Immunogenicity 15824

summary
Sample ID
P04-DOPEY2-R365C
Response
Positive
Tumor Type
Melanoma
Gene Symbol
DOPEY2
Transcript ID
None
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (2298 aa)
MDPEE
1
QELLN
6
DYRYR
11
SYSSV
16
IEKAL
21
RNFES
26
SSEWA
31
DLISS
36
LGKLN
41
KALQS
46
NLRYS
51
LLPRR
56
LLISK
61
RLAQC
66
LHPAL
71
PSGVH
76
LKALE
81
TYEII
86
FKIVG
91
TKWLA
96
KDLFL
101
YSCGL
106
FPLLA
111
HAAVS
116
VRPVL
121
LTLYE
126
KYFLP
131
LQKLL
136
LPSLQ
141
AFIVG
146
LLPGL
151
EEGSE
156
ISDRT
161
DALLL
166
RLSLV
171
VGKEV
176
FYTAL
181
WGSVL
186
ASPSI
191
RLPAS
196
VFVVG
201
HINRD
206
APGRE
211
QKYML
216
GTNHQ
221
LTVKS
226
LRASL
231
LDSNV
236
LVQRN
241
NLEIV
246
LFFFP
251
FYTCL
256
DSNER
261
AIPLL
266
RSDIV
271
RILSA
276
ATQTL
281
LRRDM
286
SLNRR
291
LYAWL
296
LGSDI
301
KGNTV
306
VPESE
311
ISNSY
316
EDQSS
321
YFFEK
326
YSKDL
331
LVEGL
336
AEILH
341
QKFID
346
ADVEE
351
RHHAY
356
LKPFR
361
VLISL
366
LDKPE
371
IGPQV
376
VGNLF
381
LEVIR
386
AFYSY
391
CRDAL
396
GSDLK
401
LSYTQ
406
SGNSL
411
ISAIK
416
ENRNA
421
SEIVK
426
TVNLL
431
ITSLS
436
TDFLW
441
DYMTR
446
CFEEC
451
FRPVK
456
QRYSV
461
RNSVS
466
PPPTV
471
SELCA
476
LLVFL
481
LDVIP
486
LELYS
491
EVQTQ
496
YLPQV
501
LGCLV
506
QPLAE
511
DMEAL
516
SLPEL
521
THALK
526
TCFKV
531
LSKVQ
536
MPPSY
541
LDTES
546
TSGTS
551
SPVKG
556
ENGKI
561
ILETK
566
AVIPG
571
DEDAS
576
FPPLK
581
SEDSG
586
IGLSA
591
SSPEL
596
SEHLR
601
VPRVS
606
LERDD
611
VWKKG
616
GSMQR
621
TFLCI
626
QELIA
631
NFASK
636
NIFGV
641
QLTAS
646
GEESK
651
SEEPA
656
GKRDR
661
DGTQS
666
LAAND
671
SSRKN
676
SWEPK
681
PITVP
686
QFKQM
691
LSDLF
696
TARGS
701
PFKTK
706
SSESP
711
SSSPS
716
SPARK
721
NGGEW
726
DVEKV
731
VIDLG
736
GSREE
741
RREAF
746
AAACH
751
LLLDC
756
ATFPV
761
YLSEE
766
ETEQL
771
CATLF
776
QLPGA
781
GDSSF
786
PSWLK
791
SLMTI
796
CCCVT
801
DCYLQ
806
NVAIS
811
TLLEV
816
INHSQ
821
SLALV
826
IEDKM
831
KRYKS
836
SGHNP
841
FFGKL
846
QMVTV
851
PPIAP
856
GILKV
861
IAEKT
866
DFYQR
871
VARVL
876
WNQLN
881
KETRE
886
HHVTC
891
VELFY
896
RLHCL
901
APTAN
906
ICEDI
911
ICHAL
916
LDPDK
921
GTRLE
926
ALFRF
931
SVIWH
936
LTREI
941
QGSRV
946
TSHNR
951
SFDRS
956
LFVVL
961
DSLAC
966
TDGAI
971
GAAAQ
976
GWLVR
981
ALSLG
986
DVARI
991
LEPVL
996
LLLLQ
1001
PKTQR
1006
TSIHC
1011
LKQEN
1016
SADDL
1021
HRWFN
1026
RKKTS
1031
FREAC
1036
AVPEP
1041
QESGS
1046
EEHLP
1051
LSQFT
1056
TVDRE
1061
AIWAE
1066
VEKEP
1071
EKYPL
1076
RGELS
1081
EEELP
1086
YYVEL
1091
PDRTA
1096
HGAPD
1101
SSEHT
1106
ESADT
1111
SSCHT
1116
DSENT
1121
SSFSS
1126
PSHDL
1131
QELSN
1136
EENCC
1141
APIPM
1146
GGRAY
1151
PKRSA
1156
LLAAF
1161
QSESF
1166
KAGAK
1171
LSLVR
1176
VDSDK
1181
TQASE
1186
SFSSD
1191
EEADL
1196
ELQAL
1201
TTSRL
1206
LKQQR
1211
ERQEA
1216
VEALF
1221
KHILL
1226
YLQPY
1231
DSRRV
1236
LYAFS
1241
VLEAV
1246
LKTNP
1251
KEFIE
1256
AVSRT
1261
SMDTS
1266
STAHL
1271
NLISN
1276
LLARH
1281
QEALI
1286
GQSFY
1291
GKLQT
1296
QVPNV
1301
CPHSL
1306
LLELL
1311
TYLCL
1316
SFLRS
1321
YYPCY
1326
LKVSH
1331
RDILG
1336
NRDVQ
1341
VKSVE
1346
VLIRI
1351
MMQLV
1356
SVAKS
1361
SEGKN
1366
VEFIH
1371
SLLQR
1376
CKVQE
1381
FVLLS
1386
LSASM
1391
YTSQK
1396
RYGLA
1401
TAHHG
1406
RALPE
1411
DSLFE
1416
ESLIN
1421
LGQDQ
1426
IWSEH
1431
PLQIE
1436
LLKLL
1441
QVLIV
1446
LEHHL
1451
GRAHE
1456
EAENQ
1461
PDLSR
1466
EWQRA
1471
LNFQQ
1476
AISAL
1481
QYVQP
1486
HPLTS
1491
QGLLV
1496
SAVVR
1501
GLQPA
1506
YGYGM
1511
HPAWV
1516
SLVTH
1521
SLPYF
1526
GKSLG
1531
WTVTP
1536
FVVQI
1541
CKNLD
1546
DLVKQ
1551
YESES
1556
VKLSV
1561
STTSK
1566
RENIS
1571
PDYPL
1576
TLLEG
1581
LTTIS
1586
HFCLL
1591
EQANQ
1596
NKKTM
1601
AAGDP
1606
ANLRN
1611
ARNAI
1616
LEELP
1621
RTVNT
1626
MALLW
1631
NVLRK
1636
EETQK
1641
RPVDL
1646
LGATK
1651
GSSSV
1656
YFKTT
1661
KTIRQ
1666
KILDF
1671
LNPLT
1676
AHLGV
1681
QLTAA
1686
VAAVW
1691
SRKKA
1696
QRHSK
1701
MKIIP
1706
TASAS
1711
QLTLV
1716
DLVCA
1721
LSTLQ
1726
TDTLL
1731
HLVKE
1736
VVKRP
1741
PQVKG
1746
GDEKS
1751
PLVDI
1756
PVLQF
1761
CYAFL
1766
QRLPV
1771
PALQE
1776
NFSSL
1781
LGVLK
1786
ESVQL
1791
NLAPP
1796
GYFLL
1801
LSMLN
1806
DFVTR
1811
TPNLE
1816
NKKDQ
1821
KDLQE
1826
ITQKI
1831
LEAVG
1836
NIAGS
1841
SLEQT
1846
SWLSR
1851
NLEVK
1856
AQPQA
1861
SLEES
1866
DAEED
1871
LYDAA
1876
AASAM
1881
VSSSA
1886
PSVYS
1891
VQALS
1896
LLAEV
1901
LASLL
1906
DMVYR
1911
SDEKE
1916
KAVPL
1921
ISRLL
1926
YYVFP
1931
YLRNH
1936
SAYNA
1941
PSFRA
1946
GAQLL
1951
SSLSG
1956
YAYTK
1961
RAWRK
1966
EVLEL
1971
FLDPA
1976
FFQMD
1981
TSCVH
1986
WKSII
1991
DHLLT
1996
HEKTM
2001
FKDLM
2006
NMQSS
2011
SLKLF
2016
SSFEQ
2021
KAMLL
2026
KRQAF
2031
AVFSG
2036
ELDQY
2041
HLYLP
2046
LIQER
2051
LTDNL
2056
RVGQT
2061
SIVAA
2066
QMFLF
2071
FRVLL
2076
LRISP
2081
QHLTS
2086
LWPIM
2091
VSELI
2096
QTFTQ
2101
LEEDL
2106
KDEDE
2111
SLRST
2116
NKVNR
2121
TKVSV
2126
PDANG
2131
PSVGE
2136
IPQSE
2141
LILYL
2146
SACKF
2151
LDTAL
2156
SFPPD
2161
KMPLF
2166
QIYRW
2171
AFIPE
2176
VDTEG
2181
PAFLS
2186
DVEEN
2191
HQECK
2196
PHTVR
2201
ILELL
2206
KLKFG
2211
EISSS
2216
DEITM
2221
KSEFP
2226
LLRQH
2231
SVSSI
2236
RQLMP
2241
FFMTL
2246
NGAFK
2251
TQRQL
2256
PADSP
2261
GTPFL
2266
DFPVT
2271
DSPRI
2276
LKQLE
2281
ECIEY
2286
DFLEH
2291
PEC
2296
Mutation Information
DNA mutation:
None
Peptide Range:
362 ~ 370
Mut AA position:
365 (4 in Wild Type peptide)
Alignment
Wild Type:
"KPFRVLISL
|||.|||||
Mutant:
KPFCVLISL"
reference
clinic trial
Checkpoint Blockade

None

ACT

N

Vaccination

Y

Curative Effect

Metastasis

experiment
minimal_peptide

Y

Antigen Type

multimer

T-cell Source

PBL

APC Type

multimer

Assay

None