Immunogenicity 15735

summary
Sample ID
CR9306
Response
Positive
Tumor Type
Melanoma
Gene Symbol
FAM3C
Transcript ID
None
HLA INFO
B*44:02
TCR INFO

No TCR info found!

T cell Tumor cell B*44:02
sequence
Full length protein sequence (227 aa)
MRVAG
1
AAKLV
6
VAVAV
11
FLLTF
16
YVISQ
21
VFEIK
26
MDASL
31
GNLFA
36
RSALD
41
TAARS
46
TKPPR
51
YKCGI
56
SKACP
61
EKHFA
66
FKMAS
71
GAANV
76
VGPKI
81
CLEDN
86
VLMSG
91
VKNNV
96
GRGIN
101
VALAN
106
GKTGE
111
VLDTK
116
YFDMW
121
GGDVA
126
PFIEF
131
LKAIQ
136
DGTIV
141
LMGTY
146
DDGAT
151
KLNDE
156
ARRLI
161
ADLGS
166
TSITN
171
LGFRD
176
NWVFC
181
GGKGI
186
KTKSP
191
FEQHI
196
KNNKD
201
TNKYE
206
GWPEV
211
VEMEG
216
CIPQK
221
QD
226
Mutation Information
DNA mutation:
None
Peptide Range:
192 ~ 200
Mut AA position:
None (2 in Wild Type peptide)
Alignment
Wild Type:
"TKSPFEQHI
|.|||||||
Mutant:
TESPFEQHI"
reference

N Engl J Med, 2015

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

Gene Name (from Reference) FAM3C

clinic trial
Checkpoint Blockade

ipilimumab

ACT

N

Vaccination

N

Curative Effect

clinical benefit

experiment
minimal_peptide

Y

Antigen Type

multimer

T-cell Source

PBMCs

APC Type

None

Assay

None