Immunogenicity 15797
Sample ID
TIL2369
Response
Positive
Tumor Type
Melanoma
Gene Symbol
PLEKHM2
Transcript ID
None
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1032 aa)
MNQSC
1
IQQVG
6
ACMHP
11
SQDGV
16
GRKCA
21
ILTPQ
26
TPLLQ
31
SYFAA
36
CEDEI
41
PAIRN
46
HDKVL
51
QRLCE
56
HLDHA
61
LLYGL
66
QDLSS
71
GYWVL
76
VVHFT
81
RREAI
86
KQIEV
91
LQHVA
96
TNLGR
101
SRAWL
106
YLALN
111
ENSLE
116
SYLRL
121
FQENL
126
GLLHK
131
YYVKN
136
ALVCS
141
HDHLT
146
LFLTL
151
VSGLE
156
FIRFE
161
LDLDA
166
PYLDL
171
APYMP
176
DYYKP
181
QYLLD
186
FEDRL
191
PSSVH
196
GSDSL
201
SLNSF
206
NSVTS
211
TNLEW
216
DDSAI
221
APSSE
226
DYDFG
231
DVFPA
236
VPSVP
241
STDWE
246
DGDLT
251
DTVSG
256
PRSTA
261
SDLTS
266
SKAST
271
RSPTQ
276
RQNPF
281
NEEPA
286
ETVSS
291
SDTTP
296
VHTTS
301
QEKEE
306
AQALD
311
PPDAC
316
TELEV
321
IRVTK
326
KKKIG
331
KKKKS
336
RSDEE
341
ASPLH
346
PACSQ
351
KKCAK
356
QGDGD
361
SRNGS
366
PSLGR
371
DSPDT
376
MLASP
381
QEEGE
386
GPSST
391
TESSE
396
RSEPG
401
LLIPE
406
MKDTS
411
MERLG
416
QPLSK
421
VIDQL
426
NGQLD
431
PSTWC
436
SRAEP
441
PDQSF
446
RTGSP
451
GDAPE
456
RPPLC
461
DFSEG
466
LSAPM
471
DFYRF
476
TVESP
481
STVTS
486
GGGHH
491
DPAGL
496
GQPLH
501
VPSSP
506
EAAGQ
511
EEEGG
516
GGEGQ
521
TPRPL
526
EDTTR
531
EAQEL
536
EAQLS
541
LVREG
546
PVSEP
551
EPGTQ
556
EVLCQ
561
LKRDQ
566
PSPCL
571
SSAED
576
SGVDE
581
GQGSP
586
SEMVH
591
SSEFR
596
VDNNH
601
LLLLM
606
IHVFR
611
ENEEQ
616
LFKMI
621
RMSTG
626
HMEGN
631
LQLLY
636
VLLTD
641
CYVYL
646
LRKGA
651
TEKPY
656
LVEEA
661
VSYNE
666
LDYVS
671
VGLDQ
676
QTVKL
681
VCTNR
686
RKQFL
691
LDTAD
696
VALAE
701
FFLAS
706
LKSAM
711
IKGCR
716
EPPYP
721
SILTD
726
ATMEK
731
LALAK
736
FVAQE
741
SKCEA
746
SAVTV
751
RFYGL
756
VHWED
761
PTDES
766
LGPTP
771
CHCSP
776
PEGTI
781
TKEGM
786
LHYKA
791
GTSYL
796
GKEHW
801
KTCFV
806
VLSNG
811
ILYQY
816
PDRTD
821
VIPLL
826
SVNMG
831
GEQCG
836
GCRRA
841
NTTDR
846
PHAFQ
851
VILSD
856
RPCLE
861
LSAES
866
EAEMA
871
EWMQH
876
LCQAV
881
SKGVI
886
PQGVA
891
PSPCI
896
PCCLV
901
LTDDR
906
LFTCH
911
EDCQT
916
SFFRS
921
LGTAK
926
LGDIS
931
AVSTE
936
PGKEY
941
CVLEF
946
SQDSQ
951
QLLPP
956
WVIYL
961
SCTSE
966
LDRLL
971
SALNS
976
GWKTI
981
YQVDL
986
PHTAI
991
QEASN
996
KKKFE
1001
DALSL
1006
IHSAW
1011
QRSDS
1016
LCRGR
1021
ASRDP
1026
WC
1031
Mutation Information
DNA mutation:
None
Peptide Range:
906 ~ 915
Mut AA position:
None (10 in Wild Type peptide)
Alignment
Wild Type:
"LTDDRLFTCH
|||||||||.
Mutant:
LTDDRLFTCY"
Nat Med, 2013
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cellsGene Name (from Reference) PLEKHM2
Checkpoint
Blockade
None
ACT
Y
Vaccination
N
Curative
Effect
complete regression
minimal_peptide
Y
Antigen
Type
multimer
T-cell
Source
TILs
APC
Type
T2
Assay
None