596
QRRRV
601
GQDPA
606
LPADT
611
LLLGD
616
GDAGS
621
LTSAS
626
QRFYR
631
VLHAA
636
ASAGE
641
HEKVV
646
QGLFD
651
NFLRL
656
RLRDS
661
SLGAV
666
CVALD
671
WLAFD
676
DLLAG
681
AAHHS
686
QSFQL
691
LRYPP
696
FLPVA
701
FHVLF
706
ASSHT
711
PRITF
716
PSSQQ
721
EAQNR
726
MSQMR
731
NLIQT
736
LVSGI
741
APATR
746
SRATP
751
QALLL
756
DALCL
761
LLDIL
766
APKLR
771
PVSTQ
776
LYSTR
781
EKQQL
786
ASLVG
791
TMLAY
796
SLTYR
801
QERTP
806
DGQYI
811
YRLEP
816
NVEEL
821
CRFPE
826
LPARK
831
PLTYQ
836
TKQLI
841
AREIE
846
VEKMR
851
RAEAS
856
ARVEN
861
SPQVD
866
GSPPG
871
LEGLL
876
GGIGE
881
KGVHR
886
PAPRN
891
HEQRL
896
EHIMR
901
RAARE
906
EQPEK
911
DFFGR
916
VVVRS
921
TAVPS
926
AGDTA
931
PEQDS
936
VERRM
941
GTAVG
946
RSEVW
951
FRFNE
956
GVSNA
961
VRRSL
966
YIRDL
971
L
976
Mutation Information
DNA mutation:
None
Peptide Range:
766 ~ 773
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"LLDILAPK
||||.|||
Mutant:
LLDIVAPK"
Science, 2016
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockadeGene Name (from Reference) CHTF18
Checkpoint
Blockade
pembrolizumab
ACT
N
Vaccination
N
Curative
Effect
clinical benefit
minimal_peptide
Y
Antigen
Type
minigene mRNA
T-cell
Source
PBMCs
APC
Type
None
Assay
None