Immunogenicity 15738

summary
Sample ID
4032
Response
Positive
Tumor Type
Colorectal cancer
Gene Symbol
API5 (FPKM: 10.3)
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (509 aa)
MPTVE
1
ELYRN
6
YGILA
11
DATEQ
16
VGQHK
21
DAYQV
26
ILDGV
31
KGGTK
36
EKRLA
41
AQFIP
46
KFFKH
51
FPELA
56
DSAIN
61
AQLDL
66
CEDED
71
VSIRR
76
QAIKE
81
LPQFA
86
TGENL
91
PRVAD
96
ILTQL
101
LQTDD
106
SAEFN
111
LVNNA
116
LLSIF
121
KMDAK
126
GTLGG
131
LFSQI
136
LQGED
141
IVRER
146
AIKFL
151
STKLK
156
TLPDE
161
VLTKE
166
VEELI
171
LTESK
176
KVLED
181
VTGEE
186
FVLFM
191
KILSG
196
LKSLQ
201
TVSGR
206
QQLVE
211
LVAEQ
216
ADLEQ
221
TFNPS
226
DPDCV
231
DRLLQ
236
CTRQA
241
VPLFS
246
KNVHS
251
TRFVT
256
YFCEQ
261
VLPNL
266
GTLTT
271
PVEGL
276
DIQLE
281
VLKLL
286
AEMSS
291
FCGDM
296
EKLET
301
NLRKL
306
FDKLL
311
EYMPL
316
PPEEA
321
ENGEN
326
AGNEE
331
PKLQF
336
SYVEC
341
LLYSF
346
HQLGR
351
KLPDF
356
LTAKL
361
NAEKL
366
KDFKI
371
RLQYF
376
ARGLQ
381
VYIRQ
386
LRLAL
391
QGKTG
396
EALKT
401
EENKI
406
KVVAL
411
KITNN
416
INVLI
421
KDLFH
426
IPPSY
431
KSTVT
436
LSWKP
441
VQKVE
446
IGQKR
451
ASEDT
456
TSGSP
461
PKKSS
466
AGPKR
471
DARQI
476
YNPPS
481
GKYSS
486
NLGNF
491
NYERG
496
VKKDI
501
KTSP
506
Mutation Information
DNA mutation:
None
Peptide Range:
238 ~ 246
Mut AA position:
243 (6 in Wild Type peptide)
Alignment
Wild Type:
"LLQCTRQAV
|||||.|||
Mutant:
LLQCTQQAV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) API5

clinic trial
Checkpoint Blockade

None

ACT

N

Vaccination

N

Curative Effect

no objective response

experiment
minimal_peptide

Y

Antigen Type

peptide

T-cell Source

TILs

APC Type

DCs

Assay

None