Immunogenicity 157
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
STAG2
Transcript ID
uc004eue.3
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1268 aa)
MIAAP
1
EIPTD
6
FNLLQ
11
ESETH
16
FSSDT
21
DFEDI
26
EGKNQ
31
KQGKG
36
KTCKK
41
GKKGP
46
AEKGK
51
GGNGG
56
GKPPS
61
GPNRM
66
NGHHQ
71
QNGVE
76
NMMLF
81
EVVKM
86
GKSAM
91
QSVVD
96
DWIES
101
YKHDR
106
DIALL
111
DLINF
116
FIQCS
121
GCKGV
126
VTAEM
131
FRHMQ
136
NSEII
141
RKMTE
146
EFDED
151
SGDYP
156
LTMAG
161
PQWKK
166
FKSSF
171
CEFIG
176
VLVRQ
181
CQYSI
186
IYDEY
191
MMDTV
196
ISLLT
201
GLSDS
206
QVRAF
211
RHTST
216
LAAMK
221
LMTAL
226
VNVAL
231
NLSIN
236
MDNTQ
241
RQYEA
246
ERNKM
251
IGKRA
256
NERLE
261
LLLQK
266
RKELQ
271
ENQDE
276
IENMM
281
NAIFK
286
GVFVH
291
RYRDA
296
IAEIR
301
AICIE
306
EIGIW
311
MKMYS
316
DAFLN
321
DSYLK
326
YVGWT
331
MHDKQ
336
GEVRL
341
KCLTA
346
LQGLY
351
YNKEL
356
NSKLE
361
LFTSR
366
FKDRI
371
VSMTL
376
DKEYD
381
VAVQA
386
IKLLT
391
LVLQS
396
SEEVL
401
TAEDC
406
ENVYH
411
LVYSA
416
HRPVA
421
VAAGE
426
FLYKK
431
LFSRR
436
DPEED
441
GMMKR
446
RGRQG
451
PNANL
456
VKTLV
461
FFFLE
466
SELHE
471
HAAYL
476
VDSMW
481
DCATE
486
LLKDW
491
ECMNS
496
LLLEE
501
PLSGE
506
EALTD
511
RQESA
516
LIEIM
521
LCTIR
526
QAAEC
531
HPPVG
536
RGTGK
541
RVLTA
546
KEKKT
551
QLDDR
556
TKITE
561
LFAVA
566
LPQLL
571
AKYSV
576
DAEKV
581
TNLLQ
586
LPQYF
591
DLEIY
596
TTGRL
601
EKHLD
606
ALLRQ
611
IRNIV
616
EKHTD
621
TDVLE
626
ACSKT
631
YHALC
636
NEEFT
641
IFNRV
646
DISRS
651
QLIDE
656
LADKF
661
NRLLE
666
DFLQE
671
GEEPD
676
EDDAY
681
QVLST
686
LKRIT
691
AFHNA
696
HDLSK
701
WDLFA
706
CNYKL
711
LKTGI
716
ENGDM
721
PEQIV
726
IHALQ
731
CTHYV
736
ILWQL
741
AKITE
746
SSSTK
751
EDLLR
756
LKKQM
761
RVFCQ
766
ICQHY
771
LTNVN
776
TTVKE
781
QAFTI
786
LCDIL
791
MIFSH
796
QIMSG
801
GRDML
806
EPLVY
811
TPDSS
816
LQSEL
821
LSFIL
826
DHVFI
831
EQDDD
836
NNSAD
841
GQQED
846
EASKI
851
EALHK
856
RRNLL
861
AAFCK
866
LIVYT
871
VVEMN
876
TAADI
881
FKQYM
886
KYYND
891
YGDII
896
KETMS
901
KTRQI
906
DKIQC
911
AKTLI
916
LSLQQ
921
LFNEM
926
IQENG
931
YNFDR
936
SSSTF
941
SGIKE
946
LARRF
951
ALTFG
956
LDQLK
961
TREAI
966
AMLHK
971
DGIEF
976
AFKEP
981
NPQGE
986
SHPPL
991
NLAFL
996
DILSE
1001
FSSKL
1006
LRQDK
1011
RTVYV
1016
YLEKF
1021
MTFQM
1026
SLRRE
1031
DVWLP
1036
LMSYR
1041
NSLLA
1046
GGDDD
1051
TMSVI
1056
SGISS
1061
RGSTV
1066
RSKKS
1071
KPSTG
1076
KRKVV
1081
EGMQL
1086
SLTEE
1091
SSSSD
1096
SMWLS
1101
REQTL
1106
HTPVM
1111
MQTPQ
1116
LTSTI
1121
MREPK
1126
RLRPE
1131
DSFMS
1136
VYPMQ
1141
TEHHQ
1146
TPLDY
1151
NTQVT
1156
WMLAQ
1161
RQQEE
1166
ARQQQ
1171
ERAAM
1176
SYVKL
1181
RTNLQ
1186
HAIRR
1191
GTSLM
1196
EDDEE
1201
PIVED
1206
VMMSS
1211
EGRIE
1216
DLNEG
1221
MDFDT
1226
MDIDL
1231
PPSKN
1236
RRERT
1241
ELKPD
1246
FFDPA
1251
SIMDE
1256
SVLGV
1261
SMF
1266
Mutation Information
DNA mutation:
c.A1742T
Peptide Range:
569 ~ 593
Mut AA position:
581 (13 in Wild Type peptide)
Alignment
Wild Type:
"VALPQLLAKYSVDAEKVTNLLQLPQ
||||||||||||.||||||||||||
Mutant:
VALPQLLAKYSVVAEKVTNLLQLPQ"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) STAG2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VALPQLLAKYSVVAEKVTNLLQLPQ
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT