Immunogenicity 15825
Sample ID
P05-TTBK2-S1181L
Response
Positive
Tumor Type
Melanoma
Gene Symbol
TTBK2
Transcript ID
None
HLA INFO
B*07:02
TCR INFO
No TCR info found!
Full length protein sequence (1244 aa)
MSGGG
1
EQLDI
6
LSVGI
11
LVKER
16
WKVLR
21
KIGGG
26
GFGEI
31
YDALD
36
MLTRE
41
NVALK
46
VESAQ
51
QPKQV
56
LKMEV
61
AVLKK
66
LQGKD
71
HVCRF
76
IGCGR
81
NDRFN
86
YVVMQ
91
LQGRN
96
LADLR
101
RSQSR
106
GTFTI
111
STTLR
116
LGRQI
121
LESIE
126
SIHSV
131
GFLHR
136
DIKPS
141
NFAMG
146
RFPST
151
CRKCY
156
MLDFG
161
LARQF
166
TNSCG
171
DVRPP
176
RAVAG
181
FRGTV
186
RYASI
191
NAHRN
196
REMGR
201
HDDLW
206
SLFYM
211
LVEFV
216
VGQLP
221
WRKIK
226
DKEQV
231
GSIKE
236
RYDHR
241
LMLKH
246
LPPEF
251
SIFLD
256
HISSL
261
DYFTK
266
PDYQL
271
LTSVF
276
DNSIK
281
TFGVI
286
ESDPF
291
DWEKT
296
GNDGS
301
LTTTT
306
TSTTP
311
QLHTR
316
LTPAA
321
IGIAN
326
ATPIP
331
GDLLR
336
ENTDE
341
VFPDE
346
QLSDG
351
ENGIP
356
VGVSP
361
DKLPG
366
SLGHP
371
RPQEK
376
DVWEE
381
MDANK
386
NKIKL
391
GICKA
396
ATEEE
401
NSHGQ
406
ANGLL
411
NAPSL
416
GSPIR
421
VRSEI
426
TQPDR
431
DIPLV
436
RKLRS
441
IHSFE
446
LEKRL
451
TLEPK
456
PDTDK
461
FLETC
466
LEKMQ
471
KDTSA
476
GKESI
481
LPALL
486
HKPCV
491
PAVSR
496
TDHIW
501
HYDEE
506
YLPDA
511
SKPAS
516
ANTPE
521
QADGG
526
GSNGF
531
IAVNL
536
SSCKQ
541
EIDSK
546
EWVIV
551
DKEQD
556
LQDFR
561
TNEAV
566
GHKTT
571
GSPSD
576
EEPEV
581
LQVLE
586
ASPQD
591
EKLQL
596
GPWAE
601
NDHLK
606
KETSG
611
VVLAL
616
SAEGP
621
PTAAS
626
EQYTD
631
RLELQ
636
PGAAS
641
QFIAA
646
TPTSL
651
MEAQA
656
EGPLT
661
AITIP
666
RPSVA
671
STQST
676
SGSFH
681
CGQQP
686
EKKDL
691
QPMEP
696
TVELY
701
SPREN
706
FSGLV
711
VTEGE
716
PPSGG
721
SRTDL
726
GLQID
731
HIGHD
736
MLPNI
741
RESNK
746
SQDLG
751
PKELP
756
DHNRL
761
VVREF
766
ENLPG
771
ETEEK
776
SILLE
781
SDNED
786
EKLSR
791
GQHCI
796
EISSL
801
PGDLV
806
IVEKD
811
HSATT
816
EPLDV
821
TKTQT
826
FSVVP
831
NQDKN
836
NEIMK
841
LLTVG
846
TSEIS
851
SRDID
856
PHVEG
861
QIGQV
866
AEMQK
871
NKISK
876
DDDIM
881
SEDLP
886
GHQGD
891
LSTFL
896
HQEGK
901
REKIT
906
PRNGE
911
LFHCV
916
SENEH
921
GAPTR
926
KDMVR
931
SSFVT
936
RHSRI
941
PVLAQ
946
EIDST
951
LESSS
956
PVSAK
961
EKLLQ
966
KKAYQ
971
PDLVK
976
LLVEK
981
RQFKS
986
FLGDL
991
SSASD
996
KLLEE
1001
KLATV
1006
PAPFC
1011
EEEVL
1016
TPFSR
1021
LTVDS
1026
HLSRS
1031
AEDSF
1036
LSPII
1041
SQSRK
1046
SKIPR
1051
PVSWV
1056
NTDQV
1061
NSSTS
1066
SQFFP
1071
RPPPG
1076
KPPTR
1081
PGVEA
1086
RLRRY
1091
KVLGS
1096
SNSDS
1101
DLFSR
1106
LAQIL
1111
QNGSQ
1116
KPRST
1121
TQCKS
1126
PGSPH
1131
NPKTP
1136
PKSPV
1141
VPRRS
1146
PSASP
1151
RSSSL
1156
PRTSS
1161
SSPSR
1166
AGRPH
1171
HDQRS
1176
SSPHL
1181
GRSKS
1186
PPSHS
1191
GSSSS
1196
RRSCQ
1201
QEHCK
1206
PSKNG
1211
LKGSG
1216
SLHHH
1221
SASTK
1226
TPQGK
1231
SKPAS
1236
KLSR
1241
Mutation Information
DNA mutation:
None
Peptide Range:
1173 ~ 1181
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"RPHHDQRSS
||||||||.
Mutant:
RPHHDQRSL"
Nature, 2017
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancerGene Name (from Reference) TTBK2
Checkpoint
Blockade
None
ACT
N
Vaccination
Y
Curative
Effect
disease free
minimal_peptide
Y
Antigen
Type
multimer
T-cell
Source
PBL
APC
Type
multimer
Assay
None