Immunogenicity 15811
Sample ID
P11-SPOP-N147I
Response
Positive
Tumor Type
Melanoma
Gene Symbol
SPOP
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (374 aa)
MSRVP
1
SPPPP
6
AEMSS
11
GPVAE
16
SWCYT
21
QIKVV
26
KFSYM
31
WTINN
36
FSFCR
41
EEMGE
46
VIKSS
51
TFSSG
56
ANDKL
61
KWCLR
66
VNPKG
71
LDEES
76
KDYLS
81
LYLLL
86
VSCPK
91
SEVRA
96
KFKFS
101
ILNAK
106
GEETK
111
AMESQ
116
RAYRF
121
VQGKD
126
WGFKK
131
FIRRD
136
FLLDE
141
ANGLL
146
PDDKL
151
TLFCE
156
VSVVQ
161
DSVNI
166
SGQNT
171
MNMVK
176
VPECR
181
LADEL
186
GGLWE
191
NSRFT
196
DCCLC
201
VAGQE
206
FQAHK
211
AILAA
216
RSPVF
221
SAMFE
226
HEMEE
231
SKKNR
236
VEIND
241
VEPEV
246
FKEMM
251
CFIYT
256
GKAPN
261
LDKMA
266
DDLLA
271
AADKY
276
ALERL
281
KVMCE
286
DALCS
291
NLSVE
296
NAAEI
301
LILAD
306
LHSAD
311
QLKTQ
316
AVDFI
321
NYHAS
326
DVLET
331
SGWKS
336
MVVSH
341
PHLVA
346
EAYRS
351
LASAQ
356
CPFLG
361
PPRKR
366
LKQS
371
Mutation Information
DNA mutation:
None
Peptide Range:
141 ~ 149
Mut AA position:
147 (7 in Wild Type peptide)
Alignment
Wild Type:
"FLLDEANGL
||||||.||
Mutant:
FLLDEAIGL"
Nature, 2017
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancerGene Name (from Reference) SPOP
Checkpoint
Blockade
None
ACT
N
Vaccination
Y
Curative
Effect
disease free
minimal_peptide
Y
Antigen
Type
multimer
T-cell
Source
PBL
APC
Type
multimer
Assay
None