Immunogenicity 15771
Sample ID
3716
Response
Positive
Tumor Type
Melanoma
Gene Symbol
TFDP2
Transcript ID
None
HLA INFO
B*15:01
TCR INFO
CDR3ACALSDPQDSGYSTLTF
TRBVBV5-4
TRAVAV9-2
CDR3BCASSLGQGRVEQYF
Full length protein sequence (447 aa)
MTAKN
1
VGLTS
6
TNAEV
11
RGFID
16
QNLSP
21
TKGNI
26
SFVAF
31
PVSNT
36
NSPTK
41
ILPKT
46
LGPIN
51
VNVGP
56
QMIIS
61
TPQRL
66
TSSGS
71
VLIGS
76
PYTPA
81
PAMVT
86
QTHIA
91
EATGW
96
VPGDR
101
KRARK
106
FIDSD
111
FSESK
116
RSKKG
121
DKNGK
126
GLRHF
131
SMKVC
136
EKVQR
141
KGTTS
146
YNEVA
151
DELVS
156
EFTNS
161
NNHLA
166
ADSQA
171
YDQKN
176
IRRRV
181
YDALN
186
VLMAM
191
NIISK
196
EKKEI
201
KWIGL
206
PTNSA
211
QECQN
216
LEIEK
221
QRRIE
226
RIKQK
231
RAQLQ
236
ELLLQ
241
QIAFK
246
NLVQR
251
NRQNE
256
QQNQG
261
PPALN
266
STIQL
271
PFIII
276
NTSRK
281
TVIDC
286
SISSD
291
KFEYL
296
FNFDN
301
TFEIH
306
DDIEV
311
LKRMG
316
MSFGL
321
ESGKC
326
SLEDL
331
KLAKS
336
LVPKA
341
LEGYI
346
TDIST
351
GPSWL
356
NQGLL
361
LNSTQ
366
SVSNL
371
DLTTG
376
ATLPQ
381
SSVNQ
386
GLCLD
391
AEVAL
396
ATGQF
401
LAPNS
406
HQSSS
411
AASHC
416
SESRG
421
ETPCS
426
FNDED
431
EEDDE
436
EDSSS
441
PE
446
Mutation Information
DNA mutation:
None
Peptide Range:
403 ~ 411
Mut AA position:
None (5 in Wild Type peptide)
Alignment
Wild Type:
"GQFLAPNSH
||||.||||
Mutant:
GQFLTPNSH"
Clin Cancer Res, 2017
Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 ExpressionGene Name (from Reference) TFDP2
Checkpoint
Blockade
None
ACT
N
Vaccination
N
Curative
Effect
None
minimal_peptide
Y
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
DCs
Assay
None