Immunogenicity 15713
Sample ID
3713
Response
Positive
Tumor Type
Melanoma
Gene Symbol
WDR46
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (754 aa)
METAP
1
KPGKD
6
VPPKK
11
DKLQT
16
KRKKP
21
RRYWE
26
EETVP
31
TTAGA
36
SPGPP
41
RNKKN
46
RELRP
51
QRPKN
56
AYILK
61
KSRIS
66
KKPQV
71
PKKPR
76
EWKNP
81
ESQRG
86
LSGTQ
91
DPFPG
96
PAPVP
101
VEVVQ
106
KFCRI
111
DKSRK
116
LPHSK
121
AKTRS
126
RLEVA
131
EAEEE
136
ETSIK
141
AARSE
146
LLLAE
151
EPGFL
156
EGEDG
161
EDTAK
166
ICQAD
171
IVEAV
176
DIASA
181
AKHFD
186
LNLRQ
191
FGPYR
196
LNYSR
201
TGRHL
206
AFGGR
211
RGHVA
216
ALDWV
221
TKKLM
226
CEINV
231
MEAVR
236
DIRFL
241
HSEAL
246
LAVAQ
251
NRWLH
256
IYDNQ
261
GIELH
266
CIRRC
271
DRVTR
276
LEFLP
281
FHFLL
286
ATASE
291
TGFLT
296
YLDVS
301
VGKIV
306
AALNA
311
RAGRL
316
DVMSQ
321
NPYNA
326
VIHLG
331
HSNGT
336
VSLWS
341
PAMKE
346
PLAKI
351
LCHRG
356
GVRAV
361
AVDST
366
GTYMA
371
TSGLD
376
HQLKI
381
FDLRG
386
TYQPL
391
STRTL
396
PHGAG
401
HLAFS
406
QRGLL
411
VAGMG
416
DVVNI
421
WAGQG
426
KASPP
431
SLEQP
436
YLTHR
441
LSGPV
446
HGLQF
451
CPFED
456
VLGVG
461
HTGGI
466
TSMLV
471
PGAGE
476
PNFDG
481
LESNP
486
YRSRK
491
QRQEW
496
EVKAL
501
LEKVP
506
AELIC
511
LDPRA
516
LAEVD
521
VISLE
526
QGKKE
531
QIERL
536
GYDPQ
541
AKAPF
546
QPKPK
551
QKGRS
556
STASL
561
VKRKR
566
KVMDE
571
EHRVN
576
EHWHG
581
PGLPQ
586
AAPSC
591
LCLCP
596
CQPAT
601
SHSVP
606
VSSPS
611
PVPRT
616
RSGRA
621
FSSSI
626
IRRRR
631
PSPRG
636
PGHLP
641
WTDLC
646
AEPDS
651
RVAWE
656
QSLPK
661
ITCRE
666
MSVPW
671
NKEVG
676
AVWPL
681
PQLGV
686
DSCLL
691
GWVGI
696
KEESD
701
FLDNV
706
SGSSC
711
GPVPL
716
PLAKH
721
EAILG
726
SEGSV
731
SCLYP
736
HPIPC
741
GCCGL
746
SFAF
751
Mutation Information
DNA mutation:
None
Peptide Range:
298 ~ 306
Mut AA position:
None (3 in Wild Type peptide)
Alignment
Wild Type:
"FLTYLDVSV
||.||||||
Mutant:
FLIYLDVSV"
Cancer Immunol Res, 2016
Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor AntigensGene Name (from Reference) WDR46
Checkpoint
Blockade
None
ACT
Y
Vaccination
N
Curative
Effect
durable regression
minimal_peptide
Y
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
B cells
Assay
None